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- Olin, Axel, et al.
(author)
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Stereotypic Immune System Development in Newborn Children
- 2018
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In: Cell. - : CELL PRESS. - 0092-8674 .- 1097-4172. ; 174:5, s. 1277-
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Journal article (peer-reviewed)abstract
- Epidemiological data suggest that early life exposures are key determinants of immune-mediated disease later in life. Young children are also particularly susceptible to infections, warranting more analyses of immune system development early in life. Such analyses mostly have been performed in mouse models or human cord blood samples, but these cannot account for the complex environmental exposures influencing human newborns after birth. Here, we performed longitudinal analyses in 100 newborn children, sampled up to 4 times during their first 3 months of life. From 100 mu L of blood, we analyze the development of 58 immune cell populations by mass cytometry and 267 plasma proteins by immunoassays, uncovering drastic changes not predictable from cord blood measurements but following a stereotypic pattern. Preterm and term children differ at birth but converge onto a shared trajectory, seemingly driven by microbial interactions and hampered by early gut bacterial dysbiosis.
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| 3. |
- Appelgren, Staffan, 1967, et al.
(author)
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Growing in Motion: The Circulation of Used Things on Second-hand Markets
- 2015
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In: Culture Unbound. Journal of Current Cultural Research. - 2000-1525. ; 7:1, s. 143-168
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Journal article (peer-reviewed)abstract
- From having been associated with poverty and low status, the commerce with second-hand goods in retro shops, flea markets, vintage boutiques and trade via Internet is expanding in Sweden as in many countries in the Global North. This article argues that a significant aspect of the recent interest in second-hand and reuse concerns the meaningfulness of circulation in social life. Using classic an- thropological theory on how the circulation of material culture generates sociality, it focuses on how second-hand things are transformed by their circulation. Rather than merely having cultural biographies, second-hand things are reconfigured through their shifts between different social contexts in a process that here is un- derstood as a form of growing. Similar to that of an organism, this growth is con- tinuous, irreversible and dependent on forces both internal and external to it. What emerges is a category of things that combine elements of both commodities and gifts, as these have been theorized within anthropology. While first cycle com- modities are purified of their sociality, the hybrid second-hand thing derives its ontological status as well as social and commercial value precisely from retaining ‘gift qualities’, produced by its circulation.
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| 4. |
- Appelgren, Staffan, 1967, et al.
(author)
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Harnessing the Unruly: Anthropological Contributions in Applied Reuse Projects
- 2020
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In: kritisk etnografi: Swedish Journal of Anthropology. - 2003-1173. ; 3:2, s. 87-103
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Journal article (peer-reviewed)abstract
- This article discusses the experiences of two anthropologists working on two applied collaborative projects, both with a focus on sustainable consumption, and both spin-offs from a more conventional academic research project on second-hand and reuse. Although different – one focusing on the reuse of office furniture in the public sector, the other on co-creating an exhibition at a state-run museum – both entailed interventions aiming to stimulate a transition to less damaging ways of living and consuming. Collaborating with a municipality, a state-run museum and a reuse design company, as well as various professional stakeholders in the sector, the anthropologists outline how being ‘unruly’ – probing deeper into seemingly self-evident questions, recontextualising issues, and making associations between domains – allowed them to provide new perspectives and formulate alternative understandings of how to meet the challenges. The main contributions of anthropology in applied settings are often said to be the methodological tools and techniques of the discipline, but in this case, insights from posthumanism significantly shaped the outcomes of the two projects. The authors argue that abstract theoretical insights can play an important role in providing solutions or understandings in concrete, applied situations.
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| 8. |
- Axelin, Anna, et al.
(author)
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Symptoms of depression in parents after discharge from NICU associated with family-centred care
- 2022
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In: Journal of Advanced Nursing. - : John Wiley & Sons. - 0309-2402 .- 1365-2648. ; 78:6, s. 1676-1687
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Journal article (peer-reviewed)abstract
- AIMS: The aim of this study was to examine the potential association of family-centred care as perceived by parents during a NICU stay with parents' depressive symptoms at discharge and at 4 months corrected for infant age.DESIGN: A longitudinal, multicentre cohort study was conducted from 2018 to 2020 in 23 NICUs across 15 countries.METHODS: Parents (n = 635 mothers, n = 466, fathers) of infants (n = 739) born before 35 weeks of gestation and admitted to the participating NICUs were enrolled to the study during the first weeks of their infants' hospitalizations. They responded to Digi-FCC daily text messages inquiring about their perception of family-centred care provided by NICU staff. In addition, they completed a questionnaire assessing their overall perception of family-centred care at discharge. Parents' depressive symptoms were measured by the Edinburgh Postnatal Depression Scale at discharge and again after discharge when their infants were at 4 months corrected for age.RESULTS: The mothers' and the fathers' perceptions of family-centred care were associated with their depressive symptoms at discharge and at 4 months corrected age, controlling for gestational age, multiple birth, parent education and relationship status. Parents' participation in infant care, care-related decisions and emotional support provided to parents by staff explained the variation in the parents' perceptions of family-centred care. The factors facilitating the implementation of family-centred care included unlimited access to the unit for the parents and for their significant others, as well as amenities for parents.CONCLUSIONS: Our study shows that family-centred NICU care associates with parents' depressive symptoms after a NICU stay.IMPACT: Depression is common in parents of preterm infants. The provision of family-centred care may protect the mental well-being of parents of preterm infants.
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