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1.	De Laere, B, et al. (author) Androgen Receptor Burden and Poor Response to Abiraterone or Enzalutamide in TP53 Wild-Type Metastatic Castration-Resistant Prostate Cancer 2019 In: JAMA oncology. - : American Medical Association (AMA). - 2374-2445 .- 2374-2437. ; 5:7, s. 1060-1062 Journal article (peer-reviewed)
2.	De Laere, B, et al. (author) TP53 Outperforms Other Androgen Receptor Biomarkers to Predict Abiraterone or Enzalutamide Outcome in Metastatic Castration-Resistant Prostate Cancer 2019 In: Clinical cancer research : an official journal of the American Association for Cancer Research. - 1557-3265. ; 25:6, s. 1766-1773 Journal article (peer-reviewed)
3.	Mayrhofer, M, et al. (author) Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis 2018 In: Genome medicine. - : Springer Science and Business Media LLC. - 1756-994X. ; 10:1, s. 85- Journal article (peer-reviewed)
4.	Exner, T. E., et al. (author) OpenRiskNet, an open e-infrastructure to support data sharing, knowledge integration and in silico analysis and modelling in risk assessment 2018 In: Toxicology Letters. - : Elsevier BV. - 0378-4274 .- 1879-3169. ; 295, s. S104-S104 Journal article (other academic/artistic)
5.	Lousen, B., et al. (author) Compressing a Non-Planar Aromatic Heterocyclic [7]Helicene to a Planar Hetero[8]Circulene 2020 In: Chemistry - A European Journal. - : Wiley. - 0947-6539 .- 1521-3765. ; 26:22, s. 4935-4940 Journal article (peer-reviewed)abstract This work describes a synthetic approach where a non-planar aromatic heterocyclic [7]helicene is compressed to yield a hetero[8]circulene containing an inner antiaromatic cyclooctatetraene (COT) core. This [8]circulene consists of four benzene rings and four heterocyclic rings, and it is the first heterocyclic [8]circulene containing three different heteroatoms. The synthetic pathway proceeds via a the flattened dehydro-hetero[7]helicene, which is partially a helicene and partially a circulene: it is non-planar and helically chiral as helicenes, and contains a COT motif like [8]circulenes. The antiaromaticity of the COT core is confirmed by nucleus independent chemical shift (NICS) calculations. The planarization from a helically π-conjugated [7]helicene to a fully planar heterocyclic [8]circulene significantly alters the spectroscopic properties of the molecules. Post-functionalization of the [7]helicenes and the [8]circulenes by oxygenation of the thiophene rings to the corresponding thiophene-sulfones allows an almost complete fluorescence emission coverage of the visible region of the optical spectrum (400–700 nm).

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Type of publication: journal article (5)

Type of content: peer-reviewed (4); other academic/artistic (1)

Author/Editor: Schrijvers, D (3); Ampe, J. (3); Rantalainen, M (3); Lindberg, J (3); Gronberg, H (3); Yachnin, J (3); show more...; Ullen, A (3); Brouwers, B (3); De Laere, B (3); van Dam, PJ (3); Ost, P (3); Whitington, T. (3); Rajan, P (3); Mayrhofer, M (3); Van Oyen, P (3); Ghysel, C (3); Demey, W (3); Lybaert, W (3); De Maeseneer, D (3); Strijbos, M (3); Bols, A (3); Fransis, K (3); Rutten, A (3); Dirix, L. (2); Goossens, D (2); Del-Favero, J (2); Van den Eynden, G (2); BROUWER, A (2); Van Laere, S (2); Everaert, E (2); Beije, N (2); van Dam, V (2); Heyrman, L (2); Sleijfer, S (2); Egevad, L (1); Ågren, Hans (1); Sarimveis, H (1); Doganis, P (1); Willighagen, E (1); Lynch, I (1); Spjuth, Ola, Docent, ... (1); Aly, M (1); Herman, S (1); Nordstrom, T (1); Baryshnikov, Gleb V. (1); Kramer, S (1); Van den Eynden, GG (1); Hammerich, O. (1); Hoela, L (1); de Kruijff, I (1); show less...

University: Karolinska Institutet (3); Royal Institute of Technology (1); Uppsala University (1)

Language: English (5)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

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