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Träfflista för sökning "WFRF:(Broberg E) "

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1.	Arouca, AB, et al. (author) Diet as a moderator in the association of sedentary behaviors with inflammatory biomarkers among adolescents in the HELENA study 2019 In: European journal of nutrition. - : Springer Science and Business Media LLC. - 1436-6215 .- 1436-6207. ; 58:5, s. 2051-2065 Journal article (peer-reviewed)
2.	Gimenez-Legarre, N, et al. (author) Dietary Patterns and Their Relationship With the Perceptions of Healthy Eating in European Adolescents: The HELENA Study 2019 In: Journal of the American College of Nutrition. - : Informa UK Limited. - 1541-1087 .- 0731-5724. ; 38:8, s. 703-713 Journal article (peer-reviewed)
3.	Collese, TS, et al. (author) How do energy balance-related behaviors cluster in adolescents? 2019 In: International journal of public health. - : Springer Science and Business Media LLC. - 1661-8564 .- 1661-8556. ; 64:2, s. 195-208 Journal article (peer-reviewed)
4.	Santos, TSS, et al. (author) Measuring nutritional knowledge using Item Response Theory and its validity in European adolescents 2019 In: Public health nutrition. - 1475-2727. ; 22:3, s. 419-430 Journal article (peer-reviewed)
5.	Milne, RL, et al. (author) Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:12, s. 1767-1778 Journal article (peer-reviewed)
6.	Michailidou, K, et al. (author) Association analysis identifies 65 new breast cancer risk loci 2017 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 551:7678, s. 92- Journal article (peer-reviewed)
7.	Phelan, CM, et al. (author) Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:5, s. 680-691 Journal article (peer-reviewed)
8.	Escala-Garcia, M, et al. (author) Genome-wide association study of germline variants and breast cancer-specific mortality 2019 In: British journal of cancer. - : Springer Science and Business Media LLC. - 1532-1827 .- 0007-0920. ; 120:6, s. 647-657 Journal article (peer-reviewed)
9.	Shu, Xiang, et al. (author) Associations of obesity and circulating insulin and glucose with breast cancer risk : a Mendelian randomization analysis 2019 In: International Journal of Epidemiology. - : OXFORD UNIV PRESS. - 0300-5771 .- 1464-3685. ; 48:3, s. 795-806 Journal article (peer-reviewed)abstract Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this common malignancy. Findings from previous studies, however, have been inconsistent, and the nature of the associations is unclear. Methods: We conducted Mendelian randomization analyses to evaluate the association of breast cancer risk, using genetic instruments, with fasting insulin, fasting glucose, 2-h glucose, body mass index (BMI) and BMI-adjusted waist-hip-ratio (WHRadj BMI). We first confirmed the association of these instruments with type 2 diabetes risk in a large diabetes genome-wide association study consortium. We then investigated their associations with breast cancer risk using individual-level data obtained from 98 842 cases and 83 464 controls of European descent in the Breast Cancer Association Consortium. Results: All sets of instruments were associated with risk of type 2 diabetes. Associations with breast cancer risk were found for genetically predicted fasting insulin [odds ratio (OR) = 1.71 per standard deviation (SD) increase, 95% confidence interval (CI) = 1.26-2.31, p = 5.09 x 10(-4)], 2-h glucose (OR = 1.80 per SD increase, 95% CI = 1.3 0-2.49, p = 4.02 x 10(-4)), BMI (OR = 0.70 per 5-unit increase, 95% CI = 0.65-0.76, p = 5.05 x 10(-19)) and WHRadj BMI (OR = 0.85, 95% CI = 0.79-0.91, p = 9.22 x 10(-6)). Stratified analyses showed that genetically predicted fasting insulin was more closely related to risk of estrogen-receptor [ER]-positive cancer, whereas the associations with instruments of 2h glucose, BMI and WHRadj BMI were consistent regardless of age, menopausal status, estrogen receptor status and family history of breast cancer. Conclusions: We confirmed the previously reported inverse association of genetically predicted BMI with breast cancer risk, and showed a positive association of genetically predicted fasting insulin and 2-h glucose and an inverse association of WHRadj BMI with breast cancer risk. Our study suggests that genetically determined obesity and glucose/insulin-related traits have an important role in the aetiology of breast cancer.
10.	Wu, Lang, et al. (author) A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer. 2018 In: Nature Genetics. - : Springer Science and Business Media LLC. - 1061-4036 .- 1546-1718. ; 50:7, s. 968-978 Journal article (peer-reviewed)abstract , including 14 genes at loci not yet reported for breast cancer. We silenced 13 genes and showed an effect for 11 on cell proliferation and/or colony-forming efficiency. Our study provides new insights into breast cancer genetics and biology.

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Result 1-10 of 117

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Type of publication: journal article (83); conference paper (27); research review (3); book chapter (3); editorial collection (1)

Type of content: peer-reviewed (86); other academic/artistic (29); pop. science, debate, etc. (2)

Author/Editor: Broberg, Anders G, 1 ... (30); Hwang, Philip, 1950 (29); Lamb, M. E. (29); Broberg, Karin (25); Wardell, E (13); Sylven, C (11); show more...; Grinnemo, KH (11); Pineda, Daniela (9); Mansson-Broberg, A (9); Broberg, Per (9); Olsson, Håkan (8); Broberg, A. (7); Siddiqui, AJ (7); Wolk, Alicja (6); Alhamdow, Ayman (6); Wahlberg, Karin (6); Dennis, J (5); Peterlongo, P (5); Anton-Culver, H (5); Giles, GG (5); Milne, RL (5); Orr, N (5); Southey, MC (5); Hamann, U (5); Fasching, PA (5); Ekici, AB (5); Beckmann, MW (5); Couch, FJ (5); Lambrechts, D (5); Chang-Claude, J (5); Haiman, CA (5); Simard, J (5); Hooning, MJ (5); Lubinski, J (5); Nevanlinna, H (5); Dork, T (5); Chenevix-Trench, G (5); Easton, DF (5); Pharoah, PDP (5); Vahter, Marie (5); Khusnutdinova, E (5); Schmutzler, RK (5); Beesley, J (5); Hunter, DJ (5); Whittemore, AS (5); Kippler, Maria (5); Broberg, AM (5); Engström, Karin (5); Broberg, K. (5); Schoemaker, MJ (5); show less...

University: Karolinska Institutet (65); University of Gothenburg (45); Lund University (39); Uppsala University (15); Umeå University (6); Royal Institute of Technology (4); show more...; Chalmers University of Technology (4); Stockholm University (2); Örebro University (2); Linköping University (1); Jönköping University (1); Mid Sweden University (1); RISE (1); Högskolan Dalarna (1); show less...

Language: English (114); Swedish (2); German (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (46); Social Sciences (33); Natural sciences (10); Engineering and Technology (6); Agricultural Sciences (2)

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