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Search: WFRF:(Buivydaite Ruta)

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  • Rowe, Kirsten, et al. (author)
  • Executive function in HIV-affected children and adolescents : a systematic review and meta-analyses
  • 2021
  • In: AIDS Care. - : Routledge. - 0954-0121 .- 1360-0451. ; 33:7, s. 833-857
  • Journal article (peer-reviewed)abstract
    • This review aimed to determine: whether EF is affected in children and adolescents (2–24-years-old) with perinatal HIV infection, perinatal HIV exposure without infection, and behaviourally acquired HIV. A systematic review (PROSPERO number: CRD42017067813) was conducted using 11 electronic databases (01.01.1981–09.07.2019) and 8 conference websites. Primary quantitative studies with EF scores on cognitive tasks and/or behavioural report measures were included. Meta-analyses were performed by EF subtype and subpopulations compared. 1789 records were found. Sixty-one studies were included in the narrative synthesis; 32 (N = 7884 participants) were included in meta-analyses. There was a distinct pattern of reduced EF in those with perinatal HIV infection on antiretroviral therapy compared to controls: pooled effect sizes were largest for verbal and visuospatial working memory, with smaller effects on planning, inhibitory control and set-shifting. Data were limited for other HIV-affected subpopulations. Perinatal HIV infection is associated with reduced EF with varying effect sizes for the different EF subtypes.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Wagner, Ryan G. (1)
Stein, Alan (1)
Scerif, Gaia (1)
Rowe, Kirsten (1)
Buivydaite, Ruta (1)
Heinsohn, Torben (1)
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Rahimzadeh, Mana (1)
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University
Umeå University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
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