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1.	Schwarzer, M., et al. (author) Microbe-mediated intestinal NOD2 stimulation improves linear growth of undernourished infant mice 2023 In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 379:6634 Journal article (peer-reviewed)abstract The intestinal microbiota is known to influence postnatal growth. We previously found that a strain of Lactiplantibacillus plantarum (strain LpWJL) buffers the adverse effects of chronic undernutrition on the growth of juvenile germ-free mice. Here, we report that LpWJLsustains the postnatal growth of malnourished conventional animals and supports both insulin-like growth factor-1 (IGF-1) and insulin production and activity. We have identified cell walls isolated from LpWJL, as well as muramyl dipeptide and mifamurtide, as sufficient cues to stimulate animal growth despite undernutrition. Further, we found that NOD2 is necessary in intestinal epithelial cells for LpWJL-mediated IGF-1 production and for postnatal growth promotion in malnourished conventional animals. These findings indicate that, coupled with renutrition, bacteria cell walls or purified NOD2 ligands have the potential to alleviate stunting.
2.	Erjavec, Nika, 1977, et al. (author) Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome 2013 In: Free Radical Biology and Medicine. - : Elsevier BV. - 0891-5849. ; 56, s. 9-16 Journal article (peer-reviewed)abstract The Saccharomyces cerevisiae homolog of the ATP-dependent Lon protease, Pim1p, is essential for

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Type of publication: journal article (2)

Type of content: peer-reviewed (2)

Author/Editor: Bulteau, A. L. (2); Nyström, Thomas, 196 ... (1); Schwarzer, M. (1); Kozakova, H. (1); Chamaillard, M (1); Vidal, H (1); show more...; Leulier, F. (1); Makki, Kassem (1); Camougrand, N (1); Lambert, A (1); Erjavec, Nika, 1977 (1); Bayot, A. (1); Gareil, M. (1); Friguet, B. (1); Peretti, N. (1); Brabec, T (1); Boneca, I. G. (1); Joly, A. (1); Gautam, U. K. (1); Srutkova, D. (1); Poinsot, P. (1); Novotna, T. (1); Geoffroy, S. (1); Courtin, P. (1); Hermanova, P. P. (1); Matos, R. C. (1); Landry, J. J. M. (1); Gerard, C. (1); Hudcovic, T. (1); Filipp, D. (1); Chapot-Chartier, M. ... (1); Sinkora, M. (1); De Vadder, F. (1); show less...

University: University of Gothenburg (2)

Language: English (2)

Research subject (UKÄ/SCB): Natural sciences (1); Medical and Health Sciences (1)

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