| 1. |
- Özçetin, Seda
(author)
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Life, death, and after life
- 2021
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Conference paper (peer-reviewed)abstract
- In Changing Things, Redström and Wiltse (2019) talk about how things have changed in their becoming throughout the history bringing us to the time of fluid assemblages. These dynamic beings have created new spatio-temporal ecologies. This moment looks at fluid assemblages and their impact in DRS community’s everyday lives. What kinds of things have emerged at our homes or workplaces (Life), what kinds of things have disappeared (Death), what kinds of things do we still keep but not use or have we repurposed (After Life)? What caused these transitions? How is our relationship with these things, how do we feel about them, what has changed?The moment invites the DRS community to create collages reflecting on these experiences by focusing on a selection of daily activities as listening to music, doing sports, cooking, maintaining wellbeing, etc. on a collective Miro board.
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| 2. |
- Maklakov, Alexei A, et al.
(author)
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Within-population variation in cytoplasmic genes affects female life span and aging in Drosophila melanogaster
- 2006
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In: Evolution. - : Wiley. - 0014-3820 .- 1558-5646. ; 60:10, s. 2081-2086
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Journal article (peer-reviewed)abstract
- It has been suggested that mitochondrial DNA (mtDNA) may play an important role in aging. Yet, few empirical studies have tested this hypothesis, partly because the degree of sequence polymorphism in mtDNA is assumed to be low. However, low sequence variation may not necessarily translate into low phenotypic variation. Here, we report an experiment that tests whether there is within-population variation in cytoplasmic genes for female longevity and senescence. To achieve this, we randomly selected 25 "mitochondrial founders" from a single, panmictic population of Drosophila melanogaster and used these founders to generate distinct "mt" lines in which we controlled for the nuclear background by successive backcrossing. Potential confounding effects of cytoplasmically transmitted bacteria were eliminated by tetracycline treatment. The mt lines were then assayed for differences in longevity, Gompertz intercept (frailty), and demographic rate of change in mortality with age (rate-of-senescence) in females. We found significant cytoplasmic effects on all three variables. This provides evidence that genetic variation in cytoplasmic genes, presumably mtDNA, contributes to variation in female mortality and aging.
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| 3. |
- Maklakov, Alexei A., et al.
(author)
-
Within-population variation in cytoplasmic genes affects female life span and aging in Drosophila melanogaster
- 2006
-
In: Evolution. - : The Society for the Study of Evolution. - 0014-3820 .- 1558-5646. ; 60:10, s. 2081-2086
-
Journal article (peer-reviewed)abstract
- It has been suggested that mitochondrial DNA (mtDNA) may play an important role in aging. Yet, few empirical studies have tested this hypothesis, partly because the degree of sequence polymorphism in mtDNA is assumed to be low. However, low sequence variation may not necessarily translate into low phenotypic variation. Here, we report an experiment that tests whether there is within-population variation in cytoplasmic genes for female longevity and senescence. To achieve this, we randomly selected 25 "mitochondrial founders" from a single, panmictic population of Drosophila melanogaster and used these founders to generate distinct "mt" lines in which we controlled for the nuclear background by successive backcrossing. Potential confounding effects of cytoplasmically transmitted bacteria were eliminated by tetracycline treatment. The mt lines were then assayed for differences in longevity, Gompertz intercept (frailty), and demographic rate of change in mortality with age (rate-of-senescence) in females. We found significant cytoplasmic effects on all three variables. This provides evidence that genetic variation in cytoplasmic genes, presumably mtDNA, contributes to variation in female mortality and aging.
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| 4. |
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| 5. |
- Simic, M., et al.
(author)
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Parameter Estimation of the Single-Dispersion Fractional Cole-Impedance Model With the Embedded Hardware
- 2023
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In: IEEE Sensors Journal. - : Institute of Electrical and Electronics Engineers (IEEE). - 1530-437X .- 1558-1748. ; 23:12, s. 12978-12987
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Journal article (peer-reviewed)abstract
- Bioimpedance modeling with equivalent electrical circuits has an important role in various biomedical applications, as it facilitates understanding of underlying physical and electrochemical processes in applications such as body composition measurements and assessment of clinical conditions. However, the estimation of model parameter values is not a straightforward task, especially when complex circuits with fractional-order components [e.g., constant phase elements (CPEs)] are used. In this article, we propose a low-complexity method for parameter estimation of the Cole-impedance model suitable for low-cost embedded hardware (e.g., 8-bit microcontrollers). Our approach uses only the measured real and imaginary impedance, without any specific software package/toolbox, or initial values provided by the user. The proposed method was validated with synthetic (noiseless and noisy) data and experimental right-side, hand-to-foot bioimpedance data from a healthy adult participant. Moreover, the proposed method was compared in terms of accuracy with the recently published relevant work and commercial Electrical Impedance Spectroscopy software (Bioimp 2.3.4). The performance evaluation in terms of complexity (suitable for deployment for the microcontroller-based platform with 256 kB of RAM and 16 MHz clock speed), execution time (18 s for the dataset with 256 points), and cost (< 25) confirms the proposed method in regards to reliable bioimpedance processing using embedded hardware.
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