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- Bradfute, Steven B., et al.
(author)
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ICTV Virus Taxonomy Profile: Hantaviridae 2024
- 2024
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In: Journal of General Virology. - : MICROBIOLOGY SOC. - 0022-1317 .- 1465-2099. ; 105:4
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Journal article (peer-reviewed)abstract
- Hantaviridae is a family for negative - sense RNA viruses with genomes of about 10.5-14.6 kb. These viruses are maintained in and/or transmitted by fish, reptiles, and mammals. Several orthohantaviruses can infect humans, causing mild, severe, and sometimes - fatal diseases. Hantavirids produce enveloped virions containing three single- stranded RNA segments with open reading frames that encode a nucleoprotein (N), a glycoprotein precursor (GPC), and a large (L) protein containing an RNAdirected RNA polymerase (RdRP) domain. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Hantaviridae, which is available at ictv.global/report/hantaviridae.
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- Kuhn, Jens H., et al.
(author)
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Pending Reorganization of Hantaviridae to Include Only Completely Sequenced Viruses: A Call to Action
- 2023
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In: Viruses. - : MDPI. - 1999-4915. ; 15:3
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Journal article (other academic/artistic)abstract
- The official classification of newly discovered or long-known unassigned viruses by the International Committee on Taxonomy of Viruses (ICTV) requires the deposition of coding-complete or -near-complete virus genome sequences in GenBank to fulfill a requirement of the taxonomic proposal (TaxoProp) process. However, this requirement is fairly new; thus, genomic sequence information is fragmented or absent for many already-classified viruses. As a result, taxon-wide modern phylogenetic analyses are often challenging, if not impossible. This problem is particularly eminent among viruses with segmented genomes, such as bunyavirals, which were frequently classified solely based on single-segment sequence information. To solve this issue for one bunyaviral family, Hantaviridae, we call on the community to provide additional sequence information for incompletely sequenced classified viruses by mid-June 2023. Such sequence information may be sufficient to prevent their possible declassification during the ongoing efforts to establish a coherent, consistent, and evolution-based hantavirid taxonomy.
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