| 1. |
- Sun, Xu, et al.
(författare)
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Elevated heparanase expression is associated with poor prognosis in breast cancer : a study based on systematic review and TCGA data
- 2017
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Ingår i: Oncotarget. - : IMPACT JOURNALS LLC. - 1949-2553. ; 8:26, s. 43521-43535
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Forskningsöversikt (refereegranskat)abstract
- Heparanase promotes tumorigenesis, angiogenesis, and metastasis. Here, we conducted a study based on systematic review and the Cancer Genome Atlas (TCGA) data that examined heparanase expression in clinical samples to determine its prognostic value. According to the meta-analysis and TCGA data, we found that heparanase expression was up-regulated in most breast cancer specimens, and elevated heparanase expression was associated with increased lymph node metastasis, larger tumor size, higher histological grade, and poor survival. These results suggest that targeting heparanase might improve treatments for breast cancer patients.
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| 2. |
- Luo, Shijian, et al.
(författare)
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RoamFab : A Design Tool for Reconfiguring Parameterized Mechanisms to 3D Models With Structural Optimization
- 2023
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Ingår i: International Journal of Human-Computer Interaction. - : Informa UK Limited. - 1044-7318 .- 1532-7590. ; 39:19, s. 3702-3716
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Tidskriftsartikel (refereegranskat)abstract
- Creating personalized 3D printing objects has become increasingly popular with the advance in end-user modeling tools and fabrication techniques. However, it remains challenging for novice makers to design and fabricate functional objects with mechanical motion such as linear or rotational. To empower users to add mechanical movements to their models for particular needs, we first investigate the commonly used 3D printable mechanisms and parameterize four mechanical primitives. We then provide a computational approach to reconfigure the mechanical primitives to user-provided 3D models, with an underlying structural optimization procedure according to a specified bending force. We further showcase a set of design examples and conduct a user study to demonstrate the potential of our approach in creating personalized functional artifacts.
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| 3. |
- Wang, Lin, et al.
(författare)
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Synthesis and high pressure induced amorphization of C60 nanosheets
- 2007
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Ingår i: Applied Physics Letters. - : AIP Publishing. - 0003-6951 .- 1077-3118. ; 91:10, s. 103112-
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Tidskriftsartikel (refereegranskat)abstract
- C-60 nanosheets with thicknesses in the nanometer range were synthesized by a simple method. Compared to bulk C-60, the lattice of the nanosheets is expanded by about 0.4%. In situ Raman spectroscopy and energy-dispersive x-ray diffraction under high pressures have been employed to study the structure of the nanosheets. The studies indicate that the bulk modulus of the C-60 nanosheets is significantly larger than that of bulk C-60. The C-60 cages in nanosheets can persist at pressures over 30 GPa, 3 GPa higher than for bulk C-60. These results suggest that C-60 crystals in even small size will be a potential candidate of superhard materials.
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| 4. |
- Wang, Yanan, et al.
(författare)
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SKIN+ : Fabricating Soft Fluidic User Interfaces for Enhancing On-Skin Experiences and Interactions
- 2018
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Ingår i: CHI EA '18, Extended Abstracts of the 2018 CHI Conference on Human Factors in Computing Systems. - New York, NY, USA : Association for Computing Machinery (ACM). - 9781450356213
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Konferensbidrag (refereegranskat)abstract
- Human skin is the largest organ on our body not only senses and external environment. A growing number of researchers devote themselves to design seamless interfaces directly on skin. In this late-breaking work, we propose a novel way for creating dynamic 2.5D skin textures, called SKIN+, a soft fluidic mini-scale user interface by introducing fluidic actuation. We have created four swatches with different pre-defined textures, topologies and structures to explore how this fluidic actuation system can benefit on-skin experiences and interactions. Our work details the intriguing experiences and interactions and future applications of on-skin wearables. Our work also extends the expressiveness, aesthetics and design space of soft fluidic interface as skin decoration and beauty technology.
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| 5. |
- Zhang, Jibin, et al.
(författare)
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A Multifunctional "Halide-Equivalent" Anion Enabling Efficient CsPb(Br/I)(3) Nanocrystals Pure-Red Light-Emitting Diodes with External Quantum Efficiency Exceeding 23%
- 2023
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Ingår i: Advanced Materials. - : WILEY-V C H VERLAG GMBH. - 0935-9648 .- 1521-4095. ; 35:8
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Tidskriftsartikel (refereegranskat)abstract
- Pure-red perovskite LEDs (PeLEDs) based on CsPb(Br/I)(3) nanocrystals (NCs) usually suffer from a compromise in emission efficiency and spectral stability on account of the surface halide vacancies-induced nonradiative recombination loss, halide phase segregation, and self-doping effect. Herein, a "halide-equivalent" anion of benzenesulfonate (BS-) is introduced into CsPb(Br/I)(3) NCs as multifunctional additive to simultaneously address the above challenging issues. Joint experiment-theory characterizations reveal that the BS- can not only passivate the uncoordinated Pb2+-related defects at the surface of NCs, but also increase the formation energy of halide vacancies. Moreover, because of the strong electron-withdrawing property of sulfonate group, electrons are expected to transfer from the CsPb(Br/I)(3) NC to BS- for reducing the self-doping effect and altering the n-type behavior of CsPb(Br/I)(3) NCs to near ambipolarity. Eventually, synergistic boost in device performance is achieved for pure-red PeLEDs with CIE coordinates of (0.70, 0.30) and a champion external quantum efficiency of 23.5%, which is one of the best value among the ever-reported red PeLEDs approaching to the Rec. 2020 red primary color. Moreover, the BS--modified PeLED exhibits negligible wavelength shift under different operating voltages. This strategy paves an efficient way for improving the efficiency and stability of pure-red PeLEDs.
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