↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Degos L) "

Search: WFRF:(Degos L)

Result 1-10 of 10

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Calabresi, PA, et al. (author) The incidence and significance of anti-natalizumab antibodies: results from AFFIRM and SENTINEL 2007 In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 69:14, s. 1391-1403 Journal article (peer-reviewed)
2.	van Wijk, RPJ, et al. (author) Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study 2020 In: Journal of critical care. - : Elsevier BV. - 1557-8615 .- 0883-9441. ; 59, s. 6-15 Journal article (peer-reviewed)
3.	Hudson, Thomas J., et al. (author) International network of cancer genome projects 2010 In: Nature. - : Springer Science and Business Media LLC. - 0028-0836 .- 1476-4687. ; 464:7291, s. 993-998 Journal article (peer-reviewed)abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate large-scale cancer genome studies in tumours from 50 different cancer types and/or subtypes that are of clinical and societal importance across the globe. Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
4.	Kappos, L, et al. (author) Placebo-controlled multicentre randomised trial of interferon beta-1b in treatment of secondary progressive multiple sclerosis. European Study Group on interferon beta-1b in secondary progressive MS 1998 In: Lancet (London, England). - 0140-6736. ; 352:9139, s. 1491-1497 Journal article (peer-reviewed)
5.	Rezoagli, E, et al. (author) Correction: High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI 2023 In: Intensive care medicine. - : Springer Science and Business Media LLC. - 1432-1238 .- 0342-4642. ; 49:2, s. 269-272 Journal article (other academic/artistic)
6.	Koken, MHM, et al. (author) The PML growth suppressor has an altered expression in human oncogenesis 1995 In: Oncogene. ; 10, s. 1315- Journal article (peer-reviewed)
7.	Ludwig, H, et al. (author) Management of disease-related anemia in patients with multiple myeloma or chronic lymphocytic leukemia: epoetin treatment recommendations 2002 In: The hematology journal : the official journal of the European Haematology Association. - : Springer Science and Business Media LLC. - 1466-4860. ; 3:3, s. 121-30 Journal article (peer-reviewed)
8.	Osterborg, A, et al. (author) Phase II multicenter study of human CD52 antibody in previously treated chronic lymphocytic leukemia. European Study Group of CAMPATH-1H Treatment in Chronic Lymphocytic Leukemia 1997 In: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. - 0732-183X. ; 15:4, s. 1567-1574 Journal article (peer-reviewed)
9.	Marcellin, P, et al. (author) EASL International Consensus Conference on Hepatitis C - Paris, 26-27 February 1999 - Consensus statement (Reprinted from Journal of Hematology, vol 30, pg 956-961, 1999) 1999 In: JOURNAL OF HEPATOLOGY. - 0168-8278. ; 31, s. 3-8 Journal article (other academic/artistic)
10.	Van Steenwinckel, Juliette, et al. (author) Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain. 2019 In: Brain : a journal of neurology. - : Oxford University Press (OUP). - 1460-2156. ; 142:12, s. 3806-3833 Journal article (peer-reviewed)abstract Microglia of the developing brain have unique functional properties but how their activation states are regulated is poorly understood. Inflammatory activation of microglia in the still-developing brain of preterm-born infants is associated with permanent neurological sequelae in 9 million infants every year. Investigating the regulators of microglial activation in the developing brain across models of neuroinflammation-mediated injury (mouse, zebrafish) and primary human and mouse microglia we found using analysis of genes and proteins that a reduction in Wnt/β-catenin signalling is necessary and sufficient to drive a microglial phenotype causing hypomyelination. We validated in a cohort of preterm-born infants that genomic variation in the Wnt pathway is associated with the levels of connectivity found in their brains. Using a Wnt agonist delivered by a blood-brain barrier penetrant microglia-specific targeting nanocarrier we prevented in our animal model the pro-inflammatory microglial activation, white matter injury and behavioural deficits. Collectively, these data validate that the Wnt pathway regulates microglial activation, is critical in the evolution of an important form of human brain injury and is a viable therapeutic target.

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-10 of 10

Refine your search

Type of publication: journal article (10)

Type of content: peer-reviewed (8); other academic/artistic (2)

Author/Editor: Richter, S. (2); Ercole, A (2); Williams, G. (2); Osterborg, A (2); Hutchinson, M (2); Roe, C (2); show more...; Manara, A. (2); Comi, G (2); Nelson, D. (2); Fredrikson, S (2); Beretta, L (2); McMahon, C (2); Hutchinson, PJ (2); Rossi, S (2); Farkkila, M (2); Roise, O (2); Bellander, BM (2); Thomas, M (2); Gold, R. (2); Zeiler, FA (2); Gupta, D. (2); Radoi, A (2); ROSSI, P (2); Andelic, N (2); Citerio, G (2); Wolf, S (2); Helbok, R (2); Stoll, G (2); Tintore, M (2); Blanc, S (2); Kovacs, N (2); Buttinelli, C (2); Jankowski, S. (2); Edan, G (2); Clanet, M (2); Depreitere, B. (2); Grossi, F (2); Rhodes, J. (2); Cooper, JD (2); Raj, R (2); Gunther, A (2); Sahuquillo, J (2); Stocchetti, N (2); Brochet, B (2); Hartung, HP (2); Kappos, L (2); Czosnyka, M (2); Smielewski, P (2); Cabeleira, M (2); Menon, DK (2); show less...

University: Karolinska Institutet (8); Uppsala University (2); University of Gothenburg (1); Umeå University (1); Royal Institute of Technology (1); Örebro University (1); show more...; Lund University (1); show less...

Language: English (10)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view