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1.	Bainbridge, Wilma A., et al. (author) Memorability of photographs in subjective cognitive decline and mild cognitive impairment : Implications for cognitive assessment 2019 In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. - : Wiley. - 2352-8729. ; 11, s. 610-618 Journal article (peer-reviewed)abstract Introduction: Impaired long-term memory is a defining feature of mild cognitive impairment (MCI). We tested whether this impairment is item specific, limited to some memoranda, whereas some remain consistently memorable. Methods: We conducted item-based analyses of long-term visual recognition memory. Three hundred ninety-four participants (healthy controls, subjective cognitive decline [SCD], and MCI) in the multicentric DZNE-Longitudinal Cognitive Impairment and Dementia Study (DELCODE) were tested with images from a pool of 835 photographs. Results: We observed consistent memorability for images in healthy controls, SCD, and MCI, predictable by a neural network trained on another healthy sample. Looking at memorability differences between groups, we identified images that could successfully categorize group membership with higher success and a substantial image reduction than the original image set. Discussion: Individuals with SCD and MCI show consistent memorability for specific items, while other items show significant diagnosticity. Certain stimulus features could optimize diagnostic assessment, while others could support memory.

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Type of publication: journal article (1)

Type of content: peer-reviewed (1)

Author/Editor: Berron, David (1); Fliessbach, Klaus (1); Wiltfang, Jens (1); Bainbridge, Wilma A. (1); Schütze, Hartmut (1); Cardenas-Blanco, Art ... (1); show more...; Metzger, Coraline (1); Dobisch, Laura (1); Bittner, Daniel (1); Glanz, Wenzel (1); Spottke, Annika (1); Rudolph, Janna (1); Brosseron, Frederic (1); Buerger, Katharina (1); Janowitz, Daniel (1); Heneka, Michael (1); Laske, Christoph (1); Buchmann, Martina (1); Peters, Oliver (1); Diesing, Dominik (1); Li, Siyao (1); Priller, Josef (1); Spruth, Eike Jakob (1); Altenstein, Slawek (1); Schneider, Anja (1); Kofler, Barbara (1); Teipel, Stefan (1); Kilimann, Ingo (1); Bartels, Claudia (1); Wolfsgruber, Steffen (1); Wagner, Michael (1); Jessen, Frank (1); Baker, Chris I. (1); Düzel, Emrah (1); show less...

Language: English (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

Year: 2019 (1)

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