SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Edlund U.) "

Search: WFRF:(Edlund U.)

  • Result 1-10 of 34
Sort/group result
   
EnumerationReferenceCoverFind
1.
  •  
2.
  •  
3.
  •  
4.
  • Jiang, X., et al. (author)
  • Shared heritability and functional enrichment across six solid cancers
  • 2019
  • In: Nature Communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 10
  • Journal article (peer-reviewed)abstract
    • Quantifying the genetic correlation between cancers can provide important insights into the mechanisms driving cancer etiology. Using genome-wide association study summary statistics across six cancer types based on a total of 296,215 cases and 301,319 controls of European ancestry, here we estimate the pair-wise genetic correlations between breast, colorectal, head/neck, lung, ovary and prostate cancer, and between cancers and 38 other diseases. We observed statistically significant genetic correlations between lung and head/neck cancer (r(g) = 0.57, p = 4.6 x 10(-8)), breast and ovarian cancer (r(g) = 0.24, p = 7 x 10(-5)), breast and lung cancer (r(g) = 0.18, p = 1.5 x 10(-6)) and breast and colorectal cancer (r(g) = 0.15, p = 1.1 x 10(-4)). We also found that multiple cancers are genetically correlated with non-cancer traits including smoking, psychiatric diseases and metabolic characteristics. Functional enrichment analysis revealed a significant excess contribution of conserved and regulatory regions to cancer heritability. Our comprehensive analysis of cross-cancer heritability suggests that solid tumors arising across tissues share in part a common germline genetic basis.
  •  
5.
  •  
6.
  •  
7.
  • Alexanderson, K, et al. (author)
  • Ska socialmedicinen avskaffas?
  • 2002
  • In: Socialmedicinsk tidskrift. ; 79, s. 388-
  • Journal article (other academic/artistic)
  •  
8.
  •  
9.
  •  
10.
  • Edlund, Christer, 1962, et al. (author)
  • Sacral nerve stimulation for refractory urge symptoms in elderly patients.
  • 2004
  • In: Scand J Urol Nephrol. - : Informa UK Limited. ; 38:2, s. 131-5
  • Journal article (peer-reviewed)abstract
    • OBJECTIVE: The presence of an overactive detrusor (OD) is becoming more prevalent in the elderly and may severely influence the social life and activities of daily living in the senior, otherwise healthy, person. There is a marked age-dependent increase in OD above the age of 65 years, which is mainly attributed to dysfunction, with loss of voluntary control, of the micturition reflex and decreased perception of bladder fullness. MATERIAL AND METHODS: Herein, we evaluate the outcome of sacral nerve stimulation in five patients aged >65 years derived from a large, multinational, randomized, prospective study. RESULTS: The effect on symptoms was excellent in two subjects. There was a moderate improvement in another subject and a variable but eventually small effect in the remaining two patients. The results appeared to be more favourable in younger patients. CONCLUSION: Our findings suggest that the outcome of sacral nerve stimulation is more unpredictable in the elderly, a fact that should be considered when counselling the patient. However, it should be remembered that, even for the older, active person, urge incontinence may have a severe impact on quality of life and that the majority of patients treated with an implant will benefit from this treatment.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-10 of 34
Type of publication
journal article (26)
conference paper (6)
research review (1)
book chapter (1)
Type of content
peer-reviewed (29)
other academic/artistic (4)
pop. science, debate, etc. (1)
Author/Editor
Li, L. (5)
Zheng, W. (5)
Brenner, H (5)
White, E (5)
Edlund, C (5)
Chang-Claude, J (5)
show more...
Casey, G (5)
Peters, U (5)
Kim, J. (4)
Thomas, D. (4)
Moreno, V (4)
Lindblom, A (4)
Hampe, J (4)
Le Marchand, L (4)
Woods, M (4)
Albanes, D (4)
Weinstein, S (4)
Hsu, L (4)
Gago-Dominguez, M. (4)
Sundqvist, B. (4)
Rennert, G. (4)
Lejbkowicz, F. (4)
Offit, K. (4)
Hoffmeister, M (4)
Shu, XO (3)
Hall, P (3)
Czene, K (3)
Johansson, M (3)
LINDBERG, B (3)
Wolk, A (3)
Svensson, C (3)
Muir, K (3)
Fletcher, O (3)
Garcia-Closas, M (3)
Nevanlinna, H (3)
Meindl, A (3)
Kraft, P (3)
Gallinger, S (3)
Jenkins, M (3)
Gronberg, H (3)
Soldatov, Alexander (3)
Kote-Jarai, Z (3)
Lindstrom, S (3)
Wiklund, F (3)
Stefansson, K (3)
Risch, A. (3)
Edlund, K. (3)
Caporaso, N (3)
Jacobsson, P (3)
Bezieau, S (3)
show less...
University
Karolinska Institutet (15)
Uppsala University (8)
University of Gothenburg (7)
Umeå University (6)
Luleå University of Technology (4)
Lund University (4)
show more...
Chalmers University of Technology (4)
Royal Institute of Technology (2)
RISE (1)
show less...
Language
English (32)
Swedish (2)
Research subject (UKÄ/SCB)
Medical and Health Sciences (8)
Natural sciences (4)
Engineering and Technology (4)
Social Sciences (1)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view