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Search: WFRF:(Fan Yuebo)

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1.
  • Zhu, Huilin, et al. (author)
  • Atypical prefrontal cortical responses to joint/non-joint attention in children with autism spectrum disorder (ASD) : A functional near-infrared spectroscopy study
  • 2015
  • In: Biomedical Optics Express. - 2156-7085. ; 6:3, s. 690-701
  • Journal article (peer-reviewed)abstract
    • Autism spectrum disorder (ASD) is a neuro-developmental disorder, characterized by impairments in one's capacity for joint attention. In this study, functional near-infrared spectroscopy (fNIRS) was applied to study the differences in activation and functional connectivity in the prefrontal cortex between children with autism spectrum disorder (ASD) and typically developing (TD) children. 21 ASD and 20 TD children were recruited to perform joint and non-joint attention tasks. Compared with TD children, children with ASD showed reduced activation and atypical functional connectivity pattern in the prefrontal cortex during joint attention. The atypical development of left prefrontal cortex might play an important role in social cognition defects of children with ASD.
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2.
  • Zhu, Huilin, et al. (author)
  • Reduced interhemispheric functional connectivity of children with autism spectrum disorder : evidence from functional near infrared spectroscopy studies
  • 2014
  • In: Biomedical Optics Express. - 2156-7085. ; 5:4, s. 1262-1274
  • Journal article (peer-reviewed)abstract
    • Autism spectrum disorder (ASD) is a neuro-developmental disorder, which has been associated with atypical neural synchronization. In this study, functional near infrared spectroscopy (fNIRS) was used to study the differences in functional connectivity in bilateral inferior frontal cortices (IFC) and bilateral temporal cortices (TC) between ASD and typically developing (TD) children between 8 and 11 years of age. As the first report of fNIRS study on the resting state functional connectivity (RSFC) in children with ASD, ten children with ASD and ten TD children were recruited in this study for 8 minute resting state measurement. Compared to TD children, children with ASD showed reduced interhemispheric connectivity in TC. Children with ASD also showed significantly lower local connectivity in bilateral temporal cortices. In contrast to TD children, children with ASD did not show typical patterns of symmetry in functional connectivity in temporal cortex. These results support the feasibility of using the fNIRS method to assess atypical functional connectivity of cortical responses of ASD and its potential application in diagnosis.
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  • Result 1-2 of 2
Type of publication
journal article (2)
Type of content
peer-reviewed (2)
Author/Editor
He, Sailing (2)
Huang, Dan (2)
Zhu, Huilin (2)
Fan, Yuebo (2)
Li, Jun (1)
Li, Xinge (1)
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Guo, Huan (1)
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University
Royal Institute of Technology (2)
Language
English (2)
Research subject (UKÄ/SCB)
Natural sciences (2)
Medical and Health Sciences (1)

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