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  • Broussalis, Adriana M., et al. (author)
  • First cyclotide from Hybanthus (Violaceae)
  • 2001
  • In: Phytochemistry. - : Elsevier. - 0031-9422 .- 1873-3700. ; 58:1, s. 47-51
  • Journal article (peer-reviewed)abstract
    • Hypa A, a novel macrocyclic polypeptide containing 30 amino acid residues, has been isolated from the n-butanol extract of the Argentine plant Hybanthus parviflorus. The sequence, cyclo-(SCVYIPCTITALLGCSCKNKVCYNGIPCAE), was determined by automated Edman degradation, quantitative amino acid analysis and nanospray MS/MS2. Three intramolecular disulfide bridges stabilize the cyclic peptide backbone of hypa A. Using these structural features to classify the peptide as a cyclotide, we extended the distribution of that substance class to a new genus, and now propose a uniform nomenclature for cyclotides.
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  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Göransson, Ulf (1)
Broussalis, Adriana ... (1)
Coussio, Jorge D. (1)
Ferraro, Graciela (1)
Martino, Virginia (1)
Claeson, Per (1)
University
Uppsala University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Medical and Health Sciences (1)
Year
2001 (1)

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