SwePub
Sök i SwePub databas

  Extended search

Träfflista för sökning "WFRF:(Fischöder Thomas) "

Search: WFRF:(Fischöder Thomas)

  • Result 1-1 of 1
Sort/group result
   
EnumerationReferenceCoverFind
1.
  • Behren, Sandra, et al. (author)
  • Fucose binding motifs on mucin core glycopeptides impact bacterial lectin recognition
  • 2023
  • In: Angewandte Chemie International Edition. - 1433-7851 .- 1521-3773. ; 62:32
  • Journal article (peer-reviewed)abstract
    • Mucin glycoproteins are essential components of the mucosal barrier, which protects the host from pathogens. Throughout evolution, bacteria have developed strategies to modulate and penetrate this barrier, and cause virulence by interacting with mucin O-glycans at the epithelial cell-surface. O-fucosylated glycan epitopes on mucins are key ligands of many bacterial lectins. Here, a chemoenzymatic synthesis strategy is described to prepare a library of fucosylated mucin core glycopeptides to enable studies of mucin-interacting and fucose-binding bacterial lectins. Glycan cores with biologically important Lewis and H-antigens were prepared decorating the peptide backbone at different sites and densities. The fucosylated mucin glycopeptides were applied in microarray binding studies to explore the importance of glycan core and peptide backbone presentation of these antigens in binding interactions with the P. aeruginosa lectin LecB and the C. difficile toxin A.
  •  
Skapa referenser, mejla, bekava och länka
  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Schorlemer, Manuel (1)
Westerlind, Ulrika (1)
Behren, Sandra (1)
Yu, Jin (1)
Pett, Christian (1)
Heine, Viktoria (1)
show more...
Elling, Lothar (1)
Fischöder, Thomas (1)
show less...
University
Umeå University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2023 (1)

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view