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Search: WFRF:(Ganowiak Katarzyna)

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  • Ganowiak, Katarzyna, et al. (author)
  • Fibrils from Synthetic Amyloid-Related Peptides Enhance Development of Experimental AA-Amyloidosis in Mice
  • 1994
  • In: Biochemical and Biophysical Research Communications - BBRC. - : Elsevier BV. - 0006-291X .- 1090-2104. ; 199:1, s. 306-312
  • Journal article (peer-reviewed)abstract
    • Amyloid enhancing factor is an incompletely characterized activity of extracts from many amyloid-containing tissues and which greatly shortens the preamyloidotic phase during experimental induction of AA-amyloidosis. In this communication we show that amyloid-like fibrils made in vitro from synthetic peptides, corresponding to segments of amyloid fibril proteins, have amyloid enhancing factor-like activity. Thus, there is a possibility that amyloid enhancing factor activity depends on small fibrils serving as nucleation centers for fibril elongation.
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Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Hultman, Per (1)
Westermark, Per (1)
Gustavsson, Åsa (1)
Engström, Ulla (1)
Ganowiak, Katarzyna (1)
University
Linköping University (1)
Language
English (1)
Year

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