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- Goyvaerts, V, et al.
(author)
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Fluorescent SAM analogues for methyltransferase based DNA labeling
- 2020
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In: Chemical communications (Cambridge, England). - : Royal Society of Chemistry (RSC). - 1364-548X .- 1359-7345. ; 56:22, s. 3317-3320
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Journal article (peer-reviewed)abstract
- In this work, the preparation of new S-adenosyl-l-methionine (SAM) analogues for sequence specific DNA labeling is evaluated. Fluorescent cofactors were synthesized and their applicability in methyltransferase based optical mapping is demonstrated.
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