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Träfflista för sökning "WFRF:(Guo ZG) "

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1.	Jakobsson, J., et al. (author) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 2021 In: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 17:1, s. 1-382 Journal article (peer-reviewed)
2.	Ahmad, T, et al. (author) Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries 2016 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 117:5, s. 601- Journal article (peer-reviewed)
3.	Ahmad, T, et al. (author) In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study 2017 In: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. - : Elsevier BV. - 1532-2157 .- 0748-7983. ; 43:12, s. 2324-2332 Journal article (peer-reviewed)
4.	Ahmad, T, et al. (author) Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: a 7-day cohort study of elective surgery 2017 In: British journal of anaesthesia. - : Elsevier BV. - 1471-6771 .- 0007-0912. ; 119:2, s. 258-266 Journal article (peer-reviewed)
5.	Zhang, J, et al. (author) Inhibition of miR-1193 leads to synthetic lethality in glioblastoma multiforme cells deficient of DNA-PKcs 2020 In: Cell death & disease. - : Springer Science and Business Media LLC. - 2041-4889. ; 11:7, s. 602- Journal article (peer-reviewed)abstract Glioblastoma multiforme (GBM) is the most malignant primary brain tumor and has the highest mortality rate among cancers and high resistance to radiation and cytotoxic chemotherapy. Although some targeted therapies can partially inhibit oncogenic mutation-driven proliferation of GBM cells, therapies harnessing synthetic lethality are ‘coincidental’ treatments with high effectiveness in cancers with gene mutations, such as GBM, which frequently exhibits DNA-PKcs mutation. By implementing a highly efficient high-throughput screening (HTS) platform using an in-house-constructed genome-wide human microRNA inhibitor library, we demonstrated that miR-1193 inhibition sensitized GBM tumor cells with DNA-PKcs deficiency. Furthermore, we found that miR-1193 directly targets YY1AP1, leading to subsequent inhibition of FEN1, an important factor in DNA damage repair. Inhibition of miR-1193 resulted in accumulation of DNA double-strand breaks and thus increased genomic instability. RPA-coated ssDNA structures enhanced ATR checkpoint kinase activity, subsequently activating the CHK1/p53/apoptosis axis. These data provide a preclinical theory for the application of miR-1193 inhibition as a potential synthetic lethal approach targeting GBM cancer cells with DNA-PKcs deficiency.
6.	Cheng, G, et al. (author) Extensive diversification of IgH subclass-encoding genes and IgM subclass switching in crocodilians 2013 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 4, s. 1337- Journal article (peer-reviewed)
7.	Cheng, Q, et al. (author) A population-based survey of multiple sclerosis in Shanghai, China 2007 In: Neurology. - : Ovid Technologies (Wolters Kluwer Health). - 1526-632X .- 0028-3878. ; 68:18, s. 1495-1500 Journal article (peer-reviewed)
8.	Cheng, XJ, et al. (author) Associations of MRI-lesions and clinical features with disability in Chinese patients with multiple sclerosis 2013 In: NEUROLOGY ASIA. - 1823-6138. ; 18:4, s. 391-399 Journal article (other academic/artistic)
9.	Cheng, XJ, et al. (author) Associations of MRI-lesions and clinical features with disability in Chinese patients with multiple sclerosis 2010 In: EUROPEAN JOURNAL OF NEUROLOGY. - 1351-5101. ; 17, s. 486-486 Conference paper (other academic/artistic)
10.	Guo, JP, et al. (author) A replication study confirms the association of dendritic cell immunoreceptor (DCIR) polymorphisms with ACPA - negative RA in a large Asian cohort 2012 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 7:7, s. e41228- Journal article (peer-reviewed)

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Result 1-10 of 27

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Type of publication: journal article (26); conference paper (1)

Type of content: peer-reviewed (24); other academic/artistic (3)

Author/Editor: Yang, Y. (7); Liu, X (6); Xu, L. (6); Sun, Y (6); Liu, Y. (5); Wang, J. (5); show more...; Zhang, J. (5); Zhang, Y. (5); Cao, Y (5); Wang, L (5); Ali, M (5); Chen, S. (4); Li, B. (4); Liu, B. (4); Sanchez, A. (4); Silva, J. (4); Wang, F. (4); Zhang, H. (4); Zhang, L. (4); Zhao, L. (4); Li, J. (4); Kumar, S (4); Martin, S. (4); Liu, Q. (4); Wang, D. (4); Wang, Z. (4); Singh, A (4); Chen, Z. (4); Zhou, J. (4); Yang, L. (4); Yang, J. (4); Jin, H. (4); Ye, H. (4); Huang, S. (4); Harris, J. (4); Chen, Q. (4); Wu, J (4); Zhao, S (4); Rao, R (4); Shen, CY (4); Gao, H. (4); Lee, C. (4); Jones, C (4); Bernard, A (4); Zhang, XL (4); Chen, YJ (4); Huang, CS (4); Zhang, XY (4); Zhang, M (4); Chen, R (4); show less...

University: Karolinska Institutet (27); Linköping University (2); Lund University (2); Umeå University (1); Stockholm University (1); Swedish University of Agricultural Sciences (1)

Language: English (27)

Research subject (UKÄ/SCB): Medical and Health Sciences (5); Natural sciences (1)

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