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Träfflista för sökning "WFRF:(Gustavsson Å) "

Search: WFRF:(Gustavsson Å)

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  • Gustavsson, B., et al. (author)
  • Electron gyroharmonic effects in ionization and electron acceleration during high-frequency pumping in the ionosphere
  • 2006
  • In: Physical Review Letters. - 0031-9007 .- 1079-7114. ; 97:19, s. 195002-
  • Journal article (peer-reviewed)abstract
    • Optical emissions and incoherent scatter radar data obtained during high-frequency electromagnetic pumping of the ionospheric plasma from the ground give data on electron energization in an energy range from 2 to 100 eV. Optical emissions at 4278 angstrom from N-2(+) that require electrons with energies above the 18 eV ionization energy give the first images ever of pump-induced ionization of the thermosphere. The intensity at 4278 angstrom is asymmetric around the ionospheric electron gyroharmonic, being stronger above the gyroresonance. This contrasts with emissions at 6300 angstrom from O(D-1) and of electron temperature enhancements, which have minima at the gyroharmonic but have no apparent asymmetry. This direct evidence of pump-induced ionization contradicts previous indirect evidence, which indicated that ionization is most efficiently produced when the pump frequency was below the gyroharmonic.
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  • Ma, Zhi, et al. (author)
  • Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide
  • 2001
  • In: Amyloid. - : Informa UK Limited. - 1350-6129 .- 1744-2818. ; 8, s. 242-
  • Journal article (peer-reviewed)abstract
    • Islet amyloid polypeptide (IAPP, “amylin”) is the amyloid-fibril-forming polypeptide in the islets of Langerhans associated with type 2 diabetes mellitus. A missense mutation in the IAPP gene associated with early-onset type 2 diabetes has been identified in the Japanese population. This mutation results in a glycine for serine substitution at position 20 of the mature IAPP molecule. Whether or not formation of islet amyloid with resulting destruction of islet tissue is the cause of this diabetes is yet not known. The present in vitro study was performed in order to investigate any influence of the amino acid substitution on the fibril formation capacity. Synthetic full-length wild type (lAPPwt) and mutant (IAPPS20G) as well as corresponding truncated peptides (position 18-29) were dissolved in dimethylsulfoxide (DMSO) or in 10% acetic acid at a concentration of 10 mg/mL and their fibril forming capacity was checked by Congo red staining, electron microscopy, a Congo red affinity assay and Thioflavine T fluorometric assay. It was found that full-length and truncated IAPPS20G both formed more amyloid-like fibrils and did this faster compared to IAPPwt. The fibril morphology differed slightly between the preparations. Conclusion: The amino acid substitution (S20G) is situated close to the region of the IAPP molecule implicated in the IAPP fibrillogenesis. The significantly increased formation of amyloid-like fibrils by IAPPS20G is highly interesting and may be associated with an increased islet amyloid formation in vivo and of fundamental importance in the pathogenesis of this specific form of diabetes.
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  • Result 1-10 of 16
Type of publication
journal article (7)
book chapter (4)
other publication (2)
conference paper (2)
reports (1)
Type of content
peer-reviewed (8)
other academic/artistic (7)
pop. science, debate, etc. (1)
Author/Editor
Westermark, P (6)
Gustavsson, Å (6)
Ando, Y (2)
Gustavsson, G (2)
Andò, E (2)
Gustavsson, Leif (1)
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Sakamoto, H. (1)
Stridsberg, M (1)
Dellborg, M (1)
Negi, A. (1)
Yamashita, T. (1)
Herlitz, Johan (1)
Gustavsson, B (1)
Kato, K. (1)
Swedberg, K (1)
Wilander, E (1)
Gustavsson, L (1)
Gustavsson, JP (1)
Westermark, Gunilla, ... (1)
Terazaki, H (1)
Bergström, G. (1)
Lomsky, M (1)
LUNDQVIST, G (1)
Ma, Z (1)
Samuelson, Gösta, 19 ... (1)
Lundmark, K (1)
Ando, M (1)
Suhr, O (1)
Ohlsson, P-I (1)
Obayashi, K (1)
Svensson, Å. (1)
Långström, B. (1)
Ekelund, Nils, 1956- (1)
Peterson, Ulla (1)
Sandgren, O (1)
Ma, Zhi (1)
Hjalmarson, Å (1)
Engström, Ulla (1)
Bruce, Å (1)
Sjölin, S (1)
Hagman, U (1)
Wängberg, S. -Å (1)
Leyser, Thomas (1)
Rietveld, M. T. (1)
Risenfors, M (1)
Aso, T (1)
Gustavsson, Bengt Ov ... (1)
Eriksson, HB (1)
Öberg, K. (1)
GOTTFRIDSSON, C (1)
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University
Uppsala University (10)
Linnaeus University (2)
University West (1)
Linköping University (1)
Malmö University (1)
Mid Sweden University (1)
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University of Borås (1)
Karlstad University (1)
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Language
English (14)
Swedish (2)
Research subject (UKÄ/SCB)
Natural sciences (2)
Medical and Health Sciences (2)
Engineering and Technology (1)

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