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1.	Alström, P, et al. (author) [Ritual poisoning with a hallucinogenic plant. Guidelines in severe poisoning with anticholinergics] 1999 In: Lakartidningen. - 0023-7205. ; 96:50, s. 5612-4 Journal article (peer-reviewed)
2.	Bilberg, Johan, 1646-1717 (author) Ex consensu et adprobatione amplissimi collegii philosophici ... sub præsidio ... Dn. Joannis Bilberg ... dissertationem metaphysicam de univocatione et analogia entis publice ventilandam proponit Laurentz Höjer Wesm. antiq. patr. & phil. stud. in audit. Gustav. maj. ad diem [ ] anni M DC. LXXXVII 1687 Doctoral thesis (other academic/artistic)
3.	Efvergren, M, et al. (author) [Case report. Herpes simplex encephalitis--a life-threatening but curable condition] 1995 In: Lakartidningen. - 0023-7205. ; 92:11, s. 1124-6 Journal article (peer-reviewed)
4.	Forsberg, M, et al. (author) [No support for lipid therapy as an effective antidote in acute intoxication. A systematic literature review and analysis of 114 case reports] 2015 In: Lakartidningen. - 1652-7518. ; 112 Journal article (peer-reviewed)
5.	Håkansson, Anne Kristin, et al. (author) Preface 2013 In: Smart Innovation, Systems and Technologies. - 2190-3018 .- 2190-3026. ; 22 Journal article (peer-reviewed)
6.	Håkansson, Anne, 1963-, et al. (author) Sustainability in energy and buildings 2013 In: Sustainability in Energy and Buildings. - Berlin Heidelberg : Springer Berlin/Heidelberg. - 9783642366444 ; , s. I-1110 Book chapter (peer-reviewed)
7.	Höjer, J, et al. (author) [The first case of rabies in Sweden in 26 years. Inform travellers abroad about risks and treatment following suspected infection] 2001 In: Lakartidningen. - 0023-7205. ; 98:11, s. 1216-20 Journal article (peer-reviewed)
8.	Karlson-Stiber, C, et al. (author) [Toxic pneumonitis in a hockey player. Poisonous gases are produced by ice machines] 1996 In: Lakartidningen. - 0023-7205. ; 93:43, s. 3808-3811 Journal article (peer-reviewed)
9.	Romanson, Henrik Wilhelm, 1776-1853 (author) Myologiska dissectioner eller afhandling om musklerne i menniskokroppen ... under inseende af Henr. Wilh. Romanson ... för medicinska graden till offentelig granskning utgifne af Axel Höjer af Upl. nat. På medicinska lärosalen den 1 juni 1833 p. v. t., XI st 1833 Doctoral thesis (other academic/artistic)
10.	Sahlén, Pelin, et al. (author) Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis– and psoriasis-associated genes 2020 In: Journal of Allergy and Clinical Immunology. - : Mosby Inc.. - 0091-6749 .- 1097-6825. Journal article (peer-reviewed)abstract Background: Hundreds of variants associated with atopic dermatitis (AD) and psoriasis, 2 common inflammatory skin disorders, have previously been discovered through genome-wide association studies (GWASs). The majority of these variants are in noncoding regions, and their target genes remain largely unclear. Objective: We sought to understand the effects of these noncoding variants on the development of AD and psoriasis by linking them to the genes that they regulate. Methods: We constructed genomic 3-dimensional maps of human keratinocytes during differentiation by using targeted chromosome conformation capture (Capture Hi-C) targeting more than 20,000 promoters and 214 GWAS variants and combined these data with transcriptome and epigenomic data sets. We validated our results with reporter assays, clustered regularly interspaced short palindromic repeats activation, and examination of patient gene expression from previous studies. Results: We identified 118 target genes of 82 AD and psoriasis GWAS variants. Differential expression of 58 of the 118 target genes (49%) occurred in either AD or psoriatic lesions, many of which were not previously linked to any skin disease. We highlighted the genes AFG1L, CLINT1, ADO, LINC00302, and RP1-140J1.1 and provided further evidence for their potential roles in AD and psoriasis. Conclusions: Our work focused on skin barrier pathology through investigation of the interaction profile of GWAS variants during keratinocyte differentiation. We have provided a catalogue of candidate genes that could modulate the risk of AD and psoriasis. Given that only 35% of the target genes are the gene nearest to the known GWAS variants, we expect that our work will contribute to the discovery of novel pathways involved in AD and psoriasis.

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Type of publication: journal article (12); doctoral thesis (2); editorial proceedings (1); conference paper (1); book chapter (1)

Type of content: peer-reviewed (15); other academic/artistic (2)

Author/Editor: Höjer, Mattias (6); Höjer, J (5); Lange, S. (2); Höjer, Ingrid, 1953 (2); Mukherjee, A. (1); Forsberg, S (1); show more...; Kim, K. H. (1); Håkansson, Anne (1); Bradley, M (1); Nikamo, P (1); Sahlén, Pelin (1); Hilty, Lorenz (1); Håkansson, Anne, 196 ... (1); Henriksson, G (1); Reisch, L. (1); Srivastava, A (1); Bergman, O (1); Sonkoly, Enikö (1); Alström, P. (1); Tapia-Paez, I (1); Nordenskjöld, M (1); Sjöblom, Yvonne (1); Anil, Anandashankar (1); Sjöholm, A. (1); Asad, S (1); Taylan, F (1); Höjer, Pontus (1); Forsberg, M (1); Bluhm, G (1); Jankowski, P (1); Hunhammar, Sven (1); Rignér, Johan (1); Gossen, M (1); Karlson-Stiber, C (1); Pivarcsi, Andor (1); Berglund, O (1); Ståhle, M (1); Franke, Lude (1); Bieser, Jan C. T. (1); Bilberg, Johan, 1646 ... (1); Höjer, Laurentz J. (1); Spalinskas, Rapolas, ... (1); Howlett, Robert J. (1); Hammarin, AL (1); GRANDIEN, M (1); Wahlgren, C-F (1); Diez, T. (1); Höjer, Mattias, 1966 ... (1); Eisfeldt, J (1); Sjöblom, E (1); show less...

University: Royal Institute of Technology (8); Karolinska Institutet (6); Uppsala University (3); University of Gothenburg (2); University of Gävle (1)

Language: English (15); Swedish (1); Latin (1)

Research subject (UKÄ/SCB): Engineering and Technology (4); Social Sciences (2); Natural sciences (1); Medical and Health Sciences (1); Humanities (1)

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