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1.	Brown, KK, et al. (author) Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates 2008 In: Free radical biology & medicine. - : Elsevier BV. - 0891-5849. ; 45:4, s. 494-502 Journal article (peer-reviewed)
2.	Cox, AG, et al. (author) The thioredoxin reductase inhibitor auranofin triggers apoptosis through a Bax/Bak-dependent process that involves peroxiredoxin 3 oxidation 2008 In: Biochemical pharmacology. - : Elsevier BV. - 1873-2968 .- 0006-2952. ; 76:9, s. 1097-1109 Journal article (peer-reviewed)
3.	Dagnell, M, et al. (author) Bicarbonate is required for hydrogen peroxide-dependent inactivation of PTP1B in presence of the Trx system and peroxiredoxin 2018 In: FREE RADICAL BIOLOGY AND MEDICINE. - : Elsevier BV. - 0891-5849. ; 120, s. S36-S36 Conference paper (other academic/artistic)
4.	Dagnell, M, et al. (author) Thioredoxin reductase 1 and NADPH directly protect protein tyrosine phosphatase 1B from inactivation during H2O2 exposure 2017 In: The Journal of biological chemistry. - 1083-351X. ; 292:35, s. 14371-14380 Journal article (peer-reviewed)
5.	Fadeel, B, et al. (author) Involvement of caspases in neutrophil apoptosis: regulation by reactive oxygen species 1998 In: Blood. - 0006-4971. ; 92:12, s. 4808-4818 Journal article (peer-reviewed)
6.	Hampton, MB, et al. (author) Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis 1997 In: FEBS letters. - 0014-5793. ; 414:3, s. 552-556 Journal article (peer-reviewed)
7.	Hampton, MB, et al. (author) Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts 1998 In: The Biochemical journal. - : Portland Press Ltd.. - 0264-6021 .- 1470-8728. ; 329329 ( Pt 1), s. 95-99 Journal article (peer-reviewed)abstract The export of cytochrome c from mitochondria to the cytoplasm has been detected during apoptosis. Addition of cytochrome c to cytosolic extracts can activate the caspases, suggesting that this export could be an important intracellular signal for initiating the apoptotic programme. We have investigated the mechanism of caspase activation by cytochrome c. Mitochondrial cytochrome c normally shuttles electrons between complexes III and IV of the electron transport chain. Interaction with these complexes is dependent on electrostatic interactions via a polylysine binding pocket. Cytosolic caspase activation was only observed with intact holocytochrome c, and increasing the ionic composition of the extracts prevented activation, suggesting that stringent allosteric interactions between cytochrome c and other cytoplasmic factors are necessary. Cytochrome c was fully reduced within 5 min of addition to the cytosolic extracts. Potassium ferricyanide could maintain cytochrome c in an oxidized state, but care was taken to use ferricyanide at concentrations where its polyanion effect did not cause interference. The oxidized form of cytochrome c was able to activate the caspases. We conclude that reduced cytochrome c will function in the cytoplasm; however, its reduction is not a critical step, and electron transfer from cytochrome c to its cytoplasmic-binding partner(s) is not necessary in the pathway leading to apoptosis.
8.	Hampton, MB, et al. (author) Involvement of extracellular calcium in phosphatidylserine exposure during apoptosis 1996 In: FEBS letters. - 0014-5793. ; 399:3, s. 277-282 Journal article (peer-reviewed)
9.	Hampton, MB, et al. (author) Redox regulation of apoptotic cell death 1998 In: BioFactors (Oxford, England). - : Wiley. - 0951-6433 .- 1872-8081. ; 8:1-2, s. 1-5 Journal article (peer-reviewed)
10.	Hampton, MB, et al. (author) Redox regulation of apoptotic cell death in the immune system 1998 In: Toxicology letters. - 0378-4274. ; 103102-103, s. 355-358 Journal article (peer-reviewed)

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Type of publication: journal article (14); conference paper (1)

Type of content: peer-reviewed (12); other academic/artistic (3)

Author/Editor: Davies, M. (2); Evans, H. (2); Jones, G. (2); King, M. (2); Lopes, L. (2); Losada, M. (2); show more...; Martin, B. (2); Negri, G. (2); Nordberg, M. (2); Qureshi, A. (2); Robson, A. (2); Romano, M. (2); Shaw, K. (2); Ventura, D. (2); Wall, R. (2); Williams, S. (2); Yang, H. (2); Morton, A. (2); Davies, E. (2); Liu, H. (2); Valente, P. (2); Liu, T. (2); Bertoli, G (2); Stewart, G. (2); Martin, J. (2); Alves, R. (2); Aytac, E (2); Campain, N (2); Davies, RJ (2); Hompes, R (2); Lakkis, Z (2); McGrath, JS (2); Maciel, J (2); Rausa, E (2); Rottoli, M (2); Shaikh, (2); Tsarkov, P (2); Brown, A. (2); James, A. (2); Zhang, Y. (2); Cardoso, J. (2); Sharma, S. (2); Silva, M. (2); Martin, S. (2); Diaz, S (2); Jones, M. (2); Manca, G. (2); Moore, R. (2); Russ, J. (2); Shaw, S. (2); show less...

University: Karolinska Institutet (16)

Language: English (17)

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