| 1. |
- Holm, Sten, 1948, et al.
(author)
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Reactive changes in the adolescent porcine spine with disc degeneration due to endplate injury
- 2007
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In: Vet Comp Orthop Traumatol. - 0932-0814. ; 20:1, s. 12-7
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Journal article (peer-reviewed)abstract
- Degenerative and reactive structural alterations occurring after experimentally-induced disc degeneration were evaluated using a porcine model. A cranial perforation was made through the L4 vertebral endplate into the nucleus pulposus. Three months later, the lumbar intervertebral disc and adjacent vertebrae were dissected, fixed in formalin and further processed for histopathological analyses. The results showed that there were nucleus pulposus fragments, rather than a distinct border between the nucleus and annulus fibrosus. The central lamellae were distorted and delamination of the outer anterior layers was observed. Blood vessels emerged from the adjacent tissue, penetrated the annulus and branched into the residues of the nucleus. Nerve fibres accompanying the blood vessels could be recognized in the disc within the connective scar tissue. The epiphyseal cartilage plates in the vertebrae were hypertrophic in several areas and there was bone formation directed towards the centre of the vertebral body and the disc. Hypertrophic hyaline cartilage, newly formed bone and scar tissue filled the injury canal. A slight chronic inflammatory reaction was evident along vascular buds. The reactive changes dominated over the degenerated features in the operated disc. Physiological loading enhanced the infiltration of various tissue types characterizing immature cartilage formation. Prominent neovascularisation of the central parts of the disc is likely to be of key importance in turning the degenerative features of the remaining tissue into reactive healthy structures.
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| 2. |
- Orru, Kati, et al.
(author)
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Approaches to 'vulnerability' in eight European disaster management systems
- 2022
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In: Disasters. The Journal of Disaster Studies, Policy and Management. - : Wiley. - 0361-3666 .- 1467-7717. ; 46:3, s. 742-767
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Journal article (peer-reviewed)abstract
- While social vulnerability in the face of disasters has received increasing academic attention, relatively little is known about the extent to which that knowledge is reflected in practice by institutions involved in disaster management. This study charts the practitioners’ approaches to disaster vulnerability in eight European countries: Belgium; Estonia; Finland; Germany; Hungary; Italy; Norway; and Sweden. It draws on a comparative document analysis and 95 interviews with disaster managers and reveals significant differences across countries in terms of the ontology of vulnerability, its sources, reduction strategies, and the allocation of related duties. To advance the debate and provide conceptual clarity, we put forward a heuristic model to facilitate different understandings of vulnerability along the dimensions of human agency and technological structures as well as social support through private relations and state actors. This could guide risk analysis of and planning for major hazards and could be adapted further to particular types of disasters.
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| 3. |
- TEDDY study group, The, et al.
(author)
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The environmental determinants of diabetes in the young (TEDDY) study: Study design
- 2007
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In: Pediatric Diabetes. - : Hindawi Limited. - 1399-543X .- 1399-5448. ; 8:5, s. 286-298
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Journal article (peer-reviewed)abstract
- The primary objective of this multicenter, multinational, epidemiological study is the identification of infectious agents, dietary factors, or other environmental exposures that are associated with increased risk of autoimmunity and type 1 diabetes mellitus (T1DM). Factors affecting specific phenotypic manifestations such as early age of onset or rate of progression or with protection from the development of T1DM will also be identified. The Environmental Determinants of Diabetes in the Young (TEDDY) is an observational cohort study in which newborns who are younger than 4 months and have high-risk human leukocyte antigen alleles in the general population or are first-degree relatives (FDRs) of patients affected with T1DM will be enrolled. Six clinical centers in the USA and Europe will screen 361 588 newborns, of which it is anticipated that 17 804 will be eligible for enrollment with just over 7800 followed. Recruitment will occur over 5 yr, with children being followed to the age of 15 yr. Identification of such factors will lead to a better understanding of disease pathogenesis and result in new strategies to prevent, delay, or reverse T1DM.
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| 4. |
- Torpan, Sten, et al.
(author)
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European emergency managers on social media : institutional arrangements and guidelines
- 2023
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In: International Journal of Emergency Services. - 2047-0894 .- 2047-0908.
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Journal article (peer-reviewed)abstract
- Purpose - This paper offers an empirical overview of European emergency managers' institutional arrangements and guidelines for using social media in risk and crisis communication.Design/methodology/approach - The authors collected and analysed material including publicly accessible relevant legal acts, policy documents, official guidelines, and press reports in eight European countries – Germany, Italy, Belgium, Sweden, Hungary, Finland, Norway, and Estonia. Additionally, the authors carried out 95 interviews with emergency managers in the eight countries between September 2019 and February 2020.Findings - The authors found that emergency management institutions' social media usage is rarely centrally controlled and social media crisis communication was regulated with the same guidelines as crisis communication on traditional media. Considering this study's findings against the backdrop of existing research and practice, the authors find support for a “mixed arrangement” model by which centralised policies work in tandem with decentralised practices on an ad hoc basis.Practical implications - Comparative insights about institutional arrangements and procedural guidelines on social media crisis communication in the studied countries could inform the future policies concerning social media use in other emergency management systems.Originality/value - This study includes novel, cross-national comparative data on the institutional arrangements and guidelines for using social media in emergency management in the context of Europe.
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| 5. |
- Torpan, Sten, et al.
(author)
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Handling false information in emergency management : A cross-national comparative study of European practices
- 2021
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In: International Journal of Disaster Risk Reduction. - : Elsevier BV. - 2212-4209. ; 57
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Journal article (peer-reviewed)abstract
- During emergencies, exposure to false information can increase individual vulnerability. More research is needed on how emergency management institutions understand the effects of false information and what are the various approaches to handling it. Our document analysis and 95 expert interviews in eight European countries ? Germany, Italy, Belgium, Sweden, Hungary, Norway, Finland, and Estonia ? show that approaches vary considerably: some have instituted central management of identifying and tackling false information while others prioritise the spreading of accurate information. A review of national practices and an analysis of recent crisis cases show that both approaches may be necessary. The diffusion of false information is strongly affected by the lack of timely and verifiable information from governments. We also find that in several countries, the emergence of false information is often associated with malicious foreign influence activities. Our study contributes to a better understanding of how the effects of false information are mitigated by the emergency management systems in Europe.
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| 6. |
- Torpan, Sten, et al.
(author)
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Mitigating vulnerabilities with social media : A cross-national study of European disaster managers' practices
- 2024
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In: Risk, Hazards & Crisis in Public Policy. - 1944-4079.
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Journal article (peer-reviewed)abstract
- In this article, we provide an overview of the ways in which disaster managers in eight European countries use social media to mitigate people's vulnerability to hazards. Our document analysis and 95 expert interviews in Germany, Italy, Belgium, Sweden, Hungary, Finland, Norway, and Estonia revealed six distinct institutional social media practices that may reduce disaster vulnerability: sharing educational guidelines, informing and warning the public, identifying citizens' concerns, identifying missing persons, sharing guidelines during disaster, and organizing volunteers. We discuss how these practices could affect people's ability to access, understand, and react adequately to information about risks and hazards. Our findings can be used to improve guidelines for official crisis communication on social media and demonstrate the value of using social media in disaster risk reduction.
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| 7. |
- Aad, G., et al.
(author)
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Commissioning of the ATLAS Muon Spectrometer with cosmic rays
- 2010
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In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 70:3, s. 875-916
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Journal article (peer-reviewed)abstract
- The ATLAS detector at the Large Hadron Collider has collected several hundred million cosmic ray events during 2008 and 2009. These data were used to commission the Muon Spectrometer and to study the performance of the trigger and tracking chambers, their alignment, the detector control system, the data acquisition and the analysis programs. We present the performance in the relevant parameters that determine the quality of the muon measurement. We discuss the single element efficiency, resolution and noise rates, the calibration method of the detector response and of the alignment system, the track reconstruction efficiency and the momentum measurement. The results show that the detector is close to the design performance and that the Muon Spectrometer is ready to detect muons produced in high energy proton-proton collisions.
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