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1.	Chen, QJ, et al. (author) The semiconserved head structure of Plasmodium falciparum erythrocyte membrane protein 1 mediates binding to multiple independent host receptors 2000 In: The Journal of experimental medicine. - : Rockefeller University Press. - 0022-1007 .- 1540-9538. ; 192:1, s. 1-9 Journal article (peer-reviewed)abstract Erythrocytes infected with mature forms of Plasmodium falciparum do not circulate but are withdrawn from the peripheral circulation; they are bound to the endothelial lining and to uninfected erythrocytes in the microvasculature. Blockage of the blood flow, hampered oxygen delivery, and severe malaria may follow if binding is excessive. The NH2-terminal head structure (Duffy binding–like domain 1 [DBL1α]–cysteine-rich interdomain region [CIDR1α]) of a single species of P. falciparum erythrocyte membrane protein 1 (PfEMP1) is here shown to mediate adherence to multiple host receptors including platelet-endothelial cell adhesion molecule 1 (PECAM-1)/CD31, the blood group A antigen, normal nonimmune immunoglobulin M, three virulence-associated receptor proteins, a heparan sulfate–like glucosaminoglycan, and CD36. DBL2δ was found to mediate additional binding to PECAM-1/CD31. The exceptional binding activity of the PfEMP1 head structure and its relatively conserved nature argues that it holds an important role in erythrocyte sequestration and therefore in the virulence of the malaria parasite.
2.	Heddini, A, et al. (author) Fresh isolates from children with severe Plasmodium falciparum malaria bind to multiple receptors 2001 In: Infection and immunity. - 0019-9567. ; 69:9, s. 5849-5856 Journal article (peer-reviewed)
3.	Brodin, J, et al. (author) Challenges with using primer IDs to improve accuracy of next generation sequencing 2015 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 10:3, s. e0119123- Journal article (peer-reviewed)
4.	Heddini, A, et al. (author) Binding of Plasmodium falciparum-infected erythrocytes to soluble platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): frequent recognition by clinical isolates 2001 In: The American journal of tropical medicine and hygiene. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 65:1, s. 47-51 Journal article (peer-reviewed)
5.	Heddini, A, et al. (author) Enrichment of immunoglobulin binding Plasmodium falciparum-infected erythrocytes using anti-immunoglobulin-coated magnetic beads 1998 In: The American journal of tropical medicine and hygiene. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 59:5, s. 663-666 Journal article (peer-reviewed)
6.	Heddini, A (author) Malaria pathogenesis: a jigsaw with an increasing number of pieces 2002 In: International journal for parasitology. - 0020-7519. ; 32:13, s. 1587-1598 Journal article (peer-reviewed)
7.	Heddini, A, et al. (author) The multilateral initiative on malaria: past, present, and future 2004 In: The American journal of tropical medicine and hygiene. - : American Society of Tropical Medicine and Hygiene. - 0002-9637 .- 1476-1645. ; 71:22 Suppl, s. 279-282 Journal article (peer-reviewed)
8.	Hedskog, C, et al. (author) Longitudinal ultradeep characterization of HIV type 1 R5 and X4 subpopulations in patients followed from primary infection to coreceptor switch 2013 In: AIDS research and human retroviruses. - : Mary Ann Liebert Inc. - 1931-8405 .- 0889-2229. ; 29:9, s. 1237-1244 Journal article (peer-reviewed)
9.	Sankoh, Osman, et al. (author) Sharing the research data to improve public health : a perspective from the global south 2011 In: The Lancet. - 0140-6736 .- 1474-547X. ; 378:9789, s. 401-402 Journal article (peer-reviewed)
10.	Treutiger, CJ, et al. (author) PECAM-1/CD31, an endothelial receptor for binding Plasmodium falciparum-infected erythrocytes 1997 In: Nature medicine. - : Springer Science and Business Media LLC. - 1078-8956 .- 1546-170X. ; 3:12, s. 1405-1408 Journal article (peer-reviewed)

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Type of publication: journal article (10)

Type of content: peer-reviewed (10)

Author/Editor: Heddini, A (9); Wahlgren, M (5); Fernandez, V (3); Chen, QJ (3); Albert, J. (2); Marsh, K (2); show more...; Treutiger, CJ (2); Kai, O (2); Mild, M (2); Barragan, A (2); Brodin, J (2); Hedskog, C (2); Obiero, J (2); Muller, WA (2); Owusu-Agyei, Seth (1); Byass, Peter (1); Juvekar, Sanjay (1); Sankoh, Osman (1); Pettersson, F (1); Bratt, G (1); French, Neil (1); Heddini, Andreas (1); Tollman, Stephen (1); Fonn, Sharon (1); Herbst, Kobus (1); Molla, Mitike (1); Bonita, Ruth (1); Benard, E (1); Neher, RA (1); de Savigny, Don (1); Lutalo, Tom (1); Zaba, Basia (1); Pearce, SFA (1); Cravioto, Alejandro (1); Mbacke, Cheikh (1); Ross, David A. (1); Shafi, J (1); Keusch, GT (1); Davies, CS (1); Ezeh, Alex (1); Newell, Marie-Louise (1); Madise, Nyovani (1); Ijsselmuiden, Carel (1); Kouanda, Seni (1); Marais, Debbie (1); Clark, Sam (1); Ye, Yazoume (1); van Ginneken, Jeroen (1); Laserson, Kayla (1); show less...

University: Karolinska Institutet (9); Umeå University (1)

Language: English (10)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

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