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1.	Zaigham, Mehreen, et al. (author) Prelabour caesarean section and neurodevelopmental outcome at 4 and 12 months of age : an observational study 2020 In: BMC Pregnancy and Childbirth. - : BMC. - 1471-2393 .- 1471-2393. ; 20 Journal article (peer-reviewed)abstract Background: With prelabour caesarean section rates growing globally, there is direct and indirect evidence of negative cognitive outcomes in childhood. The objective of this study was to assess the short-term neurodevelopmental outcomes after prelabour caesarean section as compared to vaginally born infants.Methods: We conducted a prospective, observational study of infants delivered by prelabour caesarean section at the Hospital of Halland, Halmstad, Sweden and compared their development with an historical group of infants born by non-instrumental vaginal delivery.Results: Infants born by prelabour caesarean section were compared with a group of vaginally born infants. Follow-up assessments were performed at 4 and 12 months. Prelabour caesarean infants (n = 66) had significantly lower Ages and Stages Questionnaire, second edition (ASQ-II) scores in all domains (communication, gross motor, fine motor, problem solving and personal-social) at 4 months of age with an adjusted mean difference (95% CI) of - 20.7 (- 28.7 to - 12.6) in ASQ-II total score as compared to vaginally born infants (n = 352). These differences remained for gross-motor skills at the 12 month assessment, adjusted mean difference (95% CI) -4.7 (- 8.8 to - 0.7),n = 62 and 336.Conclusions: Adverse neurodevelopmental outcomes in infants born by prelabour caesarean section may be apparent already a few months after birth. Additional studies are warranted to explore this relationship further.

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Type of publication: journal article (56); conference paper (7); research review (6)

Type of content: peer-reviewed (55); other academic/artistic (14)

Author/Editor: Bachert, C (59); Mullol, J (49); Hellings, PW (35); Bousquet, J (33); Klimek, L (26); Ryan, D. (26); show more...; Sheikh, A (25); Demoly, P. (25); Zuberbier, T (25); Bedbrook, A (25); Kuna, P (25); Samolinski, B (25); Valiulis, A. (25); Haahtela, T (24); Yorgancioglu, A (23); Kvedariene, V (23); Valovirta, E. (23); Agache, I (22); Passalacqua, G (22); Muraro, A (21); Morais-Almeida, M. (21); Price, D. (20); Pfaar, O (20); Fokkens, WJ (20); Devillier, P. (20); Melen, E (19); Hellings, P (19); Kull, I (18); Cardona, V (18); Wickman, M (17); Canonica, GW (17); Annesi-Maesano, I (17); Larenas-Linnemann, D (17); Todo-Bom, A. (17); Keil, T (16); Bindslev-Jensen, C (16); Just, J (16); Toppila-Salmi, S. (16); Schmid-Grendelmeier, ... (15); Murray, R. (15); Menditto, E. (15); Zhang, L. (14); Gevaert, P (14); Palkonen, S (14); Pawankar, R (14); Arnavielhe, S (14); Papadopoulos, NG (14); Illario, M. (14); Bosse, I. (14); Emuzyte, R. (14); show less...

University: Karolinska Institutet (66); Lund University (10); Uppsala University (8); Linköping University (6); Umeå University (4)

Language: English (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (1)

Year: 2020 (1)

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