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1.	Nilsson, Magnus, et al. (author) Neoadjuvant Chemoradiotherapy and Surgery for Esophageal Squamous Cell Carcinoma Versus Definitive Chemoradiotherapy With Salvage Surgery as Needed : The Study Protocol for the Randomized Controlled NEEDS Trial 2022 In: Frontiers in Oncology. - : Frontiers Media S.A.. - 2234-943X. ; 12 Journal article (peer-reviewed)abstract Background: The globally dominant treatment with curative intent for locally advanced esophageal squamous cell carcinoma (ESCC) is neoadjuvant chemoradiotherapy (nCRT) with subsequent esophagectomy. This multimodal treatment leads to around 60% overall 5-year survival, yet with impaired post-surgical quality of life. Observational studies indicate that curatively intended chemoradiotherapy, so-called definitive chemoradiotherapy (dCRT) followed by surveillance of the primary tumor site and regional lymph node stations and surgery only when needed to ensure local tumor control, may lead to similar survival as nCRT with surgery, but with considerably less impairment of quality of life. This trial aims to demonstrate that dCRT, with selectively performed salvage esophagectomy only when needed to achieve locoregional tumor control, is non-inferior regarding overall survival, and superior regarding health-related quality of life (HRQOL), compared to nCRT followed by mandatory surgery, in patients with operable, locally advanced ESCC.Methods: This is a pragmatic open-label, randomized controlled phase III, multicenter trial with non-inferiority design with regard to the primary endpoint overall survival and a superiority hypothesis for the experimental intervention dCRT with regard to the main secondary endpoint global HRQOL one year after randomization. The control intervention is nCRT followed by preplanned surgery and the experimental intervention is dCRT followed by surveillance and salvage esophagectomy only when needed to secure local tumor control. A target sample size of 1200 randomized patients is planned in order to reach 462 events (deaths) during follow-up.
2.	Woll, Petter S, et al. (author) Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo. 2014 In: Cancer Cell. - : Elsevier BV. - 1878-3686 .- 1535-6108. ; 25:6, s. 794-808 Journal article (peer-reviewed)abstract Evidence for distinct human cancer stem cells (CSCs) remains contentious and the degree to which different cancer cells contribute to propagating malignancies in patients remains unexplored. In low- to intermediate-risk myelodysplastic syndromes (MDS), we establish the existence of rare multipotent MDS stem cells (MDS-SCs), and their hierarchical relationship to lineage-restricted MDS progenitors. All identified somatically acquired genetic lesions were backtracked to distinct MDS-SCs, establishing their distinct MDS-propagating function in vivo. In isolated del(5q)-MDS, acquisition of del(5q) preceded diverse recurrent driver mutations. Sequential analysis in del(5q)-MDS revealed genetic evolution in MDS-SCs and MDS-progenitors prior to leukemic transformation. These findings provide definitive evidence for rare human MDS-SCs in vivo, with extensive implications for the targeting of the cells required and sufficient for MDS-propagation.
3.	Aapro, Matti S., et al. (author) Erythropoietins should be used according to guidelines 2008 In: The Lancet Oncology. - 1470-2045 .- 1474-5488. ; 9:5, s. 412-3 Journal article (peer-reviewed)
4.	Decker, Ralph, 1968, et al. (author) Long-term Effects of Growth Hormone in Children 2014 In: Update on GH and IGFs, 22-23 maj 2014, Stockholm, Sverige. Nobelforum Karolinska institutet - Svenska Endokrinolog Föreningen. Conference paper (other academic/artistic)
5.	Hellström, John S. (author) Den kommersiella idrottens utveckling speglat i sex amerikanska rättsfall om yttrandefrihet vs. förtal : recension av boken Game Faces: Sport celebrity and the laws of reputation av Sarah K. Fields 2017 In: Idrottsforum.org/Nordic sport science forum. - 1652-7224. Review (other academic/artistic)
6.	Hellström, John S. (author) Elitidrottares motivbild skärskådas med nykommen metod : recension av boken Life Story Research in Sport: Understanding the experiences of elite and professional athletes through narrative / Kitrina Douglas & David Carless 2016 In: Idrottsforum.org/Nordic sport science forum. - 1652-7224. Review (other academic/artistic)
7.	Hellström, John S., et al. (author) Historisk forskning 2014 In: Från Kungl. Gymnastiska Centralinstitutet till Gymnastik- och idrottshögskolan. - Stockholm : Gymnastik- och idrottshögskolan, GIH. ; , s. 207-209 Book chapter (pop. science, debate, etc.)
8.	Hellström, John S. (author) Idrottshjältar i media 2020 In: Sport management. Del 3. - Stockholm : SISU idrottsböcker. - 9789177270782 ; , s. 112-131 Book chapter (other academic/artistic)
9.	Hellström, John S. (author) Life stories of seemingly uninteresting athletes offer a deeper understanding of the conditions that formed modern sport in Britain and Europe : book review of Sporting Lives / Dave Day ed., 2011 2021 In: Idrottsforum.org/Nordic sport science forum. - : Malmö University. - 1652-7224. ; :April 21 Review (other academic/artistic)abstract Dave Day’s edited collection from 2011, Sporting Lives (MMU Institute for Performance Research) originates from a Sporting Lives symposium hosted by MMU Cheshire, and must be considered a modern sport history classic. John S. Hellström is our reviewer, and he finds the sum of the parts to be most rewarding, even though some individual contributions are highly readable. Shame, though, that only one of eleven chapters is written about a women.
10.	Hellström, John S., et al. (author) Manliness and modernity : the media construction of boxer Ingemar Johansson as a national sport hero 2020 In: European Studies in Sports History. - : European Committee for Sports History (CESH). - 1999-8589. ; 12 Journal article (peer-reviewed)

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Type of publication: journal article (5); book chapter (3); review (3); conference paper (2)

Type of content: peer-reviewed (7); other academic/artistic (5); pop. science, debate, etc. (1)

Author/Editor: Hellström-Lindberg, ... (2); Yttergren, Leif (1); Aapro, Matti S. (1); Birgegård, Gunnar, 1 ... (1); Bokemeyer, Carsten (1); Cornes, Paul (1); show more...; Foubert, Jan (1); Gascon, Pere (1); Glaspy, John (1); Link, Hartmut (1); Ludwig, Heinz (1); Österborg, Anders (1); Repetto, Lazzaro (1); Soubeyran, Pierre (1); Nilsson, Magnus (1); Josefsen, Dag (1); Kvalheim, Gunnar (1); Nilsson, Lars (1); Johansson, Jan (1); Hellström, Ann, 1959 (1); Bang, Peter (1); Anderson, Kristina (1); Jacobsen, Sten Eirik ... (1); Johannsson, Gudmundu ... (1); Deng, Qiaolin (1); Johansson, Hemming (1); Taylor, Stephen (1); Olsson, Daniel S, 19 ... (1); Edholm, David (1); Sävendahl, Lars (1); Dahlgren, Jovanna, 1 ... (1); Alexandersson von Dö ... (1); Wedge, David C. (1); Papaemmanuil, Elli (1); Campbell, Peter J. (1); Sandberg, Rickard (1); Lagergren, Pernilla (1); Unnikrishnan, Ashwin (1); Pimanda, John E. (1); Nerlov, Claus (1); Decker, Ralph, 1968 (1); Yttergren, Leif, 195 ... (1); Wallner, Bengt, 1962 ... (1); Hedberg, Jakob, 1972 ... (1); Rosén, Thord, 1949 (1); Nilsson, Anna G, 196 ... (1); Hellström, Mats (1); Ngara, Mtakai (1); Piessen, Guillaume (1); Reynolds, John V. (1); show less...

University: The Swedish School of Sport and Health Sciences (9); Karolinska Institutet (3); Uppsala University (2); University of Gothenburg (1); Umeå University (1); Linköping University (1); show more...; Lund University (1); show less...

Language: English (7); Swedish (6)

Research subject (UKÄ/SCB): Humanities (7); Medical and Health Sciences (6)

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