| 1. |
- Barreto Henriksson, Helena, et al.
(author)
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Determination of mechanical and rheological properties of a cell-loaded peptide gel during ECM production
- 2019
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In: International Journal of Pharmaceutics. - : Elsevier BV. - 0378-5173 .- 1873-3476. ; 563, s. 437-444
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Journal article (peer-reviewed)abstract
- The development of an injectable biomaterial that supports cell survival and maintains or promotes nucleus pulposus (NP) phenotype could aid delivery of cells to degenerated NPs causing low back pain. Mesenchymal cells were loaded and grown in a synthetic peptide gel, PuraMatrix (R). Cells were observed within the gels over 0-28 days, and accumulation of glycosaminoglycans were detected by histological staining. The mechanical properties of the cell-loaded constructs, and the change of the mechanical properties were studied using stress relaxation of the gels under compression and confinement. The PuraMatrix (R) gel was shown to relax fast on compression indicating that the fluid could easily flow out of the gel, and thus indicating the presence of large pores/voids. The presence of these pores/voids was further supported by high mobility of dextran molecules, determined using fluorescence recovery after photo bleaching. The stress required to deform the cell-loaded constructs to a specific strain increases at day 21, at which point the presence of glycosaminoglycans within the cell-loaded constructs was also observed. The results provide evidence of changes in mechanical properties of the PuraMatrix (R) matrix upon excretion of the extracellular matrix by the cells.
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| 2. |
- Bing, Vibeke, et al.
(author)
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Det har både blivit lättare och svårare - om det nya i att arbeta på familjecentraler
- 2011
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In: Socialmedicinsk Tidskrift. - 0037-833X. ; 88:2, s. 133-143
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Journal article (other academic/artistic)abstract
- Den här artikeln utgår ifrån personalens perspektiv. Första delen är resultat från en enkätstudie som fokuserar på hur personal förändrat sitt sätt att arbeta sedan de började arbeta på familjecentral. De flesta upplever att eftersom de har andra professioner i samma hus lättare upptäcker familjer med extra behov av stöd och bättre kan fokusera på sina egna arbetsuppgifter. Som fördjupning av svaren i enkäten har olika personalkategorier ombetts skriva en kortfattad berättelse om sitt eget arbete på familjecentral. Sjuksköterskor, barnmorska, psykolog, socionom, förskollärare, bibliotekarie och samordnare berättar hur de arbetar. Slutsatserna från artikeln är att familjecentraler kan ses som ett svar på att stödet till blivande och småbarnsföräldrar har utökats på de områden som den traditionella mödra- och barnhälsovården har sett som problematisk att möta. Sannolikt ökar förutsättningarna för att de som behöver extra stöd också kan få möjlighet till detta under förutsättning att extra stöd finns när familjecentralens resurser inte räcker till.
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| 3. |
- Bing, Vibeke, et al.
(author)
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Det har både blivit lättare och svårare - om det nya i att arbeta på familjecentraler
- 2011
-
In: Socialmedicinsk Tidskrift. - 0037-833X. ; 88:2, s. 133-143
-
Journal article (other academic/artistic)abstract
- Den här artikeln utgår ifrån personalens perspektiv. Första delen är resultat från en enkätstudie som fokuserar på hur personal förändrat sitt sätt att arbeta sedan de började arbeta på familjecentral. De flesta upplever att eftersom de har andra professioner i samma hus lättare upptäcker familjer med extra behov av stöd och bättre kan fokusera på sina egna arbetsuppgifter. Som fördjupning av svaren i enkäten har olika personalkategorier ombetts skriva en kortfattad berättelse om sitt eget arbete på familjecentral. Sjuksköterskor, barnmorska, psykolog, socionom, förskollärare, bibliotekarie och samordnare berättar hur de arbetar. Slutsatserna från artikeln är att familjecentraler kan ses som ett svar på att stödet till blivande och småbarnsföräldrar har utökats på de områden som den traditionella mödra- och barnhälsovården har sett som problematisk att möta. Sannolikt ökar förutsättningarna för att de som behöver extra stöd också kan få möjlighet till detta under förutsättning att extra stöd finns när familjecentralens resurser inte räcker till.
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| 4. |
- Henriksson, Anette, et al.
(author)
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A support group programme for relatives during the late palliative phase
- 2007
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In: International Journal of Palliative Nursing. - : Mark Allen Group. - 1357-6321 .- 2052-286X. ; 13:4, s. 175-183
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Journal article (peer-reviewed)abstract
- This study describes an intervention where relatives were invited to take part in a support group programme during the late palliative phase of their family member. The purpose was to describe their experiences of the support group programme and the subsequent impact on their lives as relatives of a terminally ill person. Qualitative interviews were chosen as the data collection method. The analysis was inspired by the phenomenological method as described by Giorgi (1989). The relatives’ experiences were categorised into six key constituents: confirmation; insight into the gravity of the illness; sense of belonging created by similar experiences; participation in the care system; being able to rest; and strength to provide support for the patient. These six constituents resulted in a sense of safety in relation to the patient, the illness, the nursing staff and the care unit. The study’s findings show that interventions of this kind may be integral to the relatives’ ability to handle their situation when caring for a terminally ill family member.
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| 5. |
- Henriksson, Anette, 1967-, et al.
(author)
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Adaptation and psychometric evaluation of the Preparedness for Caregiving Scale, Caregiver Competence Scale and Rewards of Caregiving Scale in a sample of Swedish family members of patients with life-threatening illness
- 2012
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In: Palliative Medicine. - London, United Kingdom : SAGE Publications. - 0269-2163 .- 1477-030X. ; 26:7, s. 930-938
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Journal article (peer-reviewed)abstract
- Background: Family members often take on many caring responsibilities, with complex issues and challenges to consider. Feelings of preparedness, competence and reward are identified as concepts that may protect caregiver wellbeing and decrease negative outcomes related to caregiving. Aim: This study aimed to translate, adapt and psychometrically evaluate the Preparedness for Caregiving Scale, Caregiver Competence Scale and Rewards of Caregiving Scale in Swedish family members of patients with life threatening illness. Design: Correlational. Setting/participants: The study took place in four settings including advanced palliative care. The scales were tested in a sample of 125 family members of persons with life-threatening illness. All three scales were tested in relation to distribution of item and scale scores, missing data patterns, dimensionality, convergent validity and reliability. Results: The results in this study indicate that the Swedish versions of The Preparedness for Caregiving Scale, Caregiver Competence Scale and Rewards of Caregiving Scale are valid, reliable and user-friendly scales. Confirmatory factor analysis showed that the scales were unidimensional and all demonstrated Cronbach's alpha values of ≥0.9. Conclusions: As a result of this study it is anticipated that the Preparedness for Caregiving Scale, Caregiver Competence Scale and Rewards of Caregiving Scale could provide a basis for collaborative research between different countries and make international studies more comparable and generalizable despite differences in language and culture. © 2011 The Author(s).
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| 6. |
- Henriksson, Anette, et al.
(author)
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Effects of a support group programme for family members of patients with life-threatening illness during ongoing palliative care
- 2012
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Other publication (other academic/artistic)abstract
- Background: Health care systems in many countries are moving towards outpatient care in which family members are central in providing care for patients with life-threatening illness. Several studies show that family members report lack of preparation, knowledge and ability to handle the caregiver role with a need for information and psychosocial support. Aim: The aim was to investigate effects of a support group programme for family members of patients with life-threatening illness during ongoing palliative care Design: A prospective quasi-experimental design including an intervention group and a comparison group was used. Settings/participants: A support group programme was offered to family members of patients with life-threatening illness during ongoing palliative care at three intervention settings, two specialist palliative care units and one haematology unit. A fourth setting, a specialist palliative care unit was used for comparisons. Results: Family members taking part in the support group programme significantly increased their perceptions of preparedness for caregiving, competence for caregiving and rewards of caregiving. No significant changes were shown for hope, anxiety, depression symptoms or health. Conclusions: The intervention, including a support group program delivered for family members of persons with life threatening illness during ongoing palliative care proved to be effective in certain domains of caregiving. No negative outcomes were detected. The results indicate that this intervention could be implemented and delivered to family members during ongoing palliative care.
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| 7. |
- Henriksson, Anette, 1967-, et al.
(author)
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Effects of a support group programme for patients with life-threatening illness during ongoing palliative care
- 2013
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In: Palliative Medicine. - London, United Kingdom : SAGE Publications (UK and US). - 0269-2163 .- 1477-030X. ; 27:3, s. 257-264
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Journal article (peer-reviewed)abstract
- Background: Health care systems in many countries are moving towards outpatient care in which family members are central in providing care for patients with life-threatening illness. Several studies show that family members report a lack of preparation, knowledge and the ability to handle the caregiver role, and a need for information and psychosocial support. less thanbrgreater than less thanbrgreater thanAim: The aim was to investigate the effects of a support group programme for family members of patients with life-threatening illness during ongoing palliative care. less thanbrgreater than less thanbrgreater thanDesign: A prospective quasi-experimental design, including an intervention group and a comparison group, was used. less thanbrgreater than less thanbrgreater thanSettings/participants: A support group programme was offered to family members during ongoing palliative care at three intervention settings: two specialist palliative care units and one haematology unit. A fourth setting, a specialist palliative care unit, was used for comparisons. less thanbrgreater than less thanbrgreater thanResults: Family members taking part in the support group programme significantly increased their perceptions of preparedness for caregiving, competence for caregiving, and rewards of caregiving. Hope, anxiety, depression symptoms and health showed no significant changes. less thanbrgreater than less thanbrgreater thanConclusions: The intervention, including a support group programme delivered to family members of patients with life-threatening illness during ongoing palliative care, proved to be effective in certain domains of caregiving. No negative outcomes were detected. The results indicate that this intervention could be implemented and delivered to family members during ongoing palliative care.
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| 8. |
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| 9. |
- Henriksson, Anette, et al.
(author)
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Meeting needs of family members of persons with life-threatening illness : a support group program during ongoing palliative care
- 2011
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In: Palliative & Supportive Care. - : Cambridge University Press. - 1478-9515 .- 1478-9523. ; 9:3, s. 263-271
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Journal article (peer-reviewed)abstract
- Objective: The aim of the study was to describe family members’ experiences of content, structure, and approach of a potential intervention including a support group program for family members of persons with life-threatening illness.Method: The study was a pilot project in a developmental phase in which a potential intervention, a support group program, was investigated. The design of the study was qualitative descriptive. Twenty-nine family members were interviewed by telephone after taking part in the program. The interviews were analyzed using qualitative content analysis.Results: The results indicate that the support group program could work as an acceptable and useful intervention for family members. The program was experienced to cover topics of immediate interest reflecting life close to severely ill persons. The structure of the program was found to be inviting, offering an opportunity to establish relationships with other participants and the caring team in a warm atmosphere.Significance of results: The study indicates the importance of health professionals inviting and interacting with family members during ongoing palliative care. The results could inspire nursing staff to initiate, develop, and deliver similar interventions.
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| 10. |
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