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- Biber, H., et al.
(författare)
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Sputtering Behavior of Rough, Polycrystalline Mercury Analogs
- 2022
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Ingår i: The Planetary Science Journal. - : Institute of Physics (IOP). - 2632-3338. ; 3:12
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Tidskriftsartikel (refereegranskat)abstract
- The solar wind continuously impacts on rocky bodies in space, eroding their surface, thereby contributing significantly to the exosphere formations. The BepiColombo mission to Mercury will investigate the Hermean exosphere, which makes an understanding of the precise formation processes crucial for evaluation of the acquired data. We therefore developed an experimental setup with two microbalances that allows us to compare the sputter behavior of deposited thin solid layers with that of real mineral samples in the form of pressed powder. In addition, this technique is used to study the angular distribution of the sputtered particles. Using 4 keV He+ and 2 keV Ar+ ions, the sputter behavior of pellets of the minerals enstatite (MgSiO3) and wollastonite (CaSiO3) is studied, because these minerals represent analogs for the surface of the planet Mercury or the Moon. Pellets of powdered enstatite show significantly lower sputter yields than thin amorphous enstatite films prepared by pulsed laser deposition. 3D simulations of sputtering based on surface topography data from atomic force microscopy show that the observed reduction can be explained by the much rougher pellet surface alone. We therefore conclude that sputter yields from amorphous thin films can be applied to surfaces of celestial bodies exposed to ion irradiation, provided the effects of surface roughness, as encountered in realistic materials in space, are adequately accounted for. This also implies that taking surface roughness into account is important for modeling of the interaction of the solar wind with the surface of Mercury.
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- Rowbotham, S. E., et al.
(författare)
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Inositol in the MAnaGemENt of abdominal aortic aneurysm (IMAGEN) : Study protocol for a randomised controlled trial
- 2017
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Ingår i: Trials. - : BioMed Central Ltd.. - 1745-6215. ; 18:1
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Tidskriftsartikel (refereegranskat)abstract
- Background: An abdominal aortic aneurysm (AAA) is a focal dilation of the abdominal aorta and is associated with a risk of fatal rupture. Experimental studies suggest that myo-inositol may exert beneficial effects on AAAs through favourable changes to biological pathways implicated in AAA pathology. The aim of the Inositol in the MAnaGemENt of abdominal aortic aneurysm (IMAGEN) trial is to assess if myo-inositol will reduce AAA growth. Methods/design: IMAGEN is a multi-centre, prospective, parallel-group, randomised, double-blind, placebo-controlled trial. A total of 164 participants with an AAA measuring ≥ 30 mm will be randomised to either 2 g of myo-inositol or identical placebo twice daily for 12 months. The primary outcome measure will be AAA growth estimated by increase in total infrarenal aortic volume measured on computed tomographic scans. Secondary outcome measures will include AAA diameter assessed by computed tomography and ultrasound, AAA peak wall stress and peak wall rupture index, serum lipids, circulating AAA biomarkers, circulating RNAs and health-related quality of life. All analysis will be based on the intention-to-treat principle at the time of randomisation. All patients who meet the eligibility criteria, provide written informed consent and are enrolled in the study will be included in the primary analysis, regardless of adherence to dietary allocation. Discussion: Currently, there is no known medical therapy to limit AAA progression. The IMAGEN trial will be the first randomised trial, to our knowledge, to assess the value of myo-inositol in limiting AAA growth.
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