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- Jamil, Wasim, et al.
(författare)
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Incidence Rate of Hand Eczema in Different Occupations : A Systematic Review and Meta-analysis
- 2022
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Ingår i: Acta Dermato-Venereologica. - : Taylor & Francis. - 0001-5555 .- 1651-2057. ; 102
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Forskningsöversikt (refereegranskat)abstract
- Hand eczema is a chronic disease that results in economic and psychosocial burdens. The aim of this study was to systematically review and assess the magnitude of the association between exposure related to occupations and the incidence rate of hand eczema. A systematic search in PubMed, EMBASE, CINAHL and Cochrane databases, from inception to September 2017, of full-text observational studies reporting incident cases of hand eczema during employment, and a supplementary search in PubMed to September 2020, were conducted. Among 2,417 screened abstracts, 15 studies fulfilled the inclusion criteria. Incidence rates were reported per 100 person-years. Based on the Newcastle-Ottawa Scale, 9 studies were good quality, 2 fair quality, and 4 poor quality. Hairdressers had a high incidence of hand eczema of 21.4 (95% confidence interval [CI] 15.3-27.4), as did nurses, 16.9 (95% CI 11.2-22.7), and metal workers, 12.4 (95% CI 3.5-21.3). Hairdressers were predominantly women, and metal worker were predominantly men. Office occupations had an incidence rate of hand eczema of 4.9 (95% CI 1.2-9.6). The high risk of hand eczema for hairdressers, nurses, and metal workers, should be considered by healthcare policymakers. Even occupations with low irritant profile, such as office workers, were at risk of developing hand eczema, and more occupations should be investigated regarding the related risk of developing hand eczema.
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- Jamil, Wasim N., 1985-
(författare)
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Aspects on the hand eczema and the current health care system : the possibility of health related quality of life measure as a tool for follow-up patients
- 2020
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- Contact eczema is the most common occupational skin disease, and it predominantly affects the hands. Hand eczema is a chronic and fluctuating disease with a multidimensional impact on the patient and society, resulting in an increased consumption of health care, long term sick leave, in voluntary change of occupation, and a risk of early retirement and impaired healthrelated quality of life.A meta-analysis was conducted to determine the magnitude of the association between occupations and the risk of hand eczema. An increased risk of hand eczema was quantified among hairdressers, as well as nurses, metal workers and office workers (paper I).Currently, patients with chronic hand eczema are referred to a dermatology clinic for further treatment and investigation. Patch testing is a well established procedure for confirming or excluding the role of causative allergen that comes in contact with the hands. After patch testing, a majority of patients are referred back to primary health care without follow-up. In a questionnaire study, 1-10 years after patch testing, we found that many patients forgot their patch test results, and still reported concerns with aspects of their work (papers II-III). In addition, there was no association between patch test results and reporting a better health-related quality of life (paper III). For hand eczema and/or atopic dermatitis patients, we evaluated the change of health-related quality of life (HRQoL) at every three months, and the need for health care. An impairment in health-related quality of life, corresponding to a significant clinical value, can predict the worsening of eczema and the need of health care to re-evaluate its treatment (paper IV).Our study suggests the importance of the adoption of long-term management for hand eczema patients, and regularly using HRQoL measure,as the dermatology life quality index, to discover which patients require further adjustment of treatment.
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- Jamil, Wasim N., 1985-, et al.
(författare)
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Effects of time and recall of patch test results on quality of life (QoL) after testing : Cross-sectional study analyzing QoL in hand eczema patients 1, 5 and 10 years after patch testing
- 2017
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Ingår i: Contact Dermatitis. - Hoboken, USA : Wiley-Blackwell. - 0105-1873 .- 1600-0536. ; 77:2, s. 88-94
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Tidskriftsartikel (refereegranskat)abstract
- Background: Patch testing can improve health-related quality of life (HRQoL).Objectives: To study the impact on HRQoL of elapsed time after patch testing (1-10 years), and how the outcome of testing and patients' recall affects HRQoL.Patients/materials/methods: The Dermatology Life Quality Index (DLQI) questionnaire was sent to all patients (aged 18-65 years) who were patch tested for suspected contact allergy in 2009, 2005 and 2000 at the Department of Dermatology in Örebro.Results: The response rate was 51% (n = 256). The DLQI score was significantly lower at 10 years after patch testing (mean DLQI = 5.5) than at 1 year (mean DLQI = 7.7). Work was the most impaired aspect. A binary logistic model showed that only time (10 years after testing) was associated with no effect, a light effect or a moderate effect (DLQI < 10) on HRQoL. No such association was seen for patients with negative or positive test results concerning full recall, partial recall or no recall of diagnosed allergens.Conclusions: Although there was an improvement in HRQoL over time, the work aspect remained a major problem. The improvement was not affected by the outcome of testing and patients' recall of test results.
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- Jamil, Wasim N., 1985-, et al.
(författare)
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How well is the outcome of patch testing remembered by the patients? : A 10-year follow-up of testing with the Swedish baseline series at the Department of Dermatology in Örebro, Sweden
- 2012
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Ingår i: Contact Dermatitis. - Malden, USA : Wiley-Blackwell. - 0105-1873 .- 1600-0536. ; 66:4, s. 215-220
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Tidskriftsartikel (refereegranskat)abstract
- Background: Patch testing is beneficial for patients with contact dermatitis. However, it is not known how well the outcome of patch testing is remembered after a prolonged period.Objectives: To study how well patients remember the outcome of their tests after 1-10 years. Patients/materials/methods. In 2010, a questionnaire was sent to all patients tested with the Swedish baseline series in 2009, 2005, and 2000.Results: The response rate was 53.3% (252/473), and 96% (241/252) of patients reported that they had been submitted for allergy testing. Among those with positive patch test results, 79% (111/141) remembered a positive result and 29% (41/141) reported the correct name of the allergen. We found a wide variation (0-80%) in how well the patients remembered positive test results for different allergens. The ability to recall allergens had no relationship with the localization or extension of eczema lesions, but was negatively correlated with the number of diagnosed allergies, the number of years after patch testing, and being male.Conclusions: Our results indicate that improved information for patients following patch testing is required, in order to improve the prognosis of contact dermatitis.
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- Pettersson-Pablo, Paul, 1986-, et al.
(författare)
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Reference interval for type III procollagen (PIIINP) using the Advia centaur PIIINP assay in adults and elderly
- 2021
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Ingår i: Scandinavian Journal of Clinical and Laboratory Investigation. - : Taylor & Francis. - 0036-5513 .- 1502-7686. ; 81:8, s. 649-652
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: The amino-terminal peptide of type III procollagen (PIIINP) is a byproduct of type III collagen synthesis that exhibits promise as a biomarker of fibrosis, specifically in monitoring hepatic fibrosis in methotrexate treated patients. The Advia Centaur® PIIINP assay is developed for track-based automated laboratory systems and is suitable for large volume analysis. Reference intervals in children and younger adults have been published previously. Here we measured PIIINP to determine reference ranges, specifically including elderly patients, for whom such are currently lacking.METHODS: Samples were collected from subjects ranging from 20 to 98 years of age. Blood donors and clinical samples from primary care patients were used for reference interval calculation. Samples were analysed using the Advia Centaur® PIIINP assay. After exclusion of samples high in alanine transaminase (AST), aspartate transaminase (ALT), and C-reactive protein (CRP) 386 samples were used in the reference interval calculation.RESULTS AND CONCLUSION: We determined the following reference interval for the Advia Centaur® PIIINP assay: the lower limit of the reference interval (2.5% percentile with 95% CI) was 4.42 (4.20-4.65) µg/L and the upper limit of the reference interval (97.5% percentile 95% CI) 16.0 (15.04-17.02) µg/L.No significant differences in mean PIIINP concentrations were found between men and women. While differing mean PIIINP concentrations were seen among subjects in different age groups, the differences were small and partitioning of reference range was determined not to be necessary.
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- Ramji, Rathi, et al.
(författare)
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Determinants of waterpipe use amongst adolescents in Northern Sweden : a survey of use pattern, risk perception, and environmental factors
- 2015
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Ingår i: BMC Research Notes. - : BioMed Central. - 1756-0500. ; 8
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Determinants of waterpipe use in adolescents are believed to differ from those for other tobacco products, but there is a lack of studies of possible social, cultural, or psychological aspects of waterpipe use in this population. This study applied a socioecological model to explore waterpipe use, and its relationship to other tobacco use in Swedish adolescents.METHODS: A total of 106 adolescents who attended an urban high-school in northern Sweden responded to an anonymous questionnaire. Prevalence rates for waterpipe use were examined in relation to socio-demographics, peer pressure, sensation seeking behavior, harm perception, environmental factors, and depression.RESULTS: Thirty-three percent reported ever having smoked waterpipe (ever use), with 30 % having done so during the last 30 days (current use). Among waterpipe ever users, 60 % had ever smoked cigarettes in comparison to 32 % of non-waterpipe smokers (95 % confidence interval 1.4-7.9). The odds of having ever smoked waterpipe were three times higher among male high school seniors as well as students with lower grades. Waterpipe ever users had three times higher odds of having higher levels of sensation-seeking (95 % confidence interval 1.2-9.5) and scored high on the depression scales (95 % confidence interval 1.6-6.8) than non-users. The odds of waterpipe ever use were four times higher for those who perceived waterpipe products to have pleasant smell compared to cigarettes (95 % confidence interval 1.7-9.8). Waterpipe ever users were twice as likely to have seen waterpipe use on television compared to non-users (95 % confidence interval 1.1-5.7). The odds of having friends who smoked regularly was eight times higher for waterpipe ever users than non-users (95 % confidence interval 2.1-31.2).CONCLUSION: The current study reports a high use of waterpipe in a select group of students in northern Sweden. The study adds the importance of looking at socioecological determinants of use, including peer pressure and exposure to media marketing, as well as mental health among users.
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