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Träfflista för sökning "WFRF:(Johansson Morgan) "

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1.	Gusev, A, et al. (author) Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation 2016 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 7, s. 10979- Journal article (peer-reviewed)abstract Although genome-wide association studies have identified over 100 risk loci that explain ∼33% of familial risk for prostate cancer (PrCa), their functional effects on risk remain largely unknown. Here we use genotype data from 59,089 men of European and African American ancestries combined with cell-type-specific epigenetic data to build a genomic atlas of single-nucleotide polymorphism (SNP) heritability in PrCa. We find significant differences in heritability between variants in prostate-relevant epigenetic marks defined in normal versus tumour tissue as well as between tissue and cell lines. The majority of SNP heritability lies in regions marked by H3k27 acetylation in prostate adenoc7arcinoma cell line (LNCaP) or by DNaseI hypersensitive sites in cancer cell lines. We find a high degree of similarity between European and African American ancestries suggesting a similar genetic architecture from common variation underlying PrCa risk. Our findings showcase the power of integrating functional annotation with genetic data to understand the genetic basis of PrCa.
2.	Bonaca, MP, et al. (author) Long-term use of ticagrelor in patients with prior myocardial infarction 2015 In: The New England journal of medicine. - 1533-4406. ; 372:19, s. 1791-1800 Journal article (peer-reviewed)
3.	Butura, A, et al. (author) The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model 2009 In: Journal of hepatology. - : Elsevier BV. - 1600-0641 .- 0168-8278. ; 50:3, s. 572-583 Journal article (peer-reviewed)
4.	Warren, HR, et al. (author) Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk 2017 In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 49:3, s. 403-415 Journal article (peer-reviewed)
5.	2017 swepub:Mat__t
6.	Aad, G., et al. (author) 2010 swepub:Mat__t
7.	Aad, G., et al. (author) 2011 swepub:Mat__t
8.	2011 swepub:Mat__t
9.	Aad, G., et al. (author) 2010 swepub:Mat__t
10.	Aad, G., et al. (author) 2010 swepub:Mat__t

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Result 1-10 of 121

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Type of publication: journal article (62); conference paper (24); reports (23); licentiate thesis (3); doctoral thesis (1); research review (1); show more...; show less...

Type of content: peer-reviewed (74); other academic/artistic (39); pop. science, debate, etc. (1)

Author/Editor: Johansson, Morgan, 1 ... (44); Zhou, B. (15); Brenner, H (15); Trivedi, A. (14); Gudnason, V (14); Morgan, K (14); show more...; Amouyel, P (13); Plos, Mario, 1963 (13); Peters, A (12); Lehtimaki, T. (12); Tuomilehto, J. (12); Metspalu, A (12); Salomaa, V (12); Solfrizzi, V (12); Yang, Y. (11); Kim, J. (11); Riboli, E. (11); Lee, J. (11); Tzourio, C (11); Elliott, P (11); Vollenweider, P. (11); He, J (11); Koskinen, S (11); Sundstrom, J (11); Marrugat, J (11); Cameron, D. (10); Lopes, L. (10); Schumacher, M. (10); Evans, A. (10); Overvad, K (10); Diaz, A. (10); Song, Y. (10); Santos, R. (10); Chen, ZM (10); Lin, X. (10); Lind, Lars (10); Johansson, M (10); Woo, J. (10); Trichopoulos, D (10); Ikram, MA (10); Vineis, P (10); Taylor, A (10); Linneberg, A. (10); Johansson, Morgan (10); Chaturvedi, N (10); Bata, I (10); Claessens, F (10); Laatikainen, T (10); Musil, V (10); Sabanayagam, C (10); show less...

University: Chalmers University of Technology (53); Karolinska Institutet (29); Uppsala University (22); Lund University (18); University of Gothenburg (16); Umeå University (14); show more...; Royal Institute of Technology (12); Stockholm University (8); Luleå University of Technology (5); University of Skövde (5); Linköping University (4); RISE (4); Högskolan Dalarna (4); Linnaeus University (3); Kristianstad University College (1); University West (1); Jönköping University (1); Malmö University (1); Mid Sweden University (1); show less...

Language: English (96); Swedish (25)

Research subject (UKÄ/SCB): Engineering and Technology (58); Medical and Health Sciences (35); Natural sciences (12); Humanities (3); Social Sciences (1)

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