| 1. |
- Abdallah, J, et al.
(author)
-
Bose-Einstein correlations in W+W- events at LEP2
- 2005
-
In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044. ; 44:2, s. 161-174
-
Journal article (peer-reviewed)abstract
- Bose-Einstein correlations (BEC) between final state particles in the reaction e(+)e(-) -> W+ W- -> q(1)(q(2)) over barq(3)(q(4)over bar>) over bar) have been studied. Data corresponding to a total integrated luminosity of 550 pb(-1), recorded by the DELPHI detector at centre-of-mass energies ranging from 189 to 209 GeV, were analysed. An indication for inter-W BEC between like-sign particles has been found at the level of 2.4 standard deviations of the combined statistical and systematic uncertainties.
|
|
| 2. |
- Beal, Jacob, et al.
(author)
-
Robust estimation of bacterial cell count from optical density
- 2020
-
In: Communications Biology. - : Springer Science and Business Media LLC. - 2399-3642. ; 3:1
-
Journal article (peer-reviewed)abstract
- Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data.
|
|
| 3. |
- Brewington, Seth, et al.
(author)
-
Islands of change vs. islands of disaster : Managing pigs and birds in the Anthropocene of the North Atlantic
- 2015
-
In: The Holocene. - : Sage Publications. - 0959-6836 .- 1477-0911. ; 25:10, s. 1676-1684
-
Journal article (peer-reviewed)abstract
- The offshore islands of the North Atlantic were among some of the last settled places on earth, with humans reaching the Faroes and Iceland in the late Iron Age and Viking period. While older accounts emphasizing deforestation and soil erosion have presented this story of island colonization as yet another social–ecological disaster, recent archaeological and paleoenvironmental research combined with environmental history, environmental humanities, and bioscience is providing a more complex understanding of long-term human ecodynamics in these northern islands. An ongoing interdisciplinary investigation of the management of domestic pigs and wild bird populations in Faroes and Iceland is presented as an example of sustained resource management using local and traditional knowledge to create structures for successful wild fowl management on the millennial scale.
|
|
| 4. |
- Escott-Price, Valentina, et al.
(author)
-
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease
- 2014
-
In: PLOS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 9:6, s. e94661-
-
Journal article (peer-reviewed)abstract
- Background: Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls. Principal Findings: In addition to earlier reported genes, we detected genome-wide significant loci on chromosomes 8 (TP53INP1, p = 1.4x10(-6)) and 14 (IGHV1-67 p = 7.9x10(-8)) which indexed novel susceptibility loci. Significance: The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease.
|
|
| 5. |
- Gunnarsson, Claes, 1967-, et al.
(author)
-
Charge the relationships and gain loyalty effects : turning the supply link alert to IT opportunities
- 2003
-
In: European Journal of Operational Research. - Amsterdam : Elsevier. - 0377-2217 .- 1872-6860. ; 144:2, s. 257-269
-
Journal article (peer-reviewed)abstract
- The main purpose of this paper is to explore and analyze interconnected effects related to the use of IT, and in so doing, provide an understanding of integrative logistics operations in a supply chain link. We take a theoretical point of departure in the three factors of relationship investments, formalization and trust. Thereafter we will expand and elaborate these factors by discussing embedded elements and mechanisms, related to relationships and loyalty, which result in an outlined model for empirical research focused on operational and strategic partnerships. Based on an empirical analysis we propose that the use of IT, expressed as digitization, can be seen as a driving force for bridging a gap between the actual and potential pattern of integrative logistics operations in a supply chain link. Digitization activates mechanisms in trust, commitment, and solidarity, which are related to loyalty and simultaneously enable heterogeneous influences in relationship characteristics.
|
|
| 6. |
|
|
| 7. |
- Gunnarsson, Nils, et al.
(author)
-
Utvecklade leverantör - kundrelationer : Supply Link Management
- 2002
-
Reports (other academic/artistic)abstract
- Forskningsprojektets syfte är att beskriva och analysera hur en ökad produkt- och produktionsspec ialisering hos tillverkande företag päverkar innehållet i, och inriktningen i relationen till leverantörer. Särskilt fokuseras de frågor som är relevanta när informationsteknik (IT) används som ett strategiskt hjälpmedel, i syfte att utveckla integrerad logistikverksamhet mellan affärspaner. Forskningsfrågorna pekar på problemställningar kring hur IT kan användas operativt och strategiskt för att koordinera och styra materialnöden i länken mellan leverantörer och köpande företag, här beskrivet som supply l ink management med en IT-ansats. Problemställningarna speglar vilken roll IT har för partnerskapsinriktade samarbeten för integrerad logistikverksamhet i olika typer av allianser. Vidare identifieras frågor kring förändrade förutsättningar för företagens affärsprocesser i samband med att IT möjliggör en global logistikplattform för kundföretag och leverantörer.En kombination av tjugo öppna halvstrukturerade samt tio strukturerade intervjuer har genomförts. Elva intervjuer har bandats och skrivits ut for djupare analys. Även skriftlig dokumentation har inhämtats och delgivits forskarna. Inom ramen för projektet har det funnits en referensgrupp samt en styrgrupp med forskare och ansvariga foretagsrepresentanter. Sju formella möten har genomförts där dels projektets innehåll fortlöpande stämts av, dels riktlinjer för fonsatt utveckling diskuterats. Till mötena har underlag för diskussion skapats i form av tre skrivna företagsrapporter. Forskare och företagsrepresentanter har samverkat i en interaktiv forskningsdesign där förtrogenhetskunskap successivt byggts upp och utnyttjats.Resultaten pekar på att e-business applikationer genererar lojalitetseffekter som är av omedelbar relevans för operativa och forsörjningsstrategiska överväganden au utveckla integrerad logistikverksamhet och samarbete mellan leverantörer och kunder. Olika lojalitetseffekter kan aktualiseras beroende på hur få retagen väljer att utveckla relationerna. Ytterligare resultat markerar hur Internet-teknikens tillämpning i allianser spelar en väsentlig roll för insourcing av kompetenser, åtgärder for all öka kundupplevt värde respektive operativ effektivitet. Policyrelevanta implikationer kan identifieras där IT stärker och stabiliserar logistikens funktion för mindre leverantörer i nätverk. Förändrade försörjningsstrategier och logistikstruktur bryter om leverantörshierarkier, och genererar genomgripande omflyttningar i värdekedjan. IT kan även möjliggöra en effektiv kommunikationsplattform samt en utvidgad roll för systemleverantörer med framskjuten position.
|
|
| 8. |
|
|
| 9. |
- Jones, Lesley, et al.
(author)
-
Convergent genetic and expression data implicate immunity in Alzheimer's disease
- 2015
-
In: Alzheimer's & Dementia. - : Wiley. - 1552-5260 .- 1552-5279. ; 11:6, s. 658-671
-
Journal article (peer-reviewed)abstract
- Background: Late-onset Alzheimer's disease (AD) is heritable with 20 genes showing genome-wide association in the International Genomics of Alzheimer's Project (IGAP). To identify the biology underlying the disease, we extended these genetic data in a pathway analysis. Methods: The ALIGATOR and GSEA algorithms were used in the IGAP data to identify associated functional pathways and correlated gene expression networks in human brain. Results: ALIGATOR identified an excess of curated biological pathways showing enrichment of association. Enriched areas of biology included the immune response (P = 3.27 X 10(-12) after multiple testing correction for pathways), regulation of endocytosis (P = 1.31 X 10(-11)), cholesterol transport (P = 2.96 X 10(-9)), and proteasome-ubiquitin activity (P = 1.34 X 10(-6)). Correlated gene expression analysis identified four significant network modules, all related to the immune response (corrected P = .002-.05). Conclusions: The immime response, regulation of endocytosis, cholesterol transport, and protein ubiquitination represent prime targets for AD therapeutics.
|
|
| 10. |
- Jonsson, Seth
(author)
-
Business negotiations in the electronic commerce world
-
Other publication (other academic/artistic)abstract
- The changes in business negotations, when transforming more activites into Internet electronic commerce, are the primare focus in the article. Three interaction models are the basis of the discussion: face-to-face negotiations, reverse e-auctions, and e-agents. Data are examined with a negotiation strategy model, previously evolved by the author. The findings indicate that automated negotiations have a great potential to support or rearrange the long-established negotiation design. Using the e-auction model competently adds up to supplier base competitiveness, better prices, and lowered administrative costs. E-agents are inspiring and may create a future evolution in e-negotiation, although they still are at an infancy stage.
|
|
