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1.	Kanai, M, et al. (author) 2023 swepub:Mat__t
2.	Niemi, MEK, et al. (author) 2021 swepub:Mat__t
3.	Pathak, GA, et al. (author) A first update on mapping the human genetic architecture of COVID-19 2022 In: Nature. - : Springer Science and Business Media LLC. - 1476-4687 .- 0028-0836. ; 608:7921, s. E1-E10 Journal article (other academic/artistic)
4.	Oprea, Tudor I, et al. (author) Unexplored therapeutic opportunities in the human genome 2018 In: Nature Reviews Drug Discovery. - : Springer Science and Business Media LLC. - 1474-1776 .- 1474-1784. ; 17:5, s. 317-332 Journal article (peer-reviewed)abstract A large proportion of biomedical research and the development of therapeutics is focused on a small fraction of the human genome. In a strategic effort to map the knowledge gaps around proteins encoded by the human genome and to promote the exploration of currently understudied, but potentially druggable, proteins, the US National Institutes of Health launched the Illuminating the Druggable Genome (IDG) initiative in 2014. In this article, we discuss how the systematic collection and processing of a wide array of genomic, proteomic, chemical and disease-related resource data by the IDG Knowledge Management Center have enabled the development of evidence-based criteria for tracking the target development level (TDL) of human proteins, which indicates a substantial knowledge deficit for approximately one out of three proteins in the human proteome. We then present spotlights on the TDL categories as well as key drug target classes, including G protein-coupled receptors, protein kinases and ion channels, which illustrate the nature of the unexplored opportunities for biomedical research and therapeutic development.
5.	Cui, J, et al. (author) Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy 2010 In: Arthritis and rheumatism. - : Wiley. - 1529-0131 .- 0004-3591. ; 62:7, s. 1849-1861 Journal article (peer-reviewed)
6.	Diogo, D, et al. (author) TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits 2015 In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 10:4, s. e0122271- Journal article (peer-reviewed)
7.	Herlitz, J, et al. (author) Effect of metoprolol on death and cardiac events during a 2-year period after coronary artery bypass grafting. The MACB Study Group 1995 In: European heart journal. - 0195-668X. ; 16:12, s. 1825-1832 Journal article (peer-reviewed)
8.	Liu, L, et al. (author) Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits 2023 In: Nature communications. - 2041-1723. ; 14:1, s. 655- Journal article (other academic/artistic)
9.	Meister, Mikael, 1969, et al. (author) High-energy breakup of 8B 2003 In: Nucl. Phys. A. ; 718, s. 431-433 Conference paper (peer-reviewed)
10.	Nicholls, S. J., et al. (author) Assessment of omega-3 carboxylic acids in statin-treated patients with high levels of triglycerides and low levels of high-density lipoprotein cholesterol: Rationale and design of the STRENGTH trial 2018 In: Clinical Cardiology. - : Wiley. - 0160-9289. ; 41:10, s. 1281-1288 Journal article (peer-reviewed)

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Type of publication: journal article (140); conference paper (15); other publication (2); doctoral thesis (2)

Type of content: peer-reviewed (139); other academic/artistic (20)

Author/Editor: Herlitz, Johan (39); Karlson, BW (39); Lindqvist, J (30); Karlson, EW (28); Borg-Karlson, Anna-K ... (24); Karlson, Björn W., 1 ... (20); show more...; Sjölin, M (20); KLARESKOG, L (19); Alfredsson, L (15); Plenge, RM (15); Cui, J. (15); Raychaudhuri, S (14); Padyukov, L (11); Gregersen, PK (11); Costenbader, KH (10); Shadick, NA (10); Weinblatt, ME (10); Nicholls, S. J. (10); Barter, P. J. (10); Engdahl, J (9); Palmer, M. K. (9); Criswell, LA (8); Ding, B. (8); Lundman, P (8); Daly, MJ (8); Borg-Karlson, A-K (8); Bång, A (8); Askling, J (7); Worthington, J (6); De Vries, N (6); Kallberg, H (6); Karlson-Stiber, C (6); Mustaparta, H. (6); Toes, REM (6); Tak, PP (6); Crusius, JBA (6); Seldin, MF (6); Okada, Y. (5); Khan, A. (5); Lee, AT (5); Jiang, X. (5); Karlsson, T (5); Huizinga, TWJ (5); Neale, BM (5); Barton, A. (5); Sparks, JA (5); van der Horst-Bruins ... (5); Wolbink, GJ (5); Faldt, J. (5); Remmers, EF (5); show less...

University: Karolinska Institutet (54); University of Borås (42); University of Gothenburg (27); Royal Institute of Technology (26); Stockholm University (19); Lund University (8); show more...; Uppsala University (6); Linköping University (4); Chalmers University of Technology (4); Linnaeus University (4); Umeå University (3); Mid Sweden University (3); show less...

Language: English (158); Undefined language (2); Swedish (1)

Research subject (UKÄ/SCB): Medical and Health Sciences (33); Natural sciences (29); Engineering and Technology (2); Agricultural Sciences (1)

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