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  • Evans, William J, et al. (author)
  • Effect of recombinant human growth hormone on exercise capacity in patients with HIV-associated wasting on HAART.
  • 2005
  • In: The AIDS reader. - 1053-0894. ; 15:6
  • Journal article (peer-reviewed)abstract
    • Over 700 patients with HIV-associated wasting while receiving HAART were randomly assigned to double-blind treatment for 12 weeks with recombinant human growth hormone (rhGH) daily or on alternate days, or to placebo. Maximum exercise intensity increased by a median of 2.35kJ in the alternate-days group and 2.60 kJ in the daily group but decreased by 0.25kJ in the placebo group. The median difference between the daily and placebo groups was 2.85 kJ (P < .0001). These improvements suggest that rhGH treatment may enable patients with wasting to perform activities of daily living that would be exhausting without rhGH treatment.
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