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Träfflista för sökning "WFRF:(Kubiak Szeligowska Anna B.) "

Search: WFRF:(Kubiak Szeligowska Anna B.)

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  • Bartoszek, Krzysztof, et al. (author)
  • Predicting pathogenicity behavior in Escherichia coli population through a state dependent model and TRS profiling
  • 2018
  • In: PloS Computational Biology. - : PUBLIC LIBRARY SCIENCE. - 1553-734X .- 1553-7358. ; 14:1
  • Journal article (peer-reviewed)abstract
    • The Binary State Speciation and Extinction (BiSSE) model is a branching process based model that allows the diversification rates to be controlled by a binary trait. We develop a general approach, based on the BiSSE model, for predicting pathogenicity in bacterial populations from microsatellites profiling data. A comprehensive approach for predicting pathogenicity in E. coli populations is proposed using the state-dependent branching process model combined with microsatellites TRS-PCR profiling. Additionally, we have evaluated the possibility of using the BiSSE model for estimating parameters from genetic data. We analyzed a real dataset (from 251 E. coli strains) and confirmed previous biological observations demonstrating a prevalence of some virulence traits in specific bacterial sub-groups. The method may be used to predict pathogenicity of other bacterial taxa.
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  • Result 1-1 of 1
Type of publication
journal article (1)
Type of content
peer-reviewed (1)
Author/Editor
Bartoszek, Krzysztof (1)
Majchrzak, Marta (1)
Sakowski, Sebastian (1)
Kubiak-Szeligowska, ... (1)
Kaj, Ingemar, 1957- (1)
Parniewski, Pawel (1)
University
Uppsala University (1)
Linköping University (1)
Language
English (1)
Research subject (UKÄ/SCB)
Natural sciences (1)
Year
2018 (1)

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