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- Georgiev, Ivelin, 1995-
(author)
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Studies of the intergalactic medium during the Epoch of Reionization : Understanding observational probes with simulations
- 2024
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Doctoral thesis (other academic/artistic)abstract
- The first billion years of the Universe is a unique era, marked by the formation of the first stars, galaxies, and accreting black holes, which release ionising radiation into the intergalactic medium (IGM). As a result, these luminous sources initiate a period during which the cold and dense IGM, primarily consisting of neutral hydrogen (HI), is heated and ionised. We refer to this era as the Epoch of Reionization (EoR). The EoR is a global phase transition that is not trivial to observe or model computationally. It is a multi-scale event that evolves with time and depends on the nature of the astrophysical processes that govern the formation of stars and galaxies, as well as the fundamental cosmology that defines the properties of the large-scale IGM. While various measurements of cosmic reionization exist, presently they are too few to constrain the entirety of the process. However, observations from the James Webb Space Telescope and the Square Kilometre Array (SKA), among others, will provide new insight into the process. Particularly, the SKA will observe the power spectrum (PS) of the 21 cm signal from the EoR, which originates from the hyperfine transition of neutral hydrogen atoms HI in the IGM that can emit 21 cm photons. In Paper I, we investigate the evolution of the 21 cm PS across the EoR by perturbing the signal and studying its composing terms. We highlight the importance higher-order terms play in shaping the PS on large scales and quantify its evolution. Crucially, we find a characteristic length scale within the 21 cm PS, determined by the mean free path ionising photons travel in the IGM (MFP). Hence, the 21 cm PS has two regimes. We show that the large-scale signal is a biased version of the cosmological density field, and the small-scale PS is determined by the astrophysics of reionization. In Paper II, we use the decomposition of the 21 cm PS and relate it to the PS of the free electron density field. Thus, we analytically connect the 21 cm observable to a probe of the free electron density field. Such a probe is the patchy kinetic Sunyaev-Zel'dovich effect (pkSZ), observed as a foreground to the primary cosmic microwave background temperature anisotropies on small scales. The pkSZ is an integrated probe sensitive to the duration of the EoR and the characteristic size of ionised bubbles. We construct a forecast study of both probes. We show that inferences from 21 cm PS from the SKA can be verified when combined with the pkSZ observation, as each data set is influenced by different systematics. In Paper III, we focus on the modelling of the MFP within large-scale simulations, focusing on the end of reionization (EndEoR). The MFP of ionising photons is inferred from quasar data and depends on several factors. In the post-EoR era, it depends on the distribution and evolution of Lyman Limit systems (LLS), small-scale absorbers that are typically not resolved in large-scale simulations. We investigate the assumptions needed to accurately model the LLS in simulations, and we study their impact on the observables at the EndEoR. We find that LLS modelling has a profound impact on the duration of the final stages of the EoR, the shape of the 21 cm PS as well as other observables of the ionised IGM inferred from quasar spectra, such as the Ultraviolet Background of ionising photons, the effective optical depth of Lyman alpha photons, and the MFP of ionising photons.
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| 2. |
- Upadhayaya, Shankar, et al.
(author)
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Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis
- 2009
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In: Bioorganic & Medicinal Chemistry. - : Elsevier BV. - 0968-0896 .- 1464-3391. ; 17:13, s. 4681-4692
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Journal article (peer-reviewed)abstract
- A new series of 20 quinoline derivatives possessing triazolo, ureido and thioureido substituents have been synthesized and their antimycobacterial properties have been evaluated. Compounds 10, 22 and 24 inhibited Mycobacterium tuberculosis H37Rv up to 96%, 98% and 94% respectively, at a fixed concentration of 6.25 mu g/mL. Minimum inhibitory concentration of 3.125 mu g/mL was obtained for compound 10 and 24, while for compound 22 it was 6.25 mu g/mL. Molecular docking calculations suggest critical hydrogen bonding and electrostatic interactions between polar functional groups (such as quinoline-nitrogen, urea-carbonyl and hydroxyl) of anti-mycobacterial (anti-TB) compounds and amino acids (Arg186 and Glu61) of ATP-synthase of M. tuberculosis, could be the probable reason for observed anti-mycobacterial action. (C) 2009 Elsevier Ltd. All rights reserved.
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| 3. |
- Zhu, Yongda, et al.
(author)
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Probing Ultralate Reionization: Direct Measurements of the Mean Free Path over 5 z
- 2023
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In: Astrophysical Journal. - 1538-4357 .- 0004-637X. ; 955:2
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Journal article (peer-reviewed)abstract
- The mean free path of ionizing photons, lambda(mfp), is a critical parameter for modeling the intergalactic medium (IGM) both during and after reionization. We present direct measurements of lambda(mfp) from QSO spectra over the redshift range 5 < z < 6, including the first measurements at z similar or equal to 5.3 and 5.6. Our sample includes data from the XQR-30 VLT large program, as well as new Keck/ESI observations of QSOs near z similar to 5.5, for which we also acquire new [C II] 158 mu m redshifts with ALMA. By measuring the Lyman continuum transmission profile in stacked QSO spectra, we find lambda(mfp) = 9.33(-1.80)(+2.06), 5.40(-1.40)(+1.47), 3.31(-1.34)(+2.74), and 0.81(-0.48)(+0.73) pMpc at z = 5.08, 5.31, 5.65, and 5.93, respectively. Our results demonstrate that lambda(mfp) increases steadily and rapidly with time over 5 < z < 6. Notably, we find that lambda(mfp) deviates significantly from predictions based on a fully ionized and relaxed IGM as late as z = 5.3. By comparing our results to model predictions and indirect lambda(mfp) constraints based on IGM Ly alpha opacity, we find that the evolution of lambda(mfp) is consistent with scenarios wherein the IGM is still undergoing reionization and/or retains large fluctuations in the ionizing UV background well below redshift 6.
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