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Träfflista för sökning "WFRF:(Lööv A) "

Search: WFRF:(Lööv A)

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1.
  • Alföldy, B., et al. (author)
  • Measurements of air pollution emission factors for marine transportation in SECA
  • 2013
  • In: Atmospheric Measurement Techniques. - : Copernicus GmbH. - 1867-1381 .- 1867-8548. ; 6:7, s. 1777-1791
  • Journal article (peer-reviewed)abstract
    • The chemical composition of the plumes of seagoing ships was measured during a two week long measurement campaign in the port of Rotterdam, Hoek van Holland The Netherlands, in September 2009. Altogether, 497 ships were monitored and a statistical evaluation of emission factors (g kg(-1) fuel) was provided. The concerned main atmospheric components were SO2, NO2, NOx and the aerosol particle number. In addition, the elemental and water-soluble ionic composition of the emitted particulate matter was determined. Emission factors were expressed as a function of ship type, power and crankshaft rotational speed. The average SO2 emission factor was found to be roughly half of what is allowed in sulphur emission control areas (16 vs. 30 g kg(-1) fuel), and exceedances of this limit were rarely registered. A significant linear relationship was observed between the SO2 and particle number emission factors. The intercept of the regression line, 4.8 x 10(15) (kg fuel)(-1), gives the average number of particles formed during the burning of 1 kg zero sulphur content fuel, while the slope, 2 x 10(18), provides the average number of particles formed with 1 kg sulphur burnt with the fuel. Water-soluble ionic composition analysis of the aerosol samples from the plumes showed that similar to 144 g of particulate sulphate was emitted from 1 kg sulphur burnt with the fuel. The mass median diameter of sulphate particles estimated from the measurements was similar to 42 nm.
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2.
  • Hanlon, Killian S., et al. (author)
  • High levels of AAV vector integration into CRISPR-induced DNA breaks
  • 2019
  • In: Nature Communications. - : NATURE PUBLISHING GROUP. - 2041-1723. ; 10
  • Journal article (peer-reviewed)abstract
    • Adeno-associated virus (AAV) vectors have shown promising results in preclinical models, but the genomic consequences of transduction with AAV vectors encoding CRISPR-Cas nucleases is still being examined. In this study, we observe high levels of AAV integration (up to 47%) into Cas9-induced double-strand breaks (DSBs) in therapeutically relevant genes in cultured murine neurons, mouse brain, muscle and cochlea. Genome-wide AAV mapping in mouse brain shows no overall increase of AAV integration except at the CRISPR/Cas9 target site. To allow detailed characterization of integration events we engineer a miniature AAV encoding a 465 bp lambda bacteriophage DNA (AAV-lambda 465), enabling sequencing of the entire integrated vector genome. The integration profile of AAV-465 lambda in cultured cells display both full-length and fragmented AAV genomes at Cas9 on-target sites. Our data indicate that AAV integration should be recognized as a common outcome for applications that utilize AAV for genome editing.
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4.
  • Hansson, S. O., et al. (author)
  • Policycykeln : En modell för beslutsprocesser i miljöfrågor
  • 2006
  • In: Karin Edvardsson och Sven Ove Hansson (red), Vägar till ett effektivt miljöarbete. - Umeå : Boréa bokförlag. - 9189140478
  • Book chapter (other academic/artistic)abstract
    • I kapitlet diskuteras utifrån policyprocessens olika steg hur beslutsprocesser inom miljöområdet kan och bör studeras.
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  • Result 1-5 of 5

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