| 1. |
- Hellberg, Christel, et al.
(author)
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Evidence and evidence gaps in assessments and interventions in areas related to social work research and practice – an overview of four evidence maps : [Vetenskapligt kunskapsläge om utredning och insatser i socialt arbete och forskning –en sammanställning av fyra kartläggningar]
- 2023
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In: European Journal of Social Work. - : Informa UK Limited. - 1369-1457 .- 1468-2664. ; 26:5, s. 882-895
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Journal article (peer-reviewed)abstract
- This overview of four evidence maps is based on systematic reviews of assessment and interventions in social work practice. The aim was to investigate the evidence and evidence gaps within four important areas for social work research and practice. Descriptive data on search strategies and domains were collected from four evidence maps, on Social Assistance, Substance Dependence, Care for older adults respectively for persons with disabilities. The scientific quality and scientific evidence were assessed. Key findings were summarised by analyzing and discussing common and specific elements in the evidence maps. The overview was undertaken in close collaboration between researchers with expertise in the field and a government agency. The overview identified both evidence and evidence gaps with respect to effects and experiences of interventions and assessment methods in four evidence maps. Evidence maps provide a comprehensive picture of the state of social services research and can thereby be of use to both researchers and practitioners, and in the production of evidence based social work.
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| 2. |
- Andréasson, Maia, 1960, et al.
(author)
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På jakt efter amerikasvenskan
- 2013
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In: Svenskans beskrivning / [SvB.] 32, Förhandlingar vid trettioandra sammankomsten för svenskans beskrivning, Karlstad den 13-14 oktober 2011 / redigerade av Björn Bihl, Peter Andersson & Lena Lötmarker. - Karlstad : Karlstads universitet. - 1102-3619. - 9789170634901 ; 32, s. 82-91
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Conference paper (peer-reviewed)
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| 3. |
- Hadrévi, Jenny, 1977-, et al.
(author)
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Comparative metabolomics of muscle interstitium fluid in human trapezius myalgia: an in vivo microdialysis study
- 2013
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In: European Journal of Applied Physiology. - : Springer Verlag (Germany). - 1439-6319 .- 1439-6327. ; 113:12, s. 2977-2989
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Journal article (peer-reviewed)abstract
- The mechanisms behind trapezius myalgia are unclear. Many hypotheses have been presented suggesting an altered metabolism in the muscle. Here, muscle microdialysate from healthy and myalgic muscle is analysed using metabolomics. Metabolomics analyse a vast number of metabolites, enabling a comprehensive explorative screening of the cellular processes in the muscle. less thanbrgreater than less thanbrgreater thanMicrodialysate samples were obtained from the shoulder muscle of healthy and myalgic subjects that performed a work and stress test. Samples from the baseline period and from the recovery period were analysed using gas chromatography-mass spectrometry (GC-MS) together with multivariate analysis to detect differences in extracellular content of metabolites between groups. Systematic differences in metabolites between groups were identified using multivariate analysis and orthogonal partial least square discriminate analysis (OPLS-DA). A complementary Mann-Whitney U test of group difference in individual metabolites was also performed. less thanbrgreater than less thanbrgreater thanA large number of metabolites were detected and identified in this screening study. At baseline, no systematic differences between groups were observed according to the OPLS-DA. However, two metabolites, l-leucine and pyroglutamic acid, were significantly more abundant in the myalgic muscle compared to the healthy muscle. In the recovery period, systematic difference in metabolites between the groups was observed according to the OPLS-DA. The groups differed in amino acids, fatty acids and carbohydrates. Myristic acid and putrescine were significantly more abundant and beta-d-glucopyranose was significantly less abundant in the myalgic muscle. less thanbrgreater than less thanbrgreater thanThis study provides important information regarding the metabolite content, thereby presenting new clues regarding the pathophysiology of the myalgic muscle.
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| 4. |
- Hadrévi, Jenny, 1977-, et al.
(author)
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Multivariate Modeling of Proteins Related to Trapezius Myalgia, a Comparative Study of Female Cleaners with or without Pain
- 2013
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In: PLOS ONE. - : Public Library of Science. - 1932-6203. ; 8:9, s. e73285-
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Journal article (peer-reviewed)abstract
- The prevalence of chronic trapezius myalgia is high in women with high exposure to awkward working positions, repetitive movements and movements with high precision demands. The mechanisms behind chronic trapezius myalgia are not fully understood. The purpose of this study was to explore the differences in protein content between healthy and myalgic trapezius muscle using proteomics. Muscle biopsies from 12 female cleaners with work-related trapezius myalgia and 12 pain free female cleaners were obtained from the descending part of the trapezius. Proteins were separated with two-dimensional differential gel electrophoresis (2D-DIGE) and selected proteins were identified with mass spectrometry. In order to discriminate the two groups, quantified proteins were fitted to a multivariate analysis: partial least square discriminate analysis. The model separated 28 unique proteins which were related to glycolysis, the tricaboxylic acid cycle, to the contractile apparatus, the cytoskeleton and to acute response proteins. The results suggest altered metabolism, a higher abundance of proteins related to inflammation in myalgic cleaners compared to healthy, and a possible alteration of the contractile apparatus. This explorative proteomic screening of proteins related to chronic pain in the trapezius muscle provides new important aspects of the pathophysiology behind chronic trapezius myalgia.
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| 5. |
- Johansson, Malin E V, 1971, et al.
(author)
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Composition and functional role of the mucus layers in the intestine.
- 2011
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In: Cellular and Molecular Life Sciences. - : Springer Science and Business Media LLC. - 1420-682X .- 1420-9071. ; 68, s. 3635-3641
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Research review (peer-reviewed)abstract
- In discussions on intestinal protection, the protective capacity of mucus has not been very much considered. The progress in the last years in understanding the molecular nature of mucins, the main building blocks of mucus, has, however, changed this. The intestinal enterocytes have their apical surfaces covered by transmembrane mucins and the whole intestinal surface is further covered by mucus, built around the gel-forming mucin MUC2. The mucus of the small intestine has only one layer, whereas the large intestine has a two-layered mucus where the inner, attached layer has a protective function for the intestine, as it is impermeable to the luminal bacteria.
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| 6. |
- Larsson, Ida, 1977, et al.
(author)
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Amerikasvenskan förr och nu
- 2012
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In: Norsk lingvistisk tidskrift. - 0800-3076. ; 30:2, s. 263-286
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Journal article (peer-reviewed)abstract
- Denna artikel jämför dagens amerikasvenska med den som talades för 50 år sedan. Utifrån material som samlats in i Minnesota 2011 och material som samlades in under 1960-talet diskuteras dialektdrag, andraspråksdrag och, slutligen, vad som kan sägas utmärka den amerikasvenska som talas idag. Artikeln vill belysa ämnet ur flera möjliga infallsvinklar, blottlägga några av de processer som är inblandade och skissera några huvudlinjer i utvecklingen av amerikasvenskan.
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| 7. |
- Larsson, Ida, 1977-, et al.
(author)
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Amerikasvenskan förr och nu
- 2012
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In: Norsk Lingvistisk Tidsskrift. - Oslo : Novus Forlag. - 0800-3076 .- 2387-6719. ; 30:2, s. 263-286
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Journal article (peer-reviewed)
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| 8. |
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| 9. |
- Nilsdotter-Augustinsson, Åsa, 1962-, et al.
(author)
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Staphylococcus aureus, but not Staphylococcus epidermidis, modulates the oxidative response and induces apoptosis in human neutrophils
- 2004
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In: Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). - : Wiley. - 0903-4641 .- 1600-0463. ; 112:2, s. 109-118
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Journal article (peer-reviewed)abstract
- S. epidermidis is the most common isolate in foreign body infections. The aim of this study was to understand why S. epidermidis causes silent biomaterial infections. In view of the divergent inflammatory responses S. epidermidis and S. aureus cause in patients, we analyzed how they differ when interacting with human neutrophils. Neutrophils interacting with S. epidermidis strains isolated either from granulation tissue covering infected hip prostheses or from normal skin flora were tested by measuring the oxidative response as chemiluminescence and apoptosis as annexin V binding. Different S. aureus strains were tested in parallel. All S. epidermidis tested were unable to modulate the oxidative reaction in response to formyl-methionyl-leucyl-phenylalanine (fMLP) and did not provoke, but rather inhibited, apoptosis. In contrast, some S. aureus strains enhanced the oxidative reaction, and this priming capacity was linked to p38-mitogen-activated-protein-kinase (p38-MAPK) activation and induction of apoptosis. Our results may explain why S. epidermidis is a weak inducer of inflammation compared to S. aureus, and therefore responsible for the indolent and chronic course of S. epidermidis biomaterial infections.
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| 10. |
- Yu, Tianyi, 1989-, et al.
(author)
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Traffic Situation Estimator for Adaptive Cruise Control
- 2016
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In: 2016 IEEE 17th International Symposium on A World of Wireless, Mobile and Multimedia Networks (WoWMoM). - Piscataway, NJ : IEEE. - 9781509021857 - 9781509021840
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Conference paper (peer-reviewed)abstract
- A traffic situation estimator capable of analyzing driving behavior utilizing an image analysis-based tracking module is presented. The behavior is analyzed by using a state machine driven counter to estimate the traffic rhythm and determine if the detected vehicles are approaching, getting away, have been overtaken or have overtaken the ego-vehicle. Depending on the result, the traffic situation estimator suggest different reactions, either to drive faster, slower or optionally suggest to overtake vehicles ahead to help the driver to follow the traffic rhythm which in turn will improve safety and energy efficiency. The proposed approach is implemented in a smart-phone and has shown good performance while testing the application on a two-lane highway. © 2016 IEEE.
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