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Träfflista för sökning "WFRF:(Lee Chanwook) "

Search: WFRF:(Lee Chanwook)

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1.
  • Lee, James J, et al. (author)
  • Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
  • 2018
  • In: Nature genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 50:8, s. 1112-1121
  • Journal article (peer-reviewed)abstract
    • Here we conducted a large-scale genetic association analysis of educational attainment in a sample of approximately 1.1million individuals and identify 1,271independent genome-wide-significant SNPs. For the SNPs taken together, we found evidence of heterogeneous effects across environments. The SNPs implicate genes involved in brain-development processes and neuron-to-neuron communication. In a separate analysis of the X chromosome, we identify 10independent genome-wide-significant SNPs and estimate a SNP heritability of around 0.3% in both men and women, consistent with partial dosage compensation. A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11-13% of the variance in educational attainment and 7-10% of the variance in cognitive performance. This prediction accuracy substantially increases the utility of polygenic scores as tools in research.
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2.
  • Lindqvist, Erik, et al. (author)
  • Financial Windfalls, Portfolio Allocations, and Risk Preferences
  • 2023
  • Reports (other academic/artistic)abstract
    • We investigate the impact of financial windfalls on household portfolio choices and risk exposure. Exploiting the randomized assignment of lottery prizes in three Swedish lotteries, we find a windfall gain of $100K leads to a 5-percentage-point de- crease in the risky share of household portfolios. We show theoretically that negative wealth effects are consistent with both constant and decreasing relative risk aversion and analyze how our empirical estimates help distinguish between competing models of portfolio choice. We further show our results are quantitatively aligned with the predictions of a calibrated dynamic portfolio choice model with nontradable human capital and consumption habits. 
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reports (1)
journal article (1)
Type of content
other academic/artistic (1)
peer-reviewed (1)
Author/Editor
Cesarini, David (2)
Jacobsson, Bo, 1960 (1)
Johannesson, Magnus (1)
Campbell, Harry (1)
Oskarsson, Sven, 197 ... (1)
Wareham, Nicholas J. (1)
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Koellinger, Philipp ... (1)
Langenberg, Claudia (1)
Magnusson, Patrik K ... (1)
Lee, James J. (1)
Wu, Yang (1)
Luan, Jian'an (1)
Metspalu, Andres (1)
Wilson, James F. (1)
Li, Hui (1)
Östling, Robert (1)
Zhao, Jing Hua (1)
Porteous, David J (1)
Hayward, Caroline (1)
Kumari, Meena (1)
Conley, Dalton C (1)
Beauchamp, Jonathan ... (1)
Kleinman, Aaron (1)
Karlsson- Linnér, Ri ... (1)
Harris, Kathleen Mul ... (1)
Milani, Lili (1)
Esko, Tõnu (1)
Herd, Pamela (1)
Freese, Jeremy (1)
Visscher, Peter M. (1)
Meyer, Michelle N (1)
Benjamin, Daniel J. (1)
Turley, Patrick (1)
Okbay, Aysu (1)
Furlotte, Nicholas A (1)
Tung, Joyce Y. (1)
Day, Felix R. (1)
Yang, Jian (1)
Ong, Ken K. (1)
Lindqvist, Erik (1)
Briggs, Joseph (1)
Pers, Tune H. (1)
Mägi, Reedik (1)
Perry, John R.B. (1)
Robinson, Matthew R. (1)
Alver, Maris (1)
Smith, Blair H. (1)
Yengo, Loic (1)
Ritchie, Marylyn D. (1)
Joshi, Peter K (1)
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University
Stockholm School of Economics (2)
University of Gothenburg (1)
Uppsala University (1)
Stockholm University (1)
Karolinska Institutet (1)
Language
English (2)
Research subject (UKÄ/SCB)
Natural sciences (1)
Medical and Health Sciences (1)
Social Sciences (1)

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