| 1. |
- Batani, D., et al.
(author)
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Effects of laser prepulses on laser-induced proton generation
- 2010
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In: New Journal of Physics. - : IOP Publishing. - 1367-2630. ; 12
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Journal article (peer-reviewed)abstract
- Low-intensity laser prepulses (<10(13) W cm(-2), nanosecond duration) are a major issue in experiments on laser-induced generation of protons, often limiting the performances of proton sources produced by high-intensity lasers (approximate to 10(19) W cm(-2), picosecond or femtosecond duration). Depending on the intensity regime, several effects may be associated with the prepulse, some of which are discussed in this paper: (i) destruction of thin foil targets by the shock generated by the laser prepulse; (ii) creation of preplasma on the target front side affecting laser absorption; (iii) deformation of the target rear side; and (iv) whole displacement of thin foil targets affecting the focusing condition. In particular, we show that under oblique high-intensity irradiation and for low prepulse intensities, the proton beam is directed away from the target normal. Deviation is towards the laser forward direction, with an angle that increases with the level and duration of the ASE pedestal. Also, for a given laser pulse, the beam deviation increases with proton energy. The observations are discussed in terms of target normal sheath acceleration, in combination with a laser-controllable shock wave locally deforming the target surface.
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| 3. |
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| 4. |
- Backman, Linda, et al.
(author)
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Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up : A Case Report
- 2022
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In: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 37:2, s. 531-543
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Journal article (peer-reviewed)abstract
- Objective: To elaborate on possible cognitive sequelae related to COVID-19, associated cerebrovascular injuries as well as the general consequences from intensive care. COVID-19 is known to have several, serious CNS-related consequences, but neuropsychological studies of severe COVID-19 are still rare.Methods: M., a 45-year-old man, who survived a severe COVID-19 disease course including Acute Respiratory Distress Syndrome (ARDS), cerebral microbleeds, and 35 days of mechanical ventilation, is described. We elaborate on M’s recovery and rehabilitation process from onset to the 8-month follow-up. The cognitive functions were evaluated with a comprehensive screening battery at 4 weeks after extubation and at the 8-month follow-up.Results: Following extubation, M. was delirious, reported visual hallucinations, and had severe sleeping difficulties. At about 3 months after COVID-19 onset, M. showed mild to moderate deficits on tests measuring processing speed, working memory, and attention. At assessments at 8 months, M. performed better, with results above average on tests measuring learning, memory, word fluency, and visuospatial functions. Minor deficits were still found regarding logical reasoning, attention, executive functioning, and processing speed. There were no lingering psychiatric symptoms. While M. had returned to a part-time job, he was not able to resume previous work-tasks.Conclusion: This case-study demonstrates possible cognitive deficits after severe COVID-19 and emphasizes the need of a neuropsychological follow-up, with tests sensitive to minor deficits. The main findings of this report provide some support that the long-term prognosis for cognition in severe COVID-19 may be hopeful.
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| 5. |
- Batani, D., et al.
(author)
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Effects of laser prepulse on proton generation
- 2010
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In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. - : Elsevier BV. - 0168-9002. ; 620:1, s. 76-82
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Conference paper (peer-reviewed)abstract
- Low-intensity laser prepulse ( < 10(13) W/cm(2), ns duration) are a major issue in experiments on laser-generation of protons, often limiting the performances of proton sources produced by high-intensity lasers (approximate to 10(19) W/cm(2), ps or fs duration) Several effects are associated to the prepulse and are discussed in this contribution: i) Destruction of thin foil targets by the shock generated by the laser prepulse ii) Creation of preplasma on target front side affecting laser absorption iii) Deformation of target rear side iv) Whole displacement of thin foil targets affecting focusing condition In particular, we show that under oblique high-intensity irradiation and for low prepulse intensities, the proton beam is directed away from the target normal. Deviation is towards the laser forward direction, with an angle that increases with the level and duration of the ASE pedestal. Also, for a given laser pulse, beam deviation increases with proton energy. The observations are discussed in terms of Target Normal Sheath Acceleration, in combination with a laser-controllable shock wave locally deforming the target surface. (C) 2010 Elsevier B.V. All rights reserved.
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| 6. |
- Batani, D., et al.
(author)
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Effects of laser prepulse on proton generation
- 2010
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In: Radiation Effects and Defects in Solids. - : Informa UK Limited. - 1042-0150 .- 1029-4953. ; 165:6-10, s. 794-802
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Conference paper (peer-reviewed)abstract
- Prepulse is a major issue for laser generation of protons, often limiting the performances of laser sources. Here, we show the use of prepulse (1013W/cm2, ns duration) to actively manipulate the proton beam direction. Under oblique high-intensity irradiation (approximate to 1019W/cm2, ps duration) of the thin foil target, and for low prepulse intensities, the proton beam is directed away from the ounperturbedo target normal. Observations are discussed in terms of target normal sheath acceleration, in combination with a laser-controllable shock locally deforming the target surface.
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| 7. |
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| 8. |
- Carroll, DC, et al.
(author)
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Active manipulation of the spatial energy distribution of laser-accelerated proton beams
- 2007
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In: Physical Review E (Statistical, Nonlinear, and Soft Matter Physics). - 1539-3755. ; 76:065401(R), s. 1-065401
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Journal article (peer-reviewed)abstract
- The spatial energy distributions of beams of protons accelerated by ultrahigh intensity (>10^19 W/cm2) picosecond laser pulse interactions with thin foil targets are investigated. Using separate, low intensity (<10^13 W/cm2) nanosecond laser pulses, focused onto the front surface of the target foil prior to the arrival of the high intensity pulse, it is demonstrated that the proton beam profile can be actively manipulated. In particular, results obtained with an annular intensity distribution at the focus of the low intensity beam are presented, showing smooth proton beams with a sharp circular boundary at all energies, which represents a significant improvement in the beam quality compared to irradiation with the picosecond beam alone.
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| 9. |
- Carroll, D. C., et al.
(author)
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A modified Thomson parabola spectrometer for high resolution multi-MeV ion measurements-Application to laser-driven ion acceleration
- 2010
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In: Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. - : Elsevier BV. - 0168-9002. ; 620:1, s. 23-27
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Conference paper (peer-reviewed)abstract
- A novel Thomson parabola ion spectrometer design is presented, in which a gradient electric field configuration is employed to enable a compact design capable of high resolution measurements of ion energy and charge-to-mass ratio. Practical issues relating to the use of the spectrometer for measurement of ion acceleration in high-power laser-plasma experiments are discussed. Example experimental results for ion acceleration from petawatt-class laser interactions with thin gold target foils are presented. (C) 2010 Elsevier B.V. All rights reserved.
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| 10. |
- Carroll, David C., et al.
(author)
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Dynamic control and enhancement of laser-accelerated protons using multiple laser pulses
- 2009
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In: Comptes Rendus. Physique. - : Elsevier BV. - 1631-0705. ; 10:2-3, s. 188-196
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Journal article (peer-reviewed)abstract
- The use of schemes involving multiple laser pulses to enhance and control the properties of beams of protons accelerated in ultra-intense laser irradiation of planar foil targets is discussed. Specifically, the schemes include the use of a second laser pulse to produce and control preplasma expansion of the target to enhance energy coupling to the proton beam; the use of a second laser pulse to drive shock deformation of the target to change the direction of the proton beam; and a scheme involving dual high intensity laser pulses to change the properties of the sheath field, with the aim of modifying the proton energy spectrum. An overview of our recent experimental and theoretical results is given. The overall aim of this work is to determine the extent to which the properties of the sheath-accelerated proton beam can be optically controlled, to enable beam delivery at high repetition rates. To cite this article: D.C. Carroll et al., C. R. Physique 10 (2009). (C) 2009 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
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