| 1. |
- Arghand, Taha, et al.
(author)
-
An experimental investigation of the flow and comfort parameters for under-floor, confluent jets and mixing ventilation systems in an open-plan office
- 2015
-
In: Building and Environment. - : Elsevier BV. - 0360-1323 .- 1873-684X. ; 92, s. 48-60
-
Journal article (peer-reviewed)abstract
- There is a new trend to convert the workplaces from individual office rooms to open offices for motivating money saving and better communication. With such a shift the ability of existing ventilation systems in meeting the new requirements is a challenging question for researchers. The available options could have an impact on workers' health in terms of providing acceptable levels of thermalcomfort and indoor air quality. Thus, this experimental investigation focuses on the performances of three different air distribution systems in an open-plan office space. The investigated systems were: mixing ventilation with ceiling-mounted inlets, confluent jets ventilation and underfloor air distribution with straight and curved vanes. Although this represents a small part of our more extensiveexperimental investigation, the results show that all the purposed stratified ventilation systems (CJV and UFAD) were more or less behaving as mixing systems with some tendency for displacement effects. Nevertheless, it is known that the mixing systems have a stable flow pattern but has the disadvantage of mixing contaminated air with the fresh supplied air which may produce lower performance and in worst cases occupants' illness. For the open-plan office we studied here, it will be shown that the new systems are capable of performing better than the conventional mixing systems. As expected, the higher air exchange efficiency in combination with lower local mean age of air for corner-mounted CJV and floor-mounted UFAD grills systems indicates that these systems are suitable for open-plan offices and are to be favored over conventional mixing systems.
|
|
| 2. |
- Broström, Tor, et al.
(author)
-
Convective heating in a medieval church : Effects of air-to-air heat pumps on air movements, particle deposition and temperature distribution
- 2009
-
In: Proceedings of the 11th International Conference on Air Distribution in Rooms (Roomvent) 2009, Busan, Korea.
-
Conference paper (peer-reviewed)abstract
- In Europe many historic buildings use direct electric heating. Air-to-air heat pumps are an interesting alternative, in particular for conservation heating. However, the convective heating may accelerate soiling of walls and artefacts by increasing the velocity and turbulence. The objective of the present paper is to discuss the general problem, the methodology for studying air motions and temperature distribution, and to present the results from a case study where air-to-air heat pumps and bench heaters were used for heating in a medieval church. The temperatures, velocities and humidity in the church have been measured for four different heating modes. The present study does not indicate any major disadvantages of using heat pumps for background heating in stone churches of the studied kind. More detailed long term studies are needed to ascertain the effects over time.
|
|
| 3. |
|
|
| 4. |
- Forsberg, Ann-Kristin, et al.
(author)
-
An augmented-reality approach to co-located visual exploration of indoor climate data in real rooms
- 2005
-
In: Indoor Air 2005: Proceedings of the 10th International Conference on Indoor Air Quality and Climate. - 9787894948304 ; , s. 2860-2860
-
Conference paper (other academic/artistic)abstract
- We live in two spaces, the visible space and the non-visible but otherwise sensed space. Both spaces must satisfy our needs and there is a relation between them. If parts of the room are too cold this will lead to a restriction of the use of the room. We cannot endure draft for any longer time. Draft caused by a ventilation supply frequently leads to blockage of the supply device, which in turn gives rise to a reduction of the ventilation rate. The final result may be a deterioration of the air quality. Therefore, to be able to guarantee the air quality it is necessary to make the invisible thermal climate visible. In this paper a novel method based on Augmented Reality for presenting die thermal climate is presented and discussed. The data, e.g. temperatures and velocities, are shown on a lightweight display. Several people can walk around in a real room and see on a screen where the hot and/or cold spots may appear. Different ventilation solutions could in that way be compared in a dialogue between different actors in the building process.
|
|
| 5. |
- Forslund, Maria, 1978, et al.
(author)
-
International evidence-based guideline on assessment and management of PCOS-A Nordic perspective.
- 2024
-
In: Acta obstetricia et gynecologica Scandinavica. - 1600-0412. ; 103:1, s. 7-12
-
Journal article (peer-reviewed)abstract
- Polycystic ovary syndrome (PCOS) affects about 12% of women of reproductive age. In 2018, the first evidence-based guideline on assessment and management of PCOS was published, and an updated extended guideline was released in August 2023. These guidelines followed best practice and are endorsed by 39 organizations worldwide, making them the most robust source of evidence to guide clinical practice. In the 2023 guideline, diagnostic criteria have been further refined as polycystic ovary morphology can now be assessed with gynecological ultrasound or elevated anti-Müllerian hormone levels. A healthy lifestyle should be at the focus of care for all women with PCOS; however, with no specific diet or physical exercise recommended. The latest evidence on medical treatments and fertility management are reviewed, including special considerations regarding long-term follow-up of metabolic and psychiatric comorbidities and pregnancy in women with PCOS. Here we summarize the recommendations from a Nordic perspective.
|
|
| 6. |
- Hayati, Abolfazl, 1985-, et al.
(author)
-
Evaluation of two air infiltration models on a church
- 2013
-
In: Conference proceedings: Cultural heritage preservation – 3rd European Workshop on Cultural Heritage Preservation. - 9788888307268 ; , s. 47-53
-
Conference paper (peer-reviewed)abstract
- Air infiltration in ancient churches and other historical and monumental buildings is of great importance considering moisture transfer, energy consumption, thermal comfort and indoor surface soiling. Two of the most established models for simulatingand predicting air infiltration in buildings are the Lawrence BerkeleyLaboratory (LBL) model and the Alberta air Infiltration Model (AIM-2). The applicability of these models in superimposing wind and buoyancy driven infiltration in large single zone buildings such as churches are evaluated in this study by comparing model predictions with field measurements in a 19thcentury stone church. Both tested air infiltration models yielded significant positive correlations between measured and predicted data, and it is concludedthat the AIM-2 model works better than the LBL model for the studied church. Both models tend however to over-predict the air infiltration rate significantly. The over‑predictions were larger in cases with high wind speed and it seems that the models are more fragile in wind dominating conditions. Inclusion of crawl space coefficients in the AIM-2 model improved however the predictions, especially at high wind speeds. It seems that models of the tested kind can be useful in predicting air infiltration in churches and similar buildings, but that some empirically attained model coefficients might need some adjustment to suit this kind of buildings better.
|
|
| 7. |
|
|
| 8. |
- Kabanshi, Alan, et al.
(author)
-
Plenum airflow distribution and its influence on the performance of a diffuse ceiling ventilation
- 2022
-
In: E3S Web Conf. Volume 356, 2022 The 16<sup>th</sup> ROOMVENT Conference (ROOMVENT 2022). - Xian : EDP Sciences.
-
Conference paper (peer-reviewed)abstract
- Implementation of diffuse ceiling ventilation (DCV) is slowly gaining momentum and applications in building ventilation have taken off with countries like Denmark, Finland and Netherlands taking the lead in Europe. However, DCV is yet to gain a foothold in Sweden and so not many installations are known, and their performance in relation to Swedish building practice is not yet established. A school in southern Sweden was subsequently renovated and two classrooms were equipped with a sound-absorbent suspended ceiling compatible with DCV. DCV has possible benefits for educational environments including improved thermal comfort as well as lower costs and noise levels. However, it is currently still unknown how supply conditions in the plenum affect the diffusion of air and resulting conditions within the room. To assess airflow characteristics and whether these influence flow conditions in the classroom, we investigated and compared the performance of DCV with two different supply conditions in the plenum. Air speeds and temperature distribution measurements in the plenum and classroom were performed with constant temperature anemometers and thermocouples respectively. The general observation from this study and the system setup herein is that airflow and temperature characteristics in the classroom were independent of the airflow conditions in the plenum. Further investigations in a controlled climate chamber are recommended to investigate and optimise system performance in accordance with Swedish building practice.
|
|
| 9. |
- Knevel, R., et al.
(author)
-
A genetic variant in granzyme B is associated with progression of joint destruction in rheumatoid arthritis
- 2013
-
In: Arthritis and Rheumatism. - : Wiley. - 1529-0131 .- 0004-3591. ; 65:3, s. 582-589
-
Journal article (peer-reviewed)abstract
- Objective Genetic factors account for an estimated 4558% of the variance in joint destruction in rheumatoid arthritis (RA). The serine proteinase granzyme B induces target cell apoptosis, and several in vitro studies suggest that granzyme B is involved in apoptosis of chondrocytes. Serum levels of granzyme B are increased in RA and are also associated with radiographic erosions. The aim of this study was to investigate GZMB as a candidate gene accounting for the severity of joint destruction in RA. Methods A total of 1,418 patients with 4,885 radiograph sets of the hands and feet from 4 independent cohorts were studied. First, explorative analyses were performed in 600 RA patients in the Leiden Early Arthritis Clinic cohort. Fifteen single-nucleotide polymorphisms (SNPs) tagging GZMB were tested. Significantly associated SNPs were genotyped in data sets representing patients from the Groningen, Sheffield, and Lund cohorts. In each data set, the relative increase in the annual rate of progression in the presence of a genotype was assessed. Data were summarized in a meta-analysis. The association of GZMB with the RNA expression level of the GZMB genomic region was tested by mapping expression quantitative trait loci (QTLs) on 1,469 whole blood samples. Results SNP rs8192916 was significantly associated with the rate of joint destruction in the first cohort and in the meta-analysis of all data sets. Patients homozygous for the minor allele of rs8192916 had a higher rate of joint destruction per year compared with other patients (P = 7.8 x 104). Expression QTL of GZMB identified higher expression in the presence of the minor allele of rs8192916 (P = 2.27 x 105). Conclusion SNP rs8192916 located in GZMB is associated with the progression of joint destruction in RA as well as with RNA expression in whole blood.
|
|
| 10. |
- Knevel, R., et al.
(author)
-
Genetic variants in IL15 associate with progression of joint destruction in rheumatoid arthritis: a multicohort study
- 2012
-
In: Annals of the Rheumatic Diseases. - : BMJ. - 1468-2060 .- 0003-4967. ; 71:10, s. 1651-1657
-
Journal article (peer-reviewed)abstract
- Background Interleukin (IL)-15 levels are increased in serum, synovium and bone marrow of patients with rheumatoid arthritis (RA). IL-15 influences both the innate and the adaptive immune response; its major role is activation and proliferation of T cells. There are also emerging data that IL-15 affects osteoclastogenesis. The authors investigated the association of genetic variants in IL15 with the rate of joint destruction in RA. Method 1418 patients with 4885 x-ray sets of both hands and feet of four independent data sets were studied. First, explorative analyses were performed on 600 patients with early RA enrolled in the Leiden Early Arthritis Clinic. Twenty-five single-nucleotide polymorphisms (SNPs) tagging IL-15 were tested. Second, SNPs with significant associations in the explorative phase were genotyped in data sets from Groningen, Sheffield and Lund. In each data set, the relative increase of the progression rate per year in the presence of a genotype was assessed. Subsequently, data were summarised in an inverse weighting meta-analysis. Results Five SNPs were significantly associated with rate of joint destruction in phase 1 and typed in the other data sets. Patients homozygous for rs7667746, rs7665842, rs2322182, rs6821171 and rs4371699 had respectively 0.94-, 1.04-, 1.09-, 1.09- and 1.09- fold rate of joint destruction compared to other patients (p = 4.0x10(-6), p = 3.8x10(-4), p = 5.0x10(-3), p = 5.0x10(-3) and p = 9.4x10(-3)). Discussion Independent replication was not obtained, possibly due to insufficient power. Meta-analyses of all data sets combined resulted in significant results for four SNPs (rs7667746, p < 0.001; rs7665842, p < 0.001; rs4371699, p = 0.01; rs6821171, p = 0.01). These SNPs were also significant after correction for multiple testing. Conclusion Genetic variants in IL-15 are associated with progression of joint destruction in RA.
|
|
