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- Kehoe, Laura, et al.
(author)
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Make EU trade with Brazil sustainable
- 2019
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In: Science. - : American Association for the Advancement of Science (AAAS). - 0036-8075 .- 1095-9203. ; 364:6438, s. 341-
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Journal article (other academic/artistic)
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| 5. |
- Abbondanno, U, et al.
(author)
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The data acquisition system of the neutron time-of-flight facility n_TOF at CERN
- 2005
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In: Nuclear Instruments and Methods in Physics Research Section A. - : Elsevier BV. - 0168-9002 .- 1872-9576. ; 538:1-3, s. 692-702
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Journal article (peer-reviewed)abstract
- The n_TOF facility at CERN has been designed for the measurement of neutron capture, fission and (n, xn) cross-sections with high accuracy. This requires a flexible and-due to the high instantaneous neutron flux-almost dead time free data acquisition system. A scalable and versatile data solution has been designed based on 8-bit flash-ADCs with sampling rates up to 2 GHz and 8 Mbyte memory buffer. The software is written in C and C++ and is running on PCs equipped with RedHat Linux.
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| 6. |
- Díaz-Cortes, J., et al.
(author)
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Systematic reduction of the proton-removal cross section in neutron-rich medium-mass nuclei
- 2020
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In: Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics. - : Elsevier BV. - 0370-2693. ; 811
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Journal article (peer-reviewed)abstract
- Single-neutron and single-proton removal cross sections have been measured for medium-mass neutron-rich nuclei around Z=50 and energies around 1000A MeV using the FRagment Separator (FRS) at GSI. The measured cross sections confirm the relative low values of the proton-removal cross sections, observed since a long time ago and not yet understood. Model calculations considering the knock-out process together with initial- and final-state interactions describe the measured neutron-removal cross sections. Proton-removal cross sections are, however, significantly over-predicted by the same calculations. The observed difference can be explained to a large extent by the knock-out of short-range correlated nucleons from dominant neutron-proton pairs in neutron-rich nuclei.
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| 7. |
- Paradela, C., et al.
(author)
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High accuracy 235U(n,f) data in the resonance energy region
- 2016
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In: EPJ Web of Conferences. - : EDP Sciences. - 2100-014X.
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Conference paper (peer-reviewed)abstract
- The U-235 neutron-induced cross section is widely used as reference cross section for measuring other fission cross sections, but in the resonance region it is not considered as an IAEA standard because of the scarce experimental data covering the full region. In this work, we deal with a new analysis of the experimental data obtained with a detection setup based on parallel plate ionization chambers (PPACs) at the CERN n_TOF facility in the range from 1 eV to 10 keV. The relative cross section has been normalised to the IAEA value in the region between 7.8 and 11 eV, which is claimed as well-known. Comparison with the ENDF/B-VII evaluation and the IAEA reference file from 100 eV to 10 keV are provided.
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| 8. |
- Perez-Loureiro, D., et al.
(author)
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Neutron-rich fragments produced by in-flight fission of U 238
- 2019
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In: Physical Review C. - 2469-9993 .- 2469-9985. ; 99:5
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Journal article (peer-reviewed)abstract
- The production cross sections of neutron-rich fission residues in reactions induced by U238 projectiles at 950A MeV impinging on Pb and Be targets are investigated at the Fragment Separator at GSI. These two targets allow us to investigate fission processes induced by two reaction mechanisms, Coulomb and nuclear excitations, and to study the role of these mechanisms in the neutron excess of the final fragments.
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| 9. |
- Forquin, P., et al.
(author)
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Investigation of the Mechanical Behaviour of Lingulid Sandstone Emphasising the Influence from Pre-Existing Structural Defects, Part 1 : Model Identification Based on Static Experiments
- 2022
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In: Applied Sciences. - : MDPI AG. - 2076-3417. ; 12:21, s. 10806-
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Journal article (peer-reviewed)abstract
- A constitutive model able to describe both tensile damage and plastic deformation under confinement is a prerequisite to numerically simulate the behaviour of sandstone rock under an impact loading induced in a percussive drilling process. Therefore, model identification under both tensile and high confinement states is needed. In the present work, an experimental investigation was carried out in order to determine the mechanical properties of a sandstone rock for the purpose of advanced constitutive model identification. Different testing methods were used in quasistatic and dynamic loading regimes. This first part of the study is dedicated to static experiments, whereby three-point bend tests were first performed to evaluate the quasistatic tensile strength of the rock and its distribution by employing the Weibull statistics. Secondly, direct compression tests were conducted to evaluate the stiffness and strength in an unconfined condition. Afterwards, quasioedometric compression (QOC) tests were carried out in order to obtain the deviatoric and volumetric behaviours of the material as a function of the hydrostatic pressure (up to 375 MPa). In these QOC tests, the metallic confinement cell was instrumented with strain gauges to deduce the state of the stress and strain within the sample. A linear volumetric response along with a continuous increase of strength with the level of hydrostatic pressure was observed. This experimental work points out that, under unconfined loading (three-point bending and uniaxial compression), pre-existing structural defects play a major role leading to a highly scattered behaviour in terms of sample stiffness and ultimate applied load. On the other hand, under high confinement levels (QOC tests), beyond the nonlinear response of the curve foot, the influence from structural defects was observed to be small.
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| 10. |
- Lauc, Gordan, et al.
(author)
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Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers
- 2013
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In: PLOS Genetics. - : Public Library of Science (PLoS). - 1553-7390 .- 1553-7404. ; 9:1, s. e1003225-
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Journal article (peer-reviewed)abstract
- Glycosylation of immunoglobulin G (IgG) influences IgG effector function by modulating binding to Fc receptors. To identify genetic loci associated with IgG glycosylation, we quantitated N-linked IgG glycans using two approaches. After isolating IgG from human plasma, we performed 77 quantitative measurements of N-glycosylation using ultra-performance liquid chromatography (UPLC) in 2,247 individuals from four European discovery populations. In parallel, we measured IgG N-glycans using MALDI-TOF mass spectrometry (MS) in a replication cohort of 1,848 Europeans. Meta-analysis of genome-wide association study (GWAS) results identified 9 genome-wide significant loci (P<2.27x10(-9)) in the discovery analysis and two of the same loci (B4GALT1 and MGAT3) in the replication cohort. Four loci contained genes encoding glycosyltransferases (ST6GAL1, B4GALT1, FUT8, and MGAT3), while the remaining 5 contained genes that have not been previously implicated in protein glycosylation (IKZF1, IL6ST-ANKRD55, ABCF2-SMARCD3, SUV420H1, and SMARCB1-DERL3). However, most of them have been strongly associated with autoimmune and inflammatory conditions (e. g., systemic lupus erythematosus, rheumatoid arthritis, ulcerative colitis, Crohn's disease, diabetes type 1, multiple sclerosis, Graves' disease, celiac disease, nodular sclerosis) and/or haematological cancers (acute lymphoblastic leukaemia, Hodgkin lymphoma, and multiple myeloma). Follow-up functional experiments in haplodeficient Ikzf1 knock-out mice showed the same general pattern of changes in IgG glycosylation as identified in the meta-analysis. As IKZF1 was associated with multiple IgG N-glycan traits, we explored biomarker potential of affected N-glycans in 101 cases with SLE and 183 matched controls and demonstrated substantial discriminative power in a ROC-curve analysis (area under the curve=0.842). Our study shows that it is possible to identify new loci that control glycosylation of a single plasma protein using GWAS. The results may also provide an explanation for the reported pleiotropy and antagonistic effects of loci involved in autoimmune diseases and haematological cancer.
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