| 1. |
- Cronqvist, Marie, et al.
(författare)
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Inledning
- 2014
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Ingår i: Mediehistoriska vändningar. - 1654-6601. - 9789188468321 ; 25
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Cronqvist, Marie, et al.
(författare)
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Inledning
- 2014
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Ingår i: Återkopplingar. - 1654-6601. - 9789198196122 - 9789198196702 ; 28, s. 9-28
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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| 3. |
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| 4. |
- Lundell, Patrik, et al.
(författare)
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Historiska vägar i offentlighetsteorin
- 2014
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Ingår i: Mediehistoriska vändningar. - Lund : Lunds universitet. - 1654-6601. - 9789188468321 ; 25
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Bokkapitel (refereegranskat)
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| 5. |
- Moberg, Christina, et al.
(författare)
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De unga gör helt rätt när de stämmer staten
- 2022
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Ingår i: Aftonbladet. - 1103-9000.
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Tidskriftsartikel (populärvet., debatt m.m.)abstract
- 1 620 forskare och lärare i forskarvärlden: Vi ställer oss bakom Auroras klimatkrav
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| 6. |
- Bjursten, Sara, et al.
(författare)
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Concentrations of S100B and neurofilament light chain in blood as biomarkers for checkpoint inhibitor-induced CNS inflammation
- 2024
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Ingår i: EBioMedicine. - 2352-3964. ; 100
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Tidskriftsartikel (refereegranskat)abstract
- Background Cancer treatment with immune checkpoint inhibition (ICI) can cause immune -related adverse events in the central nervous system (CNS irAE). There are no blood biomarkers to detect CNS irAE. We investigated if concentrations of S100 -calcium -binding protein B (S100B) and neurofilament light chain (NfL) in blood can be used as biomarkers for CNS irAE and assessed the incidence of CNS irAE in a cohort of ICI -treated patients. Methods In this single -centre, retrospective cohort study, we examined medical records and laboratory data of 197 consecutive patients treated with combined CTLA-4 and PD -1 inhibition (ipilimumab; ipi + nivolumab; nivo) for metastatic melanoma or renal cell carcinoma. CNS irAE was diagnosed using established criteria. Concentrations of S100B and NfL in blood were measured in patients with CNS irAE and in 84 patients without CNS irAE. Findings Nine of 197 patients (4.6%) fulfilled criteria for CNS irAE. S100B and NfL in blood increased during CNS inflammation and normalized during immunosuppression. CNS irAE was detected with a sensitivity of 100% (S100B) and 79% (NfL) and a specificity of 89% (S100B) and 74% (NfL). Patients with CNS irAE had simultaneous increased concentration of C -reactive protein (CRP) (9/9) and alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) in blood (8/9). Interpretation Analysis of S100B, NfL and CRP in blood facilitates the diagnosis of CNS irAE. CNS irAE may be more common than previously reported. There may be shared immune mechanisms between CNS and hepatitis irAE.
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| 7. |
- Carlsson Tedgren, Åsa, et al.
(författare)
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Experience from long-term monitoring of RAKR ratios in Ir-192 brachytherapy
- 2008
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Ingår i: Radiotherapy and Oncology. - : Elsevier BV. - 0167-8140 .- 1879-0887. ; 89:2, s. 217-221
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Tidskriftsartikel (refereegranskat)abstract
- Background: Ratios of values of brachytherapy source strengths, as measured by hospitals and vendors, comprise constant differences as, e.g., systematic errors in ion chamber calibration factors and measurement setup. Such ratios therefore have the potential to reveal the systematic changes in routines or calibration services at either the hospital or the vendor laboratory, which could otherwise be hidden by the uncertainty in the source strength values. Methods: The RAKR of each new source in 13 afterloading units at five hospitals were measured by well-type ion chambers and compared to values for the same source stated on vendor certificates. Results: Differences from unity in the ratios of RAKR values determined by hospitals and vendors are most often small and stable around their mean values to within +/- 11.5%. Larger deviations are rare but occur. A decreasing ratio, seen at two hospitals for the same source, was useful in detecting an erroneous pressure gauge at the vendors site. Conclusions: Establishing a mean ratio of RAKR values, as measured at the hospital and supplied on the vendor certificate, and monitoring this as a function of time are an easy way for the early detection of problems with equipment or routines at either the hospital or the vendor site.
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| 8. |
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| 9. |
- Cronqvist, Marie, et al.
(författare)
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Inledning
- 2014
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Ingår i: Återkopplingar. - Lund : Lunds universitet. - 9789198196122 ; , s. 9-28
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Bokkapitel (refereegranskat)
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| 10. |
- Cronqvist, Marie, et al.
(författare)
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Inledning
- 2014
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Ingår i: Mediehistoriska vändningar. - Lund : Lunds universitet. - 9789188468321 ; , s. 5-18
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Bokkapitel (övrigt vetenskapligt/konstnärligt)
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