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1.
  • Cassel, Björn, et al. (author)
  • Deflections of an implant-supported cantilever beam subjected to vertically directed loads : in vitro measurements in three dimensions using an optoelectronic method. I. Experimental set-up.
  • 2011
  • In: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 22:3, s. 275-281
  • Journal article (peer-reviewed)abstract
    • Aim: The aim of this in vitro study was to develop and test an experimental set-up consisting of a video camera and computer-based optoelectronic motion analysis system, synchronized with a loading device, for studying load-dependent deflections in three dimensions of single implant-supported cantilever beams.Material and methods: One Brånemark System implant was tightly screwed into a steel plate so that the entire implant became submerged. An abutment was attached to the implant and a cast 22-mm-long cantilever gold alloy beam incorporating a prefabricated gold cylinder was attached to the abutment with a prosthetic gold screw. A force transducer was glued on the upper surface of the beam end with its centre 19.4 mm from the centre of the implant abutment gold cylinder unit to register the applied load. A specially designed loading device was used to apply increasing vertical loads of the beam end via the transducer. The motion analysis system was synchronized with the transducer to enable measurements of three-dimensional positional changes of the beam end related to known loads.Results: Vertical loads from 15.7 to 40.4 N were applied resulting in vertical positional changes of the beam end ranging from 40.8 to 225.2 μm (z-axis). The corresponding horizontal changes perpendicular to the long axis of the beam (y-axis) due to counterclockwise horizontal rotation of the beam around the abutment- and prosthetic cylinder threads varied from 7.4 to 77.4 μm. This rotation changed the position of the beam end from 11.9 to 49.3 μm along the x-axis of the coordinate system toward the supporting implant.Conclusion: It was possible to arrange an experimental set-up for optoelectronic 3-D measurements within such a limited measurement volume that would permit satisfactory registrations of small load-dependent deflections of the prosthetic beam and implant components.
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2.
  • Cassel, Björn, et al. (author)
  • Deflections of an implant-supported cantilever beam subjected to vertically directed loads : In vitro measurements in three dimensions using an optoelectronic method. II Analysis of methodological errors.
  • 2010
  • In: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 22:6, s. 645-650
  • Journal article (peer-reviewed)abstract
    • Aim: The aim of this study was to evaluate the accuracy, i.e. trueness (validity) and precision (repeatability) for load-dependent deflections in three dimensions of an implant-supported cantilever beam obtained with an optoelectronic motion analysis system compared with a well-known reference method.Materials and methods: A cantilever beam with a length of 22 mm (roughly corresponding to the width of two premolars) was screw-connected to an implant–abutment unit stiffly anchored in a steel plate. The positional changes of beam-end were measured when the beam-end step by step was subjected to four loads, 15.5–40.1 N. This measurement procedure was repeated to comprise six consecutive measurements. The trueness of the method was estimated by comparing the data obtained for vertical deflections with those from a reference method where a hydraulic test system was used to measure the load-deflection ratios of the same beam when subjected to the four mentioned vertical loads.Results: All applied transducer-mediated loads had accuracies (truenesses and repeatabilities below 0.05%). Also, the trueness and precision of the reference method, regarding both movements (deflections) of tested objects and magnitude of applied loads, were tested and found to be high, not exceeding 0.5%.The optoelectronic method however underestimated the smallest vertical deflections for the cantilever beam when compared with the data obtained from the reference method. The underestimation was 26.4%, 15.5% and 8.6% for loads 15.5, 26.6 and 32.6 N, respectively, while there was a slight overestimation of 1.2% for 40.1 N. The precision for the optoelectronic method was found to be for z-axis 1.8 μm, y-axis 3.8 μm and x-axis 1.9 μm.Conclusion: It can be concluded that the trueness (validity) for the optoelectronic method is very high for deflections above 143 μm. The precision (repeatability) of the optoelectronic method was found to be very high.
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3.
  • Cassel, Björn, et al. (author)
  • The influence of stiffness of implant-abutment connection on load-deflection ratios of a screw-retained stiff cantilever beam. 3-D measurements in vitro
  • 2013
  • In: Clinical Oral Implants Research. - : Wiley. - 0905-7161 .- 1600-0501. ; 24:11, s. 1251-1256
  • Journal article (peer-reviewed)abstract
    • Aim: The purpose of this in vitro study was to investigate the influence of degree of stiffness of implant-abutment connection of a Brånemark implant system on load- deflection ratios in three dimensions of the beam-end of a screw-retained stiff cantilever beam when subjected to vertically directed loads.Material and methods: Two different implant-abutment connections were tested; welded and screw-retained. One of the abutments (EsthetiCone 2.0; Nobel Biocare AB) was screwed with a torque force of 20 N cm and then laser welded around its entire periphery to one of two Brånemark implants (welded unit). This unit and the other implant were tightly screwed into each of two pre-threaded holes in a steel plate so that the implants became submerged in the plate. The remaining abutment was thereafter screwed to its implant with a torque force of 20 N cm (screw-retained unit). A cantilevered gold beam of 6 mm height and width comprising a gold cylinder (Nobel Biocare AB) was attached to each abutment with a slotted, flat headed, prosthetic gold screw (torque force 10 N cm). A force transducer, synchronized with a 3-D motion analysis system, was glued on the upper surface of each beam-end 19.4 mm from the implant, to register the loads transferred from a specially built loading device. The beam-ends were stepwise subjected to vertically directed loads from 14.9 to 40.3 N and the vertical and horizontal deflections of the beam-ends were registered with the 3-D motion analysis system.Results: For load 14.9–40.3 N the vertical (z-axis) deflections of the beam-end were for the welded implant-abutment connection reduced with 18–46% compared with the screw-retained unit. After maximal loading (40.3 N) the horizontal counter-clockwise rotation of the beam around the screw joints (y-axis rotations) was reduced with 61% for the welded connection. The horizontal movements of the beam-end along the x-axis (x-axis deflections) were reduced with 49% at maximal loading.Conclusion: It was concluded that increased implant-abutment stiffness will substantially reduce both vertical and horizontal deflections of a screw-retained stiff cantilever beam subjected to vertically directed loads.
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4.
  • Lundgren, Anna Karin, et al. (author)
  • An experimental rabbit model for jaw-bone healing.
  • 1997
  • In: International journal of oral and maxillofacial surgery. - : Elsevier BV. - 0901-5027. ; 26:6, s. 461-4
  • Journal article (peer-reviewed)abstract
    • The purpose of this investigation was to study the structural and topographical bone anatomy of the right and left edentulous areas between the incisors and molars in the rabbit maxilla with regard to the symmetry of the bone, and to assess the degree of spontaneous healing of surgical defects. Anatomical and radiographic examinations together with analysis of serial histological ground sections in ten rabbits disclosed no statistically significant differences between the two sides regarding the different bone-tissue structures, i.e. they exhibit a sufficient degree of symmetry to serve as a useful bilateral test-control model. Surgical defects were made on one side of the jaw (test side) in a group of eight rabbits. This resulted in an average loss of 17% of the total bone volume after a healing period of four weeks as compared to the untreated control side. It was concluded that surgically-created defects do not show completely spontaneous healing. From a histological section of the test side, it was possible to redraw the original bone contour by interpolation between unaffected areas of bone, coronal and apical to the defect. This means that the test side of this model can also serve as its own control with regard to the amount of regenerated tissue, given that there is unaffected bone, coronal and apical to the defect.
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5.
  • Lundgren, Anna Karin, et al. (author)
  • Augmentation of skull bone using a bioresorbable barrier supported by autologous bone grafts. An intra-individual study in the rabbit.
  • 1997
  • In: Clinical oral implants research. - : Wiley. - 0905-7161. ; 8:2, s. 90-5
  • Journal article (peer-reviewed)abstract
    • The aim of this experimental investigation was to compare the effect of using autologous particulate bone grafts with and without a bioresorbable barrier covering for augmentation of the rabbit skull bone. For this purpose, bilateral, circular, 8 mm wide and 1 mm deep skull bone defects were prepared and overfilled with particulate bone grafts. The grafts placed in the test sites were covered with a bioresorbable barrier (Guidor Matrix Barrier). The grafts placed in the control sites were covered only by the repositioned, cutaneous flap. 12 weeks later, the animals were sacrificed, the experimental sites were defleshed and the height and volume of the augmented bone in the test and control sites were measured clinically. Histologically, morphometrical measurements of the bone tissue were performed in decalcified vertical cross-sections of the experimental sites. Statistically significant differences were found in favour of the coverage of the bone graft particles with the barrier, both with respect to the height and the volume of the augmented bone.
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6.
  • Lundgren, Anna Karin, et al. (author)
  • Bone augmentation at titanium implants using autologous bone grafts and a bioresorbable barrier. An experimental study in the rabbit tibia.
  • 1997
  • In: Clinical oral implants research. - : Wiley. - 0905-7161. ; 8:2, s. 82-9
  • Journal article (peer-reviewed)abstract
    • The aim of the present investigation was to compare the effect of using autologous bone particles covered with a bioresorbable matrix barrier with the use of bone particles alone on bone augmentation at titanium implants installed in the rabbit tibia. Two Brånemark System implants, one in each tibia, were inserted in each of 9 rabbits in such a way that 5 threads were not covered with bone. Autologous bone particles were harvested from the skull and placed over the exposed implant surfaces on each tibia. The bone graft on one tibia was covered with a Guidor Matrix Barrier, while the bone graft on the other tibia served as a control. After a healing period of 12 weeks, the animals were sacrificed and specimens taken for histomorphometrical analyses. The analyses showed that a significantly larger volume of augmented bone tissue had formed at the test sites. There were, however, no differences in the amount of mineralized bone. In fact, the difference in tissue volume was due to an increased amount of bone marrow at the test sites. The degree of mineralized bone to implant contact as well as the degree of mineralized bone within the threads at the test implants were similar to that at the controls. In conclusion, it was found that the coverage of particulate autologous bone grafts with a bioresorbable barrier resulted in a larger volume of augmented bone than the use of bone grafts not covered with a barrier.
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7.
  • Lundgren, Anna Karin, et al. (author)
  • Guided jaw-bone regeneration using an experimental rabbit model.
  • 1998
  • In: International journal of oral and maxillofacial surgery. - : Elsevier BV. - 0901-5027. ; 27:2, s. 135-40
  • Journal article (peer-reviewed)abstract
    • The aims of this study were to evaluate the space-maintaining capacity of two biocompatible barrier materials and to assess the effect of barrier occlusiveness on the amount of regenerated bone. Defects were prepared in the edentulous area on both sides of the maxillas in 22 rabbits. The rabbits were divided into three groups. Gore-Tex augmentation material (GTAM) (ePTFE)-barriers were placed to cover the experimental defects and compared with totally occlusive or perforated titanium foils and uncovered control defects respectively. After four weeks of healing, histological analyses and morphometrical measurements demonstrated that the amount of regenerated bone tissue was about the same underneath the collapsed GTAM-barriers as in the controls. The highest degree of regeneration was obtained in defects underneath the titanium foils, particularly if they were perforated, whether or not they were covered by GTAM-barriers. It was concluded that the space-maintaining properties of a barrier may be at least as important as barrier occlusiveness when regenerating bone defects.
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8.
  • Lundgren, Dan, et al. (author)
  • Augmentation of intramembraneous bone beyond the skeletal envelope using an occlusive titanium barrier. An experimental study in the rabbit.
  • 1995
  • In: Clinical oral implants research. - : Wiley. - 0905-7161. ; 6:2, s. 67-72
  • Journal article (peer-reviewed)abstract
    • The aim of this investigation was to evaluate whether augmentation of intramembraneous bone beyond the skeletal envelope can be predictably achieved by placing a completely occlusive barrier on the skull bone of rabbits, hereby creating a secluded space with bone tissue being the only adjoining tissue. The experiment was carried out in 3 New Zealand white rabbits. In each animal, a midline incision was made down to the bone surface of the skull and a skin-periosteal flap was raised to expose the skull bone on both sides of the midline. Two prefabricated titanium domes with an inner diameter of 4.5 mm and an inner height of 3.0 mm were installed on each side. The domes were supplied with a horizontal, peripheral flange and a vertical edge, fitting tightly into a circular slit, prepared by a trephine into the skull bone. This arrangement ensured a stable anchorage of the dome and a reliable peripheral sealing of the space. The skin-periosteal flaps were relocated to cover the domes and sutured. After a healing period of 3 months, the animals were killed and the experimental areas excised and prepared for histological transversal ground sections with each dome in situ. The results demonstrated complete bone fill of all domes, with no signs of ingrowth of other types of tissues, indicating that the use of a barrier with total occlusiveness, sufficient stiffness and stability and reliable peripheral sealing will result in predictable bone augmentation of spaces also beyond the skeletal envelope.
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9.
  • Lundgren, Dan, et al. (author)
  • The effect of mechanical intervention on jaw bone density.
  • 1995
  • In: Clinical oral implants research. - : Wiley. - 0905-7161. ; 6:1, s. 54-9
  • Journal article (peer-reviewed)abstract
    • The aim of this investigation was to test the hypothesis that jaw bone, subjected to mechanical intervention, will heal with increased density compared with conditions before the traumatic insult. The natural edentulous area between the incisor and the first molar on both sides of the maxillary jaw of 8 adult New Zealand white rabbits constituted the experimental model. On the test side, holes were drilled through the cortical plate and into the cancellous bone. No drilling was performed on the contralateral control side. One transversal ground section from each specimen, taken in the centre of and representing both the test and control site, was prepared to ensure that the same sagittal level of the jaw was represented. Morphometric measurements were performed and comprised assessments of the total cross-sectional area of 1) the edentulous part of the jaw, 2) the cortical bone plates and 3) the bone trabeculae and marrow spaces of the cancellous bone. The mechanical intervention resulted in a substantial alteration of the bone tissue morphology, the most conspicuous change being a markedly increased number of bone trabeculae per cancellous bone unit. Thus, the area occupied by bone trabeculae was about twice as large in the test sites compared with the control sites (+103%), whereas the area occupied by bone marrow cavities and cortical bone was significantly smaller. The clinical implications of the findings for potential treatment of fragile bone tissues and bone sites intended for implant insertion are discussed.
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10.
  • Abolfathi, Bela, et al. (author)
  • The Fourteenth Data Release of the Sloan Digital Sky Survey : First Spectroscopic Data from the Extended Baryon Oscillation Spectroscopic Survey and from the Second Phase of the Apache Point Observatory Galactic Evolution Experiment
  • 2018
  • In: Astrophysical Journal Supplement Series. - : IOP Publishing Ltd. - 0067-0049 .- 1538-4365. ; 235:2
  • Journal article (peer-reviewed)abstract
    • The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since 2014 July. This paper describes the second data release from this phase, and the 14th from SDSS overall (making this Data Release Fourteen or DR14). This release makes the data taken by SDSS-IV in its first two years of operation (2014-2016 July) public. Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey; the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data-driven machine-learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from the SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS web site (www.sdss.org) has been updated for this release and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020 and will be followed by SDSS-V.
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