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1.
  • Lundgren, Linnea, et al. (author)
  • Studying Religious Change : Combining Close and Distant Reading in the Field of Sociology of Religion
  • 2022
  • In: Nordic Journal of Religion and Society. - : Scandinavian University Press / Universitetsforlaget AS. - 0809-7291 .- 1890-7008. ; 35:2, s. 111-124
  • Journal article (peer-reviewed)abstract
    • This article explores the possibilities of using digital methods to study religion and religious change in contemporary societies. It argues that despite considerable developments in which analogue data has been converted into digital forms and new digital methods have been developed, these are rarely used in sociology of religion. The article illustrates how new digital methods can complement more traditional qualitative methods and deepen such findings. Using examples from two PhD theses, the article analyses how so-called distant and close reading can be combined in studies. The cases illustrate key points regarding improving validity, representativity and how larger religious changing processes can be studied through large text material. The article concludes by discussing the advantages and disadvantages of using new digital methods and highlighting new possibilities for future studies in the sociology of religion.
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  • Berglund, Sara, et al. (author)
  • Cardiorenal function and survival in in-hospital cardiac arrest : A nationwide study of 22,819 cases
  • 2022
  • In: Resuscitation. - : Elsevier BV. - 0300-9572 .- 1873-1570. ; 172, s. 9-16
  • Journal article (peer-reviewed)abstract
    • Background: We studied the association between cardiorenal function and survival, neurological outcome and trends in survival after in-hospital Methods: We included cases aged 18 years in the Swedish Cardiopulmonary Resuscitation Registry during 2008 to 2020. The CKD-EPI equation was used to calculate estimated glomerular filtration rate (eGFR). A history of heart failure was defined according to contemporary guideline criteria. Logistic regression was used to study survival. Neurological outcome was assessed using cerebral performance category (CPC). Results: We studied 22,819 patients with IHCA. The 30-day survival was 19.3%, 16.6%, 22.5%, 28.8%, 39.3%, 44.8% and 38.4% in cases with eGFR < 15, 15-29, 30-44, 45-59, 60-89, 90-130 and 130-150 ml/min/1.73 m2, respectively. All eGFR levels below and above 90 ml/min/1.73 m2 were associated with increased mortality. Probability of survival at 30 days was 62% lower in cases with eGFR < 15 ml/min/1.73 m2, compared with normal kidney function. At every level of eGFR, presence of heart failure increased mortality markedly; patients without heart failure displayed higher mortality only at eGFR below 30 ml/min/1.73 m2. Among survivors with eGFR < 15 ml/min/1.73 m2, good neurological outcome was noted in 87.2%. Survival increased in most groups over time, but most for those with eGFR < 15 ml/min/1.73 m2, and least for those with normal eGFR. Conclusions: All eGFR levels below and above normal range are associated with increased mortality and this association is modified by the presence of heart failure. Neurological outcome is good in the majority of cases, across kidney function levels and survival is increasing.
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3.
  • Helmersson, Linnea, 1982- (author)
  • Förhandlingar på dansgolvet : en etnologisk studie av lindy hop och polska – två svenska dansscener
  • 2023
  • Doctoral thesis (other academic/artistic)abstract
    • In Sweden today, many different dances are practiced within distinct scenes, which all have their specific characteristics, norms and ideals. This thesis analyses two of these scenes, polska and lindy hop. They share a similar background of revitalisation and revival. The aim of the thesis is to describe and analyse meaning-making processes within the scenes formed around these dance forms. It includes descriptions of historical revival processes but above all analyses of practitioners’ understandings and practices. The main research data consists of interviews with practitioners, and observations on dance events and courses. Theoretically, the study is based on a view of dance and dancing as cultural expressions whose meanings and forms are constantly being created and recreated. The analysis draws on a wide variety of theories and concepts within the humanities and performing arts research. The findings show that beliefs about the past emerge as a framework for practice in the two scenes. In the data, tradition and authenticity are important themes, and there is a shared discourse of preservation. Nevertheless, how important history is for today’s practitioners, and how the past is enacted and what meanings are ascribed to it, differs between and within the scenes. Discourses about the past, as well as processes of authentication, are much more prominent within the lindy hop scene, as compared to the polska scene. This includes aspects such as clothing and the making of and expression of gender. A notable difference between the scenes is that learning to dance is formalised through workshops in the lindy hop scene, whereas it is more informal among polska dancers.The thesis adds to the growing field of studies of revivals of music and dance, and shows how scenes formed around revived dances bear traces of the revival processes while at the same time creating something new in the present. 
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  • Johansson, Patrik, et al. (author)
  • A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma
  • 2020
  • In: Cell Reports. - : Elsevier BV. - 2211-1247. ; 32:2
  • Journal article (peer-reviewed)abstract
    • Glioblastoma (GBM) is a malignant brain tumor with few therapeutic options. The disease presents with a complex spectrum of genomic aberrations, but the pharmacological consequences of these aberrations are partly unknown. Here, we report an integrated pharmacogenomic analysis of 100 patient-derived GBM cell cultures from the human glioma cell culture (HGCC) cohort. Exploring 1,544 drugs, we find that GBM has two main pharmacological subgroups, marked by differential response to proteasome inhibitors and mutually exclusive aberrations in TP53 and CDKN2A/B. We confirm this trend in cell and in xenotransplantation models, and identify both Bcl-2 family inhibitors and p53 activators as potentiators of proteasome inhibitors in GBM cells, We can further predict the responses of individual cell cultures to several existing drug classes, presenting opportunities for drug repurposing and design of stratified trials. Our functionally profiled biobank provides a valuable resource for the discovery of new treatments for GBM.
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  • Lundgren, Anna, et al. (author)
  • Cross-border transport infrastructure planning in the Nordic Region : an introduction
  • 2023
  • Reports (other academic/artistic)abstract
    • Throughout history, transport infrastructure has played a crucial role inindustrialisation, economic growth and regional development and continues to do so. In recent decades, international trade, the growth potential of extended crossborder labour markets and new connections, such as the Öresund bridge (finalised in2000) and the Fehmarn Belt connection between Denmark and Germany (to beopened in 2029), have further increased interest in cross-border transportinfrastructure.This is the first report in the NORDINFRA project, aiming at increasing knowledge ofcross-border transport infrastructure planning in the Nordic Region. The project covers four Nordic countries (Denmark, Finland, Norway and Sweden) and explores institutional and other challenges and opportunities associated with better and more coordinated cross-border transport infrastructure planning.NORDINFRA is a research project financed by the Swedish Transport Administration(Trafikverket) and run by Nordregio and Umeå University. Its research methods consist of literature and document studies as well as interviews with stakeholders.Three Nordic cross-border transport infrastructure case studies have been selected:a new fixed link between Sweden and Denmark, namely the Helsingborg–Helsingör road and rail tunnel; an improved railway connection between Stockholm and Oslo; and the road and ferry connection from Mo i Rana in Norway, via Umeå in Sweden, to Vasa in Finland.This report begins with an overview of the transport infrastructure planning systemsin Denmark, Finland, Norway and Sweden, with a focus on the policy goals, the main actors and their responsibilities within the transport infrastructure planning system, central elements of the planning process, analytical tools and tools for impact analysis.Overall, we find many similarities between the Nordic countries, although there are also important differences. In terms of transport goals, all four countries share important commonalities in that they focus on efficiency, accessibility, sustainability, and safety – although the specific goals are formulated in different ways and with different emphases. We find that, to a large extent, the countries share the same timeframe when it comes to the planning period (Denmark 2021–2035, Finland2021–2032, Norway 2022–2033 and Sweden 2022–2033).These commonalities are positive and can be expected to facilitate the planning of cross-border transport infrastructure objects. The analysis of the countries’ national infrastructure and transportation plans shows that although Nordic cross-border transport is mentioned, the focus is primarily on national transport infrastructure that is not adjacent to a border. In all the countries, planning takes place via step-bystep, formalised processes, including impact assessments. Here, too, the similarities between the countries can be expected to increase the potential for cross-border collaboration.We also find similarities between the Nordic countries studied when it comes to the main actors involved in transport infrastructure planning. At national level, the relevant ministry holds the responsibility for transport infrastructure, along with one or several national authorities in the field. However, one important difference between the Nordic countries is that, according to the Danish and Norwegian public administration models, the national transport authorities have less independence from the transport ministry than the equivalent agencies in Sweden and Finland.In all of the countries, the regional councils are responsible for elaborating a regional development strategy and are frequently involved in public transportation. The municipalities are responsible for local physical planning but may also have other tasks relating to transport infrastructure, such as local roads, local public transport, ports and airports. Looking closer, the division of transport infrastructure tasks between different levels of government varies depending on the country, and there can sometimes be territorial differences within the country, too.However, a general pattern can be observed whereby actors at national level have overall responsibility for the national transport infrastructure system, whereas regional and local actors are endowed with specific tasks and responsibilities within the transport infrastructure system. In order to facilitate cross-border transport infrastructure planning it is important that those actors involved in cross-border transport infrastructure planning have knowledge about these differences between the countries and regions involved to be able to better understand the prerequisites for cross-border infrastructure planning and adapt to the circumstances involved.Although transport infrastructure planning primarily takes place within a national context, also the European Union plays an important role for cross-border transport infrastructure planning. A policy area of great importance is EU transport policy – for example, the Trans-European Transport Network (TEN-T) which aims to link territories across the EU via a core network of corridors, of which the Scandinavian –Mediterranean (Scan-Med) and North Sea–Baltic corridors are most important for the Nordic countries. The EU’s policy for regional development and its Cohesion Policy are both central to cross-border collaboration – not least the Interreg A programmes, which are targeted at cross-border co-operation. Just as the EU regional development policy is connected to measures and financing mechanisms such as the Interreg, the implementation of EU transport policy is facilitated by, e.g.the Connecting Europe Facility (CEF). While EU policies in the fields of regional development and transport support cross-border transport infrastructure planningin the Nordic Region, it is less evident to what extent Nordic co-operation supports cross-border transport infrastructure planning. Even though the national transport authorities are involved in knowledge-sharing networks (e.g. Nordisk Vejforum, and NJS – Forum for Nordisk Jernbanesamarbeid), since the dissolution of the Council of Ministers for Transport in 2005, there has been a lack of a Nordic political platform to discuss cross-border transport infrastructure.Previous research and literature show that cross-border transport infrastructure faces challenges in many different fields. Challenges relating to governance involve, for example, many stakeholders at different levels of government. Economic challenges may relate to, for example, only calculating benefits on one side of a national border or increased costs due to higher insecurity. Among the legal and administrative challenges, we find conflicting laws and regulations; and among the political challenges, a lack of political interest or the risk of altering the balance of power between countries or within a country. Other challenges may relate to differences in technology, calculation models or language.However, research literature and previous findings also highlight opportunities to overcome those challenges. These include establishing clear common goals, promoting transparency, working with relevant stakeholders and ensuring their commitment, allocating benefits and risks, and promoting effective governance. 
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9.
  • Lundgren, Anna, et al. (author)
  • Facilitating cross-border transport infrastructure planning in the Nordic Region
  • 2023
  • Reports (other academic/artistic)abstract
    • Denna rapport är den andra rapporten i forskningsprojektet. Institutionella hinder och möjligheter tillsamordning (Nordic Transport infrastructure planning. Institutional barriers andopportunities for coordination) (2021–2023). Syftet med NORDINFRA är att öka kunskapen om gränsöverskridande transportinfrastruktur i Norden genom att identifiera hinder för gränsöverskridande transportinfrastruktur, peka påmöjligheter och föreslå åtgärder för att underlätta planering av gränsöverskridande transportinfrastruktur. Projektet, som har finansierats av Trafikverket, har letts av Nordregio, och genomförts av forskare från Nordregio och Umeå universitet.I den första rapporten, "Cross-border transport infrastructure planning in the Nordic Region - An introduction" (2023) gavs en bakgrund och fördjupning av hur gränsöverskridande transportinfrastrukturplanering bedrivs inom ramen för de olika planeringssystemen i Danmark, Finland, Norge och Sverige, samt vilken roll den nordiska och EU-kontexten spelar. Den här andra och sista rapporten i projektet bygger på empiri från intervjuer i tre fallstudier av infrastrukturprojekt i tidiga skeden; den fasta HH-förbindelsen mellan Helsingborg och Helsingör, järnvägsförbindelsen Stockholm–Oslo, och länken från Mo i Rana, via Hemavan och Umeå, över Kvarken till Vasa. I intervjuerna med intressenter från fallstudieprojekten har vi ställt frågor om hur de ser på formella och informellahinder för gränsöverskridande transportinfrastrukturplanering, och hur dessa hinder skulle kunna överbryggas. De båda rapporterna är komplementära. Precis som skrivbordsstudierna i den första rapporten visade, bekräftar intervjuerna att gränsöverskridande transportinfrastrukturplanering involverar många aktörer på olika administrativa nivåer, från ministerier och transportmyndigheter på den nationella nivån, till regioner, kommuner, gränsöverskridande organisationer, privata företag och lobbygrupper. Intervjuerna visar också att den nationella nivån och regeringarna har en särskilt central roll då dessa i stor utsträckning sätter ramarna och på så sätt påverkarde övriga aktörernas agerande. Även om våra resultat visar stora utmaningar för gränsöverskridande transportinfrastrukturplanering, har vi även fått exempel på framgångsrika planeringsinsatser och förslag på åtgärder för att ytterligare utveckla transportplaneringen över nationsgränserna. Utmaningarna har sammanfattats i sju nyckelområden:Att acceptera att gränsöverskridande transportinfrastrukturplanering är komplextAtt ha förståelse för att den nationella planeringen förtransportinfrastruktur har en nyckelrollAtt hantera bristen på tydliga uppdrag och mandat för gränsöverskridande transportinfrastrukturplaneringAtt systematiskt dela information och kunskap omtransportinfrastrukturplaneringAtt beakta att gränsöverskridande transportinfrastruktur när allt kommer omkring är en fråga om prioritieringarAtt involvera regionala och andra intressenter i den gränsöverskridande transportinfrastrukturplaneringenAtt lära hantverket om hur man samarbetar kring gränsöverskridande transportinfrastrukturplaneringDen främsta potentialen för att förbättra gränsöverskridande transportinfrastrukturplanering i Norden är beroende av att de nationella regeringarna i högre grad prioriterar det nordiska politiska samarbetet inom transportinfrastruktur. För att utveckla det nordiska samarbetet kring transportinfrastruktur, ska vikten av tydliga mandat och uppdrag inte underskattas. Även om regioner, kommuner, gränsöverskridande organisationer och andra aktörer är viktiga kan de inte ersätta de nationella myndigheternas centrala roll.Genom att skapa en gemensam nordisk kunskapsbas om transportflödena i det nordiska transportsystemet, transportsystemets funktionssätt och om hur investeringar i transportinfrastruktur i ett land påverkar flödena i de andra nordiska länderna, skulle den samlade kunskapsnivån kunna höjas. Denna skulle också kunna fungera som en gemensam nordisk plattform för kunskaps- och erfarenhetsutbyte som bas och för att utveckla strukturer för fördjupat samarbete kring bl.a. gemensamma analysverktyg. Sammantaget bedöms dessainsatser kunna bidra till att underlätta den nordiska gränsöverskridande transportinfrastrukturplaneringen och till att utveckla ett transportsystem som gynnar de nordiska länderna och Norden som helhet.
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