1. |
- Andersson, Charlotta S., et al.
(author)
-
The Mycobacterium tuberculosis Very-Long-Chain Fatty Acyl-CoA Synthetase : Structural Basis for Housing Lipid Substrates Longer than the Enzyme
- 2012
-
In: Structure. - : Elsevier BV. - 0969-2126 .- 1878-4186. ; 20:6, s. 1062-1070
-
Journal article (peer-reviewed)abstract
- The Mycobacterium tuberculosis acid-induced operon MymA encodes the fatty acyl-CoA synthetase FadD13 and is essential for virulence and intracellular growth of the pathogen. Fatty acyl-CoA synthetases activate lipids before entering into the metabolic pathways and are also involved in transmembrane lipid transport. Unlike soluble fatty acyl-CoA synthetases, but like the mammalian integral-membrane very-long-chain acyl-CoA synthetases, FadD13 accepts lipid substrates up to the maximum length tested (C-26). Here, we show that FadD13 is a peripheral membrane protein. The structure and mutational studies reveal an arginine- and aromatic-rich surface patch as the site for membrane interaction. The protein accommodates a hydrophobic tunnel that extends from the active site toward the positive patch and is sealed by an arginine-rich lid-loop at the protein surface. Based on this and previous data, we propose a structural basis for accommodation of lipid substrates longer than the enzyme and transmembrane lipid transport by vectorial CoA-esterification.
|
|
2. |
- Bagerius, Henric, 1974-
(author)
-
Mandom och mödom : Sexualitet, homosocialitet och aristokratisk identitet på det senmedeltida Island
- 2009
-
Doctoral thesis (other academic/artistic)abstract
- The purpose of this study is to show how political and sexual strategies interacted when the Icelandic elite was reorganized in the late Middle Ages. During the years 1262 through 1264, the Icelanders agreed to pay tax to the Norwegian king and thus Iceland evolved into a more organized and hierarchical society. Representing the Norwegian crown, the Icelandic chieftains developed a stronger aristocratic identity. Their mutual understanding grew and so did their sense of being members of a chivalry.Emphasizing certain sexual norms was a way for the elite to define its own group and sexuality functioned as an important component when forming an aristocratic self-image. Through analyses of Icelandic romances and other sources, this dissertation shows that sexuality was frequently used to make distinctions of various kinds. Sexuality served as a marker to distinguish the chivalrous from the common, the human from the monstrous and the masculine from the feminine.In the romances, a homosocial pattern emerges, reflecting changing conceptions of male friendship in the aristocracy. In these narratives, it is the friendship between equal knights that matters. Chivalrous men seek each other's company and the strong bond between them often affect the way they act sexually. A chivalrous knight is able to control his sexual desires and he also considers the consequences of his actions. These characteristics distinguish him from other men in the romances. The heathen, for example, acts without respecting the rules of chivalry. He lacks the ability to reason and his urges cannot be subdued. These traits apply to the berserk as well.Sexuality was also important in distinguishing aristocratic women from other women. In the late Middle Ages, Icelandic aristocrats' interest in virginity increased - partially as a result of a stronger patrilineal way of thinking. However, the aristocratic approach to virginity was tinged with ambivalence. In the romances, there is something both enticing and frightening about the sexuality of young women. The maiden is adored because of her chastity and pure thoughts. On the other hand, her lack of sexual experience makes it difficult for her to control her sexual desires and to resist men. In this regard, the maiden is a source of deep worry.
|
|
3. |
|
|
4. |
- Hermanson, Lars, 1967, et al.
(author)
-
Från höst till vår: Förord
- 2014
-
In: Det våras för medeltiden: Vänbok till Thomas Lindkvist. Red. Audur Magnúsdóttir, Henric Bagerius och Lars Hermanson. - Göteborg : University of Gothenburg. - 9789188614766 ; , s. 13-15
-
Book chapter (other academic/artistic)
|
|
5. |
- Hermanson, Lars, 1967, et al.
(author)
-
Inledning: Medeltidens genus
- 2016
-
In: Medeltidens genus, Red: Lars Hermanson & Auður Magnúsdóttir. - Göteborg : Kriterium / Acta Universitatis Gothoburgensis. - 2002-2131. ; , s. 11-28
-
Book chapter (peer-reviewed)
|
|
6. |
- Holdgaard, Marianne, et al.
(author)
-
Introduction
- 2020
-
In: Nordic Inheritance Law through the Ages: Spaces of Action and Legal Strategies. - Leiden/Boston : Brill. - 9789004427358 ; , s. 1-20
-
Book chapter (peer-reviewed)
|
|
7. |
|
|
8. |
- Lindkvist, Thomas, 1949, et al.
(author)
-
Enhet och mångfald
- 2014
-
In: Maria Sjöberg (red) En samtidig världshistoria. - Lund : Studentlitteratur. - 9789144074375 ; , s. 392-409
-
Book chapter (peer-reviewed)
|
|
9. |
- Lindkvist, Thomas, 1949, et al.
(author)
-
Enhet och mångfald
- 2017
-
In: Maria Sjöberg (red.) En samtidig världshistoria, andra upplagan. - Lund : Studentlitteratur. - 9789144110240 ; , s. 415-432
-
Book chapter (other academic/artistic)
|
|
10. |
- Magnusdottir, Audur, 1959
(author)
-
Becoming visible. Viewing women in Íslendinga saga
- 2017
-
In: Sturla Þórðarson. Skald, Chieftain and Lawman / edited by Jón Viðar Sigurðsson, Sverrir Jakobsson. - Leiden : Brill. - 9789004342354 ; , s. 180-191
-
Book chapter (peer-reviewed)
|
|