| 1. |
- Roslin, Tomas, et al.
(author)
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A molecular-based identification resource for the arthropods of Finland
- 2022
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In: Molecular Ecology Resources. - : Wiley. - 1755-098X .- 1755-0998. ; 22:2, s. 803-822
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Journal article (peer-reviewed)abstract
- To associate specimens identified by molecular characters to other biological knowledge, we need reference sequences annotated by Linnaean taxonomy. In this study, we (1) report the creation of a comprehensive reference library of DNA barcodes for the arthropods of an entire country (Finland), (2) publish this library, and (3) deliver a new identification tool for insects and spiders, as based on this resource. The reference library contains mtDNA COI barcodes for 11,275 (43%) of 26,437 arthropod species known from Finland, including 10,811 (45%) of 23,956 insect species. To quantify the improvement in identification accuracy enabled by the current reference library, we ran 1000 Finnish insect and spider species through the Barcode of Life Data system (BOLD) identification engine. Of these, 91% were correctly assigned to a unique species when compared to the new reference library alone, 85% were correctly identified when compared to BOLD with the new material included, and 75% with the new material excluded. To capitalize on this resource, we used the new reference material to train a probabilistic taxonomic assignment tool, FinPROTAX, scoring high success. For the full-length barcode region, the accuracy of taxonomic assignments at the level of classes, orders, families, subfamilies, tribes, genera, and species reached 99.9%, 99.9%, 99.8%, 99.7%, 99.4%, 96.8%, and 88.5%, respectively. The FinBOL arthropod reference library and FinPROTAX are available through the Finnish Biodiversity Information Facility (www.laji.fi) at https://laji.fi/en/theme/protax. Overall, the FinBOL investment represents a massive capacity-transfer from the taxonomic community of Finland to all sectors of society.
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| 2. |
- Arjonen, Antti, et al.
(author)
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Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis
- 2014
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In: Journal of Clinical Investigation. - : American Society for Clinical Investigation. - 0021-9738 .- 1558-8238. ; 124:3, s. 1069-1082
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Journal article (peer-reviewed)abstract
- Mutations of the tumor suppressor TP53 are present in many forms of human cancer and are associated with increased tumor cell invasion and metastasis. Several mechanisms have been identified for promoting dissemination of cancer cells with TP53 mutations, including increased targeting of integrins to the plasma membrane. Here, we demonstrate a role for the filopodia-inducing motor protein Myosin-X (Myo10) in mutant p53-driven cancer invasion. Analysis of gene expression profiles from 2 breast cancer data sets revealed that MYO10 was highly expressed in aggressive cancer subtypes. Myo10 was required for breast cancer cell invasion and dissemination in multiple cancer cell lines and murine models of cancer metastasis. Evaluation of a Myo10 mutant without the integrin-binding domain revealed that the ability of Myo10 to transport 131 integrins to the filopodia tip is required for invasion. Introduction of mutant p53 promoted Myo10 expression in cancer cells and pancreatic ductal adenocarcinoma in mice, whereas suppression of endogenous mutant p53 attenuated Myo10 levels and cell invasion. In clinical breast carcinomas, Myo10 was predominantly expressed at the invasive edges and correlated with the presence of TP53 mutations and poor prognosis. These data indicate that Myo10 upregulation in mutant p53-driven cancers is necessary for invasion and that plasma-membrane protrusions, such as filopodia, may serve as specialized metastatic engines.
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| 3. |
- Haapakangas, Juho, et al.
(author)
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Coke Reactivity in Simulated Blast Furnace Shaft Conditions
- 2016
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In: Metallurgical and materials transactions. B, process metallurgy and materials processing science. - : Springer Science and Business Media LLC. - 1073-5615 .- 1543-1916. ; 47:4, s. 2357-2370
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Journal article (peer-reviewed)abstract
- Despite the fact that H2 and H2O are always present in the gas atmosphere of a blast furnace shaft, their role in the solution-loss reactions of coke has not been thoroughly examined. This study focuses on how H2 and H2O affect the reaction behavior and whether a strong correlation can be found between reactivity in the conditions of the CRI test (Coke Reactivity Index) and various simulated blast furnace shaft gas atmospheres. Partial replacement of CO/CO2 with H2/H2O was found to significantly increase the reactivity of all seven coke grades at 1373 K (1100 °C). H2 and H2O, however, did not have a significant effect on the threshold temperature of gasification. The reactivity increasing effect was found to be temperature dependent and clearly at its highest at 1373 K (1100 °C). Mathematical models were used to calculate activation energies for the gasification, which were notably lower for H2O gasification compared to CO2 indicating the higher reactivity of H2O. The reactivity results in gas atmospheres with CO2 as the sole gasifying component did not directly correlate with reactivity results in gases also including H2O, which suggests that the widely used CRI test is not entirely accurate for estimating coke reactivity in the blast furnace.
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| 4. |
- Hietanen, Joel, et al.
(author)
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'Managerial Storytelling’ : How we produce managerial and academic stories in qualitative B2B case study research
- 2014
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In: Journal of Global Scholars of Marketing Science. - : Taylor & Francis Group. - 2163-9159 .- 2163-9167. ; 24:3, s. 295-310
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Journal article (peer-reviewed)abstract
- With a focus on case study research methods, this study continues the epistemological debate about qualitative research approaches in the IMP literature by reconsidering the reliance on managerial interviews as a primary empirical source in the production of knowledge claims. In this empirical approach, researchers seem to often treat the interview process and the analysis and reporting of research findings in a manner that generally gives situational credence to the veracity and factuality of the interview data. In line with several epistemological approaches that have already surfaced in IMP literature, this study further emphasizes the context-dependent, ephemeral and ultimately unstable nature of managerial “truths” imparted in the interviews. We argue that the data should be empathically and reflexively understood as the production of stories and their reporting as a form of academic storytelling of pragmatic academic and managerial value.
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| 5. |
- Hietanen, Joel, et al.
(author)
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Paradox and market renewal Knockoffs and counterfeits as doppelganger brand images of luxury
- 2018
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In: Marketing Intelligence & Planning. - England : Emerald Group Publishing Limited. - 0263-4503 .- 1758-8049. ; 36:7, s. 750-763
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Journal article (peer-reviewed)abstract
- Purpose - The purpose of this paper is to continue the emerging stream of literature that has found knockoffs and counterfeits to be unobtrusive or even beneficial to luxury companies by analyzing how they produce paradoxes of meaning and contribute to the renewal of luxury markets. This is done by exploring them as doppelganger brand images that reappropriate brand imagery for their own purposes. Design/methodology/approach - This is a conceptual paper that focuses on the role of knockoffs and counterfeits in the renewal of luxury markets. Findings - The findings highlight how knockoffs and counterfeits can contribute to the emergence and cyclical diffusion of luxury. As luxury offerings are introduced to the market, knockoffs and counterfeits accelerate the snob effect, aid in anchoring trends and contribute to induced obsolescence. During diffusion, knockoffs and counterfeits can strengthen aspiration, bandwagon and herding effects. In doing so, knockoffs and counterfeits create a paradox as they simultaneously legitimize the idea of the authenticity of genuine offerings through their presence in the market and create cyclical demand for novel offerings by undermining the authenticity claims of existing luxury offerings. Thus, knockoffs and counterfeits can be understood as a paradox of luxury markets that contributes to the market cyclicality not despite but because of this paradoxical interplay. Originality/value - While research on knockoffs and counterfeiting is plentiful in the field of marketing, this is among the few studies that analyze how these offerings contribute to luxury markets and their renewal.
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| 6. |
- Hietanen, Joel, et al.
(author)
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Reimagining society through retail practice
- 2016
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In: Journal of Retailing. - : Elsevier BV. - 0022-4359 .- 1873-3271. ; 92:4, s. 411-425
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Journal article (peer-reviewed)abstract
- Marketing scholars with sociological and anthropological leanings have made great strides in uncovering strategic and theoretical implicationsof consumer collectives and consumption-driven market phenomena. It has not been very common that their perspectives have been brought to bearon retailing practice or theory. This ethnographic study examines a highly successful, globalizing, consumer-driven pop-up retail festival for itspotential lessons about social movements. It reveals new insights into logics and potentialities for retailing as a field of affordances for reimaginingsociety and social practices. It points especially to how eruptions of ‘carnivalesque mood’ unite everyday citizens to imagine change in a highlyregulated social context and how they utilize the practice of retailing collectively to actualize societal change.
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| 7. |
- Huhtala, Juho-Petteri, et al.
(author)
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BARRIERS TO INNOVATION DIFFUSION IN INDUSTRIAL NETWORKS : A SYSTEMATIC COMBINING APPROACH
- 2014
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In: Field Guide to Case Study Research in Business-to-Business Marketing and Purchasing. - BINGLEY : EMERALD GROUP PUBLISHING LTD. - 9781784410803 ; , s. 61-76
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Book chapter (peer-reviewed)abstract
- Over the past 50 years, a substantial interest has been put to research on how innovation spreads within social networks over time (see Rogers, 1962, 2010). Our initial aim was to examine innovation diffusion in industrial networks. We operationalized the research through a case study of an advertising network by using systematic combining as the approach (Dubois & Gadde, 2002, 2014). From the initial focus of innovation diffusion, the rematching of data and theory led us to focus on the barriers of innovation diffusion. By doing so, we found out that multilevel strategizing appears to be an important phenomenon in understanding dynamics of innovation diffusion within industrial networks. Specifically, strategizing occurs in two levels: (1) the groups within the network compete for position, and (2) actors within a group compete for position by trying to differentiate themselves from other group actors. A strategic mismatch between the two levels leads the network to become decelerated or even static in diffusing new innovations (Abrahamsen, Henneberg, & Naude, 2012). Uncovering these findings would not have been possible without the use of systematic combining and the constant matching between theoretical and empirical domains.
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| 8. |
- Lahtinen, Hannu, et al.
(author)
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Do Surveys Overestimate or Underestimate Socioeconomic Differences in Voter Turnout? Evidence from Administrative Registers
- 2019
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In: Public Opinion Quarterly. - : Oxford University Press (OUP). - 0033-362X .- 1537-5331. ; 83:2, s. 363-385
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Journal article (peer-reviewed)abstract
- Surveys generally overestimate the overall level of voter turnout in elections due to both the misreporting of voting and nonresponse. It is sometimes argued that socioeconomic differences in turnout are exaggerated in surveys because social desirability has a more pronounced effect on eligible voters in more advantaged socioeconomic positions. However, the contribution of nonresponse bias has not been taken into consideration in these assessments. Using a register-linked survey with information on the education, occupational social class, income, and voting in the 2015 Finnish parliamentary elections of both respondents and nonrespondents, this study shows that nonresponse bias leads to not only a larger overestimation of the overall level of turnout than social desirability, but also an underestimation of educational, social class, and income-related differences in the propensity to vote. Socioeconomic differences in the probability of voting in register-based data were at least two-thirds larger than differences obtained when using standard survey techniques. This finding implies that socioeconomic inequality in electoral participation is a more pressing social problem than previous evidence might indicate.
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| 9. |
- Lahtinen, Hannu, et al.
(author)
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Explaining Social Class Inequality in Voter Turnout : The Contribution of Income and Health
- 2017
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In: Scandinavian Political Studies. - : Wiley. - 0080-6757 .- 1467-9477. ; 40:4, s. 388-410
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Journal article (peer-reviewed)abstract
- Occupation-based social class is an important, yet under-explored, factor in electoral participation. In this article, social class differences in voter turnout over time are measured, and how two other resources - namely income and health - mediate or modify this relationship is analysed. The analysis is based on an individual-level register-based 11 percent sample of the entire electorate in the 1999 Finnish parliamentary elections, and secondarily on smaller register-based samples in the 2012 presidential and municipal elections. Results show that income mediates part of the effects of social class on voting, while social class and utilised health indicators exert mainly independent effects on turnout. Social class differences remain largely stable in all income and hospital care groups, except that no differences between classes are observed among those most severely affected by health problems. Results are also mostly similar between those of working age and the older population, and between men and women, and remain stable over time and in different types of elections. The findings imply that social class should be taken account in theoretical and empirical models of turnout.
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| 10. |
- Mack, Leoni, et al.
(author)
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A Synthesis of Marine Monitoring Methods With the Potential to Enhance the Status Assessment of the Baltic Sea
- 2020
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In: Frontiers in Marine Science. - Lausanne : Frontiers Media S.A.. - 2296-7745. ; 7
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Journal article (peer-reviewed)abstract
- A multitude of anthropogenic pressures deteriorate the Baltic Sea, resulting in theneed to protect and restore its marine ecosystem. For an efficient conservation,comprehensive monitoring and assessment of all ecosystem elements is of fundamentalimportance. The Baltic Marine Environment Protection Commission HELCOMcoordinates conservation measures regulated by several European directives. However,this holistic assessment is hindered by gaps within the current monitoring schemes.Here, twenty-two novel methods with the potential to fill some of these gaps andimprove the monitoring of the Baltic marine environment are examined. We asked keystakeholders to point out methods likely to improve current Baltic Sea monitoring. Wethen described these methods in a comparable way and evaluated them based ontheir costs and applicability potential (i.e., possibility to make them operational). Twelvemethods require low to very low costs, while five require moderate and two high costs.Seventeen methods were rated with a high to very high applicability, whereas fourmethods had moderate and one low applicability for Baltic Sea monitoring. Methodswith both low costs and a high applicability include the Manta Trawl, Rocket, SedimentCorer, Argo Float, Artificial Substrates, Citizen Observation, Earth Observation, theHydroFIARpH system, DNA Metabarcoding and Stable Isotope Analysis. © 2020 Mack, Attila, Aylagas, Beermann, Borja, Hering, Kahlert, Leese, Lenz, Lehtiniemi, Liess, Lips, Mattila, Meissner, Pyhälahti, Setälä, Strehse, Uusitalo, Willstrand Wranne and Birk.
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