↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Träfflista för sökning "WFRF:(Mellqvist UH) "

Search: WFRF:(Mellqvist UH)

Result 1-10 of 18

Sort/group result

Sort by: Hits per page:

Enumeration	Reference	Cover	Find
1.	Ali, Mina, et al. (author) The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression 2018 In: Nature communications. - : Springer Science and Business Media LLC. - 2041-1723. ; 9:1, s. 1649- Journal article (peer-reviewed)abstract Recently, we identified ELL2 as a susceptibility gene for multiple myeloma (MM). To understand its mechanism of action, we performed expression quantitative trait locus analysis in CD138+ plasma cells from 1630 MM patients from four populations. We show that the MM risk allele lowers ELL2 expression in these cells (Pcombined = 2.5 × 10−27; βcombined = −0.24 SD), but not in peripheral blood or other tissues. Consistent with this, several variants representing the MM risk allele map to regulatory genomic regions, and three yield reduced transcriptional activity in plasmocytoma cell lines. One of these (rs3777189-C) co-locates with the best-supported lead variants for ELL2 expression and MM risk, and reduces binding of MAFF/G/K family transcription factors. Moreover, further analysis reveals that the MM risk allele associates with upregulation of gene sets related to ribosome biogenesis, and knockout/knockdown and rescue experiments in plasmocytoma cell lines support a cause–effect relationship. Our results provide mechanistic insight into MM predisposition.
2.	Baldursdottir, TR, et al. (author) Autoimmune disease is associated with a lower risk of progression in monoclonal gammopathy of undetermined significance 2021 In: European journal of haematology. - : Wiley. - 1600-0609 .- 0902-4441. ; 106:3, s. 380-388 Journal article (peer-reviewed)
3.	Blimark, C, et al. (author) Multiple Myeloma and Infections: A Population-Based Study Based On 9,610 Multiple Myeloma Patients 2012 In: BLOOD. - 0006-4971. ; 120:21 Conference paper (other academic/artistic)
4.	de Larrea, CF, et al. (author) Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group 2013 In: Leukemia. - : Springer Science and Business Media LLC. - 1476-5551 .- 0887-6924. ; 27:4, s. 780-791 Journal article (peer-reviewed)
5.	Falk, IJ, et al. (author) The impact of ABCB1 single nucleotide polymorphisms on the outcome in lenalidomide treated multiple myeloma patients 2017 In: CANCER RESEARCH. - 0008-5472. ; 77 Conference paper (other academic/artistic)
6.	Heeg, B, et al. (author) Treatment Sequencing Survival Model for Patients with Multiple Myeloma Ineligible for Stem Cell Transplantation (SCT) 2014 In: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. - : Elsevier BV. - 1524-4733. ; 17:7, s. A617-A618 Journal article (peer-reviewed)
7.	Hellstrand, K, et al. (author) Histamine and interleukin-2 in acute myelogenous leukemia 1997 In: Leukemia & lymphoma. - : Informa UK Limited. - 1042-8194 .- 1029-2403. ; 27:5-6, s. 429-438 Journal article (peer-reviewed)
8.	Kristinsson, SY, et al. (author) Monoclonal Gammopathy of Undetermined Significance and Risk of Infections: A Population-Based Study. 2010 In: BLOOD. - 0006-4971. ; 116:21, s. 1652-1652 Conference paper (other academic/artistic)
9.	Kumar, S, et al. (author) Natural History of Relapsed Myeloma, Refractory to Immunomodulatory Drugs and Proteasome Inhibitors: A Multicenter IMWG Study 2016 In: BLOOD. - 0006-4971. ; 128:22 Conference paper (other academic/artistic)
10.	Landgren, O, et al. (author) Increased risk of monoclonal gammopathy of undetermined significance (MGUS) and lymphoproliferative tumors among 14689 first-degree relatives of 4488 MGUS patients in Sweden 2007 In: BLOOD. - 0006-4971. ; 110:11, s. 203A-203A Conference paper (other academic/artistic)

Skapa referenser, mejla, bekava och länka

Permalink

Result 1-10 of 18

Refine your search

Type of publication: conference paper (9); journal article (9)

Type of content: other academic/artistic (9); peer-reviewed (9)

Author/Editor: Mellqvist, UH (18); Nahi, H (8); Turesson, I (7); Waage, A (7); Hansson, M (5); Landgren, O (5); show more...; Goldschmidt, H (5); Ludwig, H (4); Moreau, P (4); Bjorkholm, M (4); GRUBER, A (4); Plesner, T (3); Chng, WJ (3); Stephens, OW (3); Weinhold, N (3); Kumar, S (2); EASTON, D (2); Brune, M (2); Hari, P (2); Hansson, Markus (2); Turesson, Ingemar (2); Alici, E (2); Hoffmann, P (2); Sud, A (2); Nothen, MM (2); Nilsson, Björn (2); Lund, J. (2); Swerdlow, A (2); Muir, K (2); Peto, J (2); Gullberg, Urban (2); Hemminki, K (2); Hou, J (2); Nilsson, B (2); Pharoah, P (2); Wahlin, A (2); Hemminki, Kari (2); Langer, C. (2); Kuiper, R (2); Kote-Jarai, Z (2); Canzian, F (2); Pashayan, N (2); Eeles, RA (2); Li, N (2); Thomsen, H (2); Ali, Mina (2); Wihlborg, Anna-Karin (2); Johnsson, Ellinor (2); Thorleifsson, G (2); Thorsteinsdottir, U (2); show less...

University: Karolinska Institutet (18); Lund University (3); Uppsala University (1)

Language: English (18)

Research subject (UKÄ/SCB): Medical and Health Sciences (3)

Year

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

Copyright © LIBRIS - National Library Systems
LIBRIS.kb.se

pil uppåt

Close

Copy and save the link in order to return to this view