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- Guido, Davide, et al.
(author)
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Pain rates in general population for the period 1991-2015 and 10-years prediction : results from a multi-continent age-period-cohort analysis
- 2020
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In: Journal of Headache and Pain. - : Springer Science and Business Media LLC. - 1129-2369 .- 1129-2377. ; 21:1
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Journal article (peer-reviewed)abstract
- Background Pain is a common symptom, often associated with neurological and musculoskeletal conditions, and experienced especially by females and by older people. The aims of this study are to evaluate the temporal variations of pain rates among general populations for the period 1991-2015 and to project 10-year pain rates. Methods We used the harmonized dataset of ATHLOS project, which included 660,028 valid observations in the period 1990-2015 and we applied Bayesian age-period-cohort modeling to perform projections up to 2025. The harmonized Pain variable covers the content self-reported pain experienced at the time of the interview, with a dichotomous (yes or no) modality. Results Pain rates were higher among females, older subjects, in recent periods, and among observations referred to cohorts of subjects born between the 20s and the 60s. The 10-year projections indicate a noteworthy increase in pain rates in both genders and particularly among subjects aged 66 or over, for whom a 10-20% increase in pain rate is foreseen; among females only, a 10-15% increase in pain rates is foreseen for those aged 36-50. Conclusions Projected increase in pain rates will require specific interventions by health and welfare systems, as pain is responsible for limited quality of subjective well-being, reduced employment rates and hampered work performance. Worksite and lifestyle interventions will therefore be needed to limit the impact of projected higher pain rates.
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| 2. |
- Guido, Maria Angela, et al.
(author)
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Climate and vegetation dynamics of the Northern Apennines (Italy) during the Late Pleistocene and Holocene
- 2020
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In: Quaternary Science Reviews. - : Elsevier BV. - 0277-3791. ; 231, s. 1-17
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Journal article (peer-reviewed)abstract
- This study reconstructs the regional vegetation and climate dynamics between the upper Late Pleistoceneand Holocene around Pian del Lago, a coastal mountain marshland located at 831 m asl in westernLiguria (NW-Italy), based on the pollen analysis of a 13 m-long sediment core. The record provided aunique opportunity to study a poorly documented period in northern Italy and across many parts ofsouthwestern Europe. We propose an event stratigraphy based upon the identification of seven interstadials(NAI-7 to NAI-1) spanning the upper Late Pleistocene. The correlation with other terrestrialrecords in Italy, and with Mediterranean marine sequences and the Greenland ice cores, permitted acoherent reconstruction of main environmental changes from >~43,000 cal. BP. Significantly, the pollenrecord indicates the persistence of a mesophilous mountain vegetation cover, mainly composed ofQuercus (deciduous and evergreen), Abies, Fagus and Alnus over the whole time period recorded. At theLast Glacial Maximum (LGM) and during the Late Würm Lateglacial, despite the presence of steppicvegetation composed of Artemisia, woodlands dominated by Pinus, with Abies, Picea, Fagus, Alnus andBetula are present. This forest composition provides an important insight into the history of Picea insouthern Europe and Late Pleistocene refugia for mesophilous species. During the Early Holocene, Pinusis first replaced by Abies and then by deciduous Quercus and mixed temperate species as the dominantforest component. Both arboreal and herbaceous anthropogenic pollen indicators only make theirappearance during the Late Holocene, attesting to the increasing importance of human activities.
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