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1.
  • Björklund, Svante, 1968- (author)
  • Signal Processing for Radar with Array Antennas and for Radar with Micro-Doppler Measurements
  • 2017
  • Doctoral thesis (other academic/artistic)abstract
    • Radar (RAdio Detection And Ranging) uses radio waves to detect the presence of a target and measure its position and other properties. This sensor has found many civilian and military applications due to advantages such as possible large surveillance areas and operation day and night and in all weather. The contributions of this thesis are within applied signal processing for radar in two somewhat separate research areas: 1) radar with array antennas and 2) radar with micro-Doppler measurements.Radar with array antennas: An array antenna consists of several small antennas in the same space as a single large antenna. Compared to a traditional single-antenna radar, an array antenna radar gives higher flexibility, higher capacity, several radar functions simultaneously and increased reliability, and makes new types of signal processing possible which give new functions and higher performance.The contributions on array antenna radar in this thesis are in three different problem areas. The first is High Resolution DOA (Direction Of Arrival) Estimation (HRDE) as applied to radar and using real measurement data. HRDE is useful in several applications, including radar applications, to give new functions and improve the performance. The second problem area is suppression of interference (clutter, direct path jamming and scattered jamming) which often is necessary in order to detect and localize the target. The thesis presents various results on interference signal properties, antenna geometry and subarray design, and on interference suppression methods. The third problem area is measurement techniques for which the thesis suggests two measurement designs, one for radar-like measurements and one for scattered signal measurements.Radar with micro-Doppler measurements: There is an increasing interest and need for safety, security and military surveillance at short distances. Tasks include detecting targets, such as humans, animals, cars, boats, small aircraft and consumer drones; classifying the target type and target activity; distinguishing between target individuals; and also predicting target intention. An approach is to employ micro-Doppler radar to perform these tasks. Micro-Doppler is created by the movement of internal parts of the target, like arms and legs of humans and animals, wheels of cars and rotors of drones.Using micro-Doppler, this thesis presents results on feature extraction for classification; on classification of targets types (humans, animals and man-made objects) and human gaits; and on information in micro-Doppler signatures for re-identification of the same human individual. It also demonstrates the ability to use different kinds of radars for micro-Doppler measurements. The main conclusion about micro-Doppler radar is that it should be possible to use for safety, security and military surveillance applications.
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2.
  • Endres, Dominique, et al. (author)
  • Immunological causes of obsessive-compulsive disorder : is it time for the concept of an "autoimmune OCD" subtype?
  • 2022
  • In: Translational Psychiatry. - : Springer Nature. - 2158-3188. ; 12:1
  • Research review (peer-reviewed)abstract
    • Obsessive-compulsive disorder (OCD) is a highly disabling mental illness that can be divided into frequent primary and rarer organic secondary forms. Its association with secondary autoimmune triggers was introduced through the discovery of Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection (PANDAS) and Pediatric Acute onset Neuropsychiatric Syndrome (PANS). Autoimmune encephalitis and systemic autoimmune diseases or other autoimmune brain diseases, such as multiple sclerosis, have also been reported to sometimes present with obsessive-compulsive symptoms (OCS). Subgroups of patients with OCD show elevated proinflammatory cytokines and autoantibodies against targets that include the basal ganglia. In this conceptual review paper, the clinical manifestations, pathophysiological considerations, diagnostic investigations, and treatment approaches of immune-related secondary OCD are summarized. The novel concept of "autoimmune OCD" is proposed for a small subgroup of OCD patients, and clinical signs based on the PANDAS/PANS criteria and from recent experience with autoimmune encephalitis and autoimmune psychosis are suggested. Red flag signs for "autoimmune OCD" could include (sub)acute onset, unusual age of onset, atypical presentation of OCS with neuropsychiatric features (e.g., disproportionate cognitive deficits) or accompanying neurological symptoms (e.g., movement disorders), autonomic dysfunction, treatment resistance, associations of symptom onset with infections such as group A streptococcus, comorbid autoimmune diseases or malignancies. Clinical investigations may also reveal alterations such as increased levels of anti-basal ganglia or dopamine receptor antibodies or inflammatory changes in the basal ganglia in neuroimaging. Based on these red flag signs, the criteria for a possible, probable, and definite autoimmune OCD subtype are proposed.
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