| 1. |
- Frostfeldt, Gunnar, et al.
(author)
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Low molecular weight heparin (Dalteparin) as adjuvant treatment to thrombolysis in acute myocardial infarction-a pilot study : BIOchemical markers in acute coronary syndromes (BIOMACS II)
- 1999
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In: Journal of the American College of Cardiology. - 0735-1097 .- 1558-3597. ; 33:3, s. 627-633
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Journal article (peer-reviewed)abstract
- OBJECTIVES: This randomized, double blind, placebo-controlled pilot trial evaluated the effect of dalteparin as an adjuvant to thrombolysis in patients with acute myocardial infarction regarding early reperfusion, recurrent ischemia and patency at 24 h. BACKGROUND: Low-molecular-weight heparin, given subcutaneously twice daily without monitoring, might be an attractive alternative to conventional intravenous heparin in the treatment of acute myocardial infarction. METHODS: In 101 patients dalteparin/placebo 100 IU/kg was given just before streptokinase and a second injection 120 IU/kg after 12 h. Monitoring with continuous vector-ECG was done to obtain signs of early reperfusion and later ischemic episodes. Blood samples for myoglobin were obtained at start and after 90 min to evaluate signs of reperfusion. Coronary angiography was performed after 20-28 h to evaluate TIMI-flow in the infarct-related artery. RESULTS: Dalteparin added to streptokinase tended to provide a higher rate of TIMI grade 3 flow in infarct-related artery compared to placebo, 68% versus 51% (p = 0.10). Dalteparin had no effects on noninvasive signs of early reperfusion. In patients with signs of early reperfusion, there seemed to be a higher rate of TIMI grade 3 flow, 74% versus 46% (myoglobin) (p = 0.04) and 73% versus 52% (vector-ECG) (p = 0.11). Ischemic episodes 6-24 h. after start of treatment were fewer in the dalteparin group, 16% versus 38% (p = 0.04). CONCLUSIONS: When dalteparin was added as an adjuvant to streptokinase and aspirin, there were tendencies for less ECG monitoring evidence of recurrent ischemia and better patency at 24 h, warranting further study.
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| 2. |
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| 3. |
- Frostfeldt, Gunnar, et al.
(author)
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Possible reasons for the prognostic value of troponin-T on admission in patients with ST-elevation myocardial infarction
- 2001
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In: Coronary Artery Disease. - 0954-6928 .- 1473-5830. ; 12:3, s. 227-237
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Journal article (peer-reviewed)abstract
- BACKGROUND: In patients with acute myocardial infarction and ST-segment elevation, increased troponin-T (TnT) on admission implies an increased mortality. OBJECTIVE: To elucidate the underlying mechanisms of the prognostic value of TnT. METHODS AND RESULTS: One hundred and one patients were included and all received thrombolytic treatment. The patients were compared according to TnT level on admission (cut-off 0.1 microg/l). Elevation of TnT was associated with long-term mortality and also with longer delay, more episodes of chest pain during the last 24 h and fewer noninvasive signs of reperfusion at 90 min. In the group with elevated TnT, the coronary angiography at 24 h showed a strong trend towards lower patency in the infarct-related artery. TnT was also associated with increased infarct size if a higher cut-off level (0.43 microg/l) was used. In univariate analysis, elevated TnT, longer delay, repeated chest pain, Q-waves on admission and reduced left ventricular (LV) function were significantly associated with long-term mortality. In multivariate models, only reduced LV function and less than TIMI (thrombolysis in myocardial infarction) grade 3 flow turned out to be significant independent risk factors. CONCLUSIONS: The prognostic value of TnT level on admission regarding long-term mortality was confirmed and seems mainly to be explained by its association with longer delay and recent myocardial damage, but its association with reduced effect of thrombolytic treatment, larger infarct size and impaired LV function might also be of importance.
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| 4. |
- Andersson, Ewa, 1980-
(author)
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Oberoendets praktik
- 2013
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Doctoral thesis (other academic/artistic)abstract
- The Independent PracticeDuring the last hundred years, the music industry has evolved with the record labels playing a central role. However, many argue that this situation is about to change as record sales have decreased during the last ten years. This imminent change in the music industry will not only affect the multinational record labels, but also the independent record labels. As record sales have decreased during the last ten years, the number of members in the Swedish Independent Music Producers Association (SOM) has increased and the association now includes 300 independent record labels which are responsible for around 30 percent of the music being produced in Sweden. However, they can be considered a dominated group within the music industry, since they only have around 10 percent of the total market shares when it comes to selling figures. Considering the changes in record sales, the domination of the major record labels and the somewhat fascinating growth of independent actors during turbulent times, this thesis will study how the Swedish independent actors relate to the practices and ideals relevant in the daily work of running an independent record label. The practices studied in this thesis are the practice of work, the practice of recognition and the practice of content production.The purpose of this thesis is to analyse how independence is constructed among the members of SOM. The thesis is based on material collected in a web survey as well as seven interviews with representatives of indie labels. The web survey was distributed to all members of SOM, and the interviewed informants were selected by snowball sampling, using a locator to find informants. The survey material was analysed with cluster and variance analysis, while the interview material was analysed using content analysis – searching for themes connected to the practices. All material is understood through the theoretical frame of the field theory.The main results of the study are that there are different ways of relating to practices among the Swedish independent actors, and that these ways of relating are closely connected to their position within the field. There are common ways of relating to practices such as always promoting DIY, the importance of music and the need to resist the dominance of the major labels. However, the independent actors are not consistent in how these commonalities work in practice. For example, DIY is not applied if it is not economically necessary, and the need to resist the major labels is only apparent when the independent actor has a weaker position within the field. The more established an independent actor is within the field, the lesser resistant he is against the dominating structures of the music industry. As a result of a weakening resistance against the major labels, the independent actors turn to struggle each other.
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| 5. |
- Anikina, Maria, et al.
(author)
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A cross-national survey
- 2013
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In: Journalists in three media systems. - Moscow : Journalism Faculty, Lomonosov Moscow State University. ; , s. 30-34
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Book chapter (other academic/artistic)
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| 6. |
- Appelberg, Jonas, 1985-, et al.
(author)
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Social media in the professional work of Polish, Russian and Swedish journalists
- 2014
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In: Journal of Print and Media Technology Research. - Darmstadt : International Association of Research Organizations for the Information, Media and Graphic Arts Industrie (IARIGAI). - 2223-8905 .- 2414-6250. ; 3:2, s. 107-118
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Journal article (peer-reviewed)abstract
- Professional journalistic culture is a complex of journalistic values, practices, norms and media products. On the one hand it tends to unification across the globe, but on the other hand these cultures varies according to cultural diversities. Technological development leads to a media convergence, increasing interactivity and plenty of opportunities for individualization of media content influence audience’s demands and consequently challenge of traditional routine of journalists’ work, affect professional practices and even undermine traditional role of a journalist in society. Social media creates new conditions for both actors: readers/viewers/listeners and for media professionals who use it as a tool for media work. Journalists in the different countries, however, use social media for professional needs not equally. This paper is discussing differences and similarities in the patterns of social media use by Polish, Russian and Swedish journalists. The research is based on a survey of 500 journalists in each country.
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| 7. |
- Appelgren, Ester, 1977-, et al.
(author)
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Data Journalism : Implications and Opportunities
- 2012
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In: Digital Humanities Congress 2012, The University of Sheffield. - Sheffield : HRI Online Publications. ; , s. 60-
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Conference paper (other academic/artistic)abstract
- Data journalism is a form of storytelling where elements of text, interactive graphics and datasets are often combined into one interactive journalistic project or service. In addition, the general public are often encouraged to submit their own data for publication within the service. Data journalism is not a new field, but due to the expensive production process and the advanced skills needed by journalists, it is still relatively uncommon in the Swedish media landscape. This study is based on a joint research project together with SVT Pejl, the data journalism department at the Sveriges television (SVT). The main aim of this paper is to explore this emerging form of interactive journalism based on public sector data, and how the general public engages with it. This paper is based on a four-month case study in 2011 and 2012 of SVT Pejl and “Brottspejl”one of its data journalism services. An action research approach has been used, and the methods were in-depth interviews and a web-based survey.
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| 8. |
- Appelgren, Ester, 1977-, et al.
(author)
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Data Journalism In Sweden : Introducing new methods and genres of journalism into “old” organizations
- 2014
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In: Digital Journalism. - : Routledge. - 2167-0811 .- 2167-082X. ; 2:3, s. 394-405
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Journal article (peer-reviewed)abstract
- Data journalism is an evolving form of investigative journalism. In previous research andhandbooks published on this topic, this form of journalism has been called computer-assistedreporting and data-driven journalism, as well as precision, computational or database journalism.In Sweden, data journalism is still fairly uncommon. The purpose of this paper is to providean overview of the development of data journalism at seven Swedish traditional mediacompanies, using action research methods. The content of this paper is based on an onlinesurvey of journalists and in-depth interviews with editors at these participating companies. Theresults indicate that, based on how this field is currently perceived by journalists in the interviews,there is a common definition of data journalism. Furthermore, the survey shows thatthe attitudes towards data journalism during the process of introducing new methods andgenres of journalism into “old” organizations are correlated with the level of perceived experiencein data journalism working methods. The main challenges facing the working methodsof data journalism today are a shortage of time and the need for training and developingdata journalism skills.
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| 9. |
- Appelgren, Ester, 1977-, et al.
(author)
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HiPPOs (Highest Paid Person’s Opinion) in the Swedish media industry on innovation : A study of news media leaders’ attitudes towards innovation
- 2019
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In: The Journal of Media Innovations. - Oslo : University of Oslo. - 1894-5562. ; 5:1, s. 45-60
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Journal article (peer-reviewed)abstract
- Decades of change in the media landscape and technological innovation have brought several uncertainties to media leadership. In this study, we build on the upper echelons theory to discuss the possible isomorphic behaviour of media leaders. Based on a survey of 372 Swedish media leaders, our results indicate that while innovation is considered to be a strength at media companies, innovation work may still stand in contrast to the institutional perspective. We found that Swedish media leaders perceive innovation as highly important and something they are good at. The perceived ability to work with innovation inside the organizations (rather than introducing knowledge from outside expertise) is undermined by the fact that, during the average work week, the majority of leaders set aside very little time for developing their own competences, individual talks with their employees, and time to reflect on their own work. Thus, in line with upper echelons theory, we find a paradox of trust in in-house innovative strength and, at the same time, media leaders fall back on their own experiences, limiting the inflow of new ideas into their strategic work.
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| 10. |
- Asberg, Marie, et al.
(author)
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Novel biochemical markers of psychosocial stress in women.
- 2009
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In: PloS one. - : Public Library of Science (PLoS). - 1932-6203. ; 4:1
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Journal article (peer-reviewed)abstract
- BACKGROUND: Prolonged psychosocial stress is a condition assessed through self-reports. Here we aimed to identify biochemical markers for screening and early intervention in women. METHODS: Plasma concentrations of interleukin (IL) 1-alpha, IL1-beta, IL-2, IL-4, IL-6, IL-8, IL-10, interferon-gamma (INF-gamma), tumor necrosis factor-alpha (TNF-alpha), monocyte chemotactic protein-1 (MCP-1), epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), thyroid stimulating hormone (TSH), total tri-iodothyronine (TT3), total thyroxine (TT4), prolactin, and testosterone were measured in: 195 women on long-term sick-leave for a stress-related affective disorder, 45 women at risk for professional burnout, and 84 healthy women. RESULTS: We found significantly increased levels of MCP-1, VEGF and EGF in women exposed to prolonged psychosocial stress. Statistical analysis indicates that they independently associate with a significant risk for being classified as ill. CONCLUSIONS: MCP-1, EGF, and VEGF are potential markers for screening and early intervention in women under prolonged psychosocial stress.
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