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Träfflista för sökning "WFRF:(Pedersen Henrik) "

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1.	Allesøe, Rosa Lundbye, et al. (author) Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models 2023 In: Nature Biotechnology. - : Springer Nature. - 1087-0156 .- 1546-1696. ; 41:3, s. 399-408 Journal article (peer-reviewed)abstract The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal data makes integration and inference a non-trivial task. We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate such data and applied it to a cohort of 789 people with newly diagnosed type 2 diabetes with deep multi-omics phenotyping from the DIRECT consortium. Using in silico perturbations, we identified drug–omics associations across the multi-modal datasets for the 20 most prevalent drugs given to people with type 2 diabetes with substantially higher sensitivity than univariate statistical tests. From these, we among others, identified novel associations between metformin and the gut microbiota as well as opposite molecular responses for the two statins, simvastatin and atorvastatin. We used the associations to quantify drug–drug similarities, assess the degree of polypharmacy and conclude that drug effects are distributed across the multi-omics modalities.
2.	Aad, G, et al. (author) ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider. 2015 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:10 Journal article (peer-reviewed)
3.	Aad, G, et al. (author) Constraints on the off-shell Higgs boson signal strength in the high-mass ZZ and WW final states with the ATLAS detector. 2015 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:7 Journal article (peer-reviewed)
4.	Aad, G, et al. (author) Determination of the Ratio of b-Quark Fragmentation Fractions f_{s}/f_{d} in pp Collisions at sqrt[s]=7 TeV with the ATLAS Detector. 2015 In: Physical Review Letters. - : American Physical Society. - 1079-7114 .- 0031-9007. ; 115:26 Journal article (peer-reviewed)
5.	Aad, G, et al. (author) Measurement of Spin Correlation in Top-Antitop Quark Events and Search for Top Squark Pair Production in pp Collisions at sqrt[s]=8 TeV Using the ATLAS Detector. 2015 In: Physical Review Letters. - : Elsevier. - 1079-7114 .- 0031-9007. ; 114:14 Journal article (peer-reviewed)
6.	Aad, G, et al. (author) Performance of the ATLAS muon trigger in pp collisions at [Formula: see text] TeV. 2015 In: The European Physical Journal C. - : Springer Science and Business Media LLC. - 1434-6052. ; 75:3 Journal article (peer-reviewed)
7.	Aad, G, et al. (author) Search for invisible decays of the Higgs boson produced in association with a hadronically decaying vector boson in pp collisions at [Formula: see text] TeV with the ATLAS detector. 2015 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:7 Journal article (peer-reviewed)
8.	Aad, G, et al. (author) Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at [Formula: see text]TeV with the ATLAS detector. 2015 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:7 Journal article (peer-reviewed)
9.	Aad, G, et al. (author) Search for single top-quark production via flavour-changing neutral currents at 8 TeV with the ATLAS detector. 2016 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 76 Journal article (peer-reviewed)
10.	Aad, G, et al. (author) Study of the spin and parity of the Higgs boson in diboson decays with the ATLAS detector. 2015 In: European Physical Journal C. Particles and Fields. - : Springer Science and Business Media LLC. - 1434-6044 .- 1434-6052. ; 75:10 Journal article (peer-reviewed)

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Type of publication: journal article (473); conference paper (28); doctoral thesis (19); reports (8); other publication (8); research review (6); show more...; book chapter (5); book (3); licentiate thesis (3); show less...

Type of content: peer-reviewed (496); other academic/artistic (54); pop. science, debate, etc. (3)

Author/Editor: Chen, L (157); Aad, G (157); Abbott, B. (157); Abdinov, O (157); Zwalinski, L. (157); Gregersen, K. (157); show more...; Poettgen, R. (157); Aben, R. (157); Abreu, H. (157); Adye, T. (157); Ahmadov, F. (157); Aielli, G. (157); Albrand, S. (157); Aleksa, M. (157); Aleksandrov, I. N. (157); Alexander, G. (157); Alexopoulos, T. (157); Alhroob, M. (157); Alimonti, G. (157); Alio, L. (157); Alonso, A. (157); Alonso, F. (157); Alpigiani, C. (157); Altheimer, A. (157); Amako, K. (157); Amelung, C. (157); Amorim, A. (157); Amoroso, S. (157); Amram, N. (157); Amundsen, G. (157); Anastopoulos, C. (157); Ancu, L. S. (157); Andari, N. (157); Andeen, T. (157); Anders, G. (157); Anderson, K. J. (157); Andreazza, A. (157); Angerami, A. (157); Anghinolfi, F. (157); Anjos, N. (157); Annovi, A. (157); Antonelli, M. (157); Antonov, A. (157); Anulli, F. (157); Aoki, M. (157); Arabidze, G. (157); Arai, Y. (157); Argyropoulos, S. (157); Arnaez, O. (157); Arslan, O. (157); show less...

University: Lund University (279); Uppsala University (207); Stockholm University (180); Linköping University (171); Royal Institute of Technology (168); Karolinska Institutet (57); show more...; University of Gothenburg (40); Örebro University (27); Umeå University (19); Chalmers University of Technology (12); Swedish University of Agricultural Sciences (8); Jönköping University (6); Mid Sweden University (5); University of Gävle (3); University of Skövde (3); Mälardalen University (2); Luleå University of Technology (1); Halmstad University (1); Malmö University (1); Stockholm School of Economics (1); The Swedish School of Sport and Health Sciences (1); RISE (1); Högskolan Dalarna (1); Swedish Museum of Natural History (1); Blekinge Institute of Technology (1); Sophiahemmet University College (1); show less...

Language: English (544); Swedish (8); Danish (1)

Research subject (UKÄ/SCB): Natural sciences (325); Medical and Health Sciences (154); Engineering and Technology (21); Social Sciences (8); Agricultural Sciences (7); Humanities (3)

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