| 1. |
- Niemi, MEK, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Athan, E., et al.
(författare)
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Influence of vancomycin minimum inhibitory concentration on the outcome of methicillin-susceptible Staphylococcus aureus left-sided infective endocarditis treated with antistaphylococcal β-lactam antibiotics: a prospective cohort study by the International Collaboration on Endocarditis
- 2017
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Ingår i: Clinical Microbiology and Infection. - : Elsevier BV. - 1198-743X .- 1469-0691. ; 23, s. 544-549
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Tidskriftsartikel (refereegranskat)abstract
- © 2017 European Society of Clinical Microbiology and Infectious Diseases Objectives Left-sided methicillin-susceptible Staphylococcus aureus (MSSA) endocarditis treated with cloxacillin has a poorer prognosis when the vancomycin minimum inhibitory concentration (MIC) is ≥1.5 mg/L. We aimed to validate this using the International Collaboration on Endocarditis cohort and to analyse whether specific genetic characteristics were associated with a high vancomycin MIC (≥1.5 mg/L) phenotype. Methods All patients with left-sided MSSA infective endocarditis treated with antistaphylococcal β-lactam antibiotics between 2000 and 2006 with available isolates were included. Vancomycin MIC was determined by Etest as either high (≥1.5 mg/L) or low (<1.5 mg/L). Isolates underwent spa typing to infer clonal complexes and multiplex PCR for identifying virulence genes. Univariate analysis was performed to evaluate the association between in-hospital and 1-year mortality, and vancomycin MIC phenotype. Results Sixty-two cases met the inclusion criteria. Vancomycin MIC was low in 28 cases (45%) and high in 34 cases (55%). No significant differences in patient demographic data or characteristics of infection were observed between patients with infective endocarditis due to high and low vancomycin MIC isolates. Isolates with high and low vancomycin MIC had similar distributions of virulence genes and clonal lineages. In-hospital and 1-year mortality did not differ significantly between the two groups (32% (9/28) vs. 27% (9/34), p 0.780; and 43% (12/28) vs. 29% (10/34), p 0.298, for low and high vancomycin MIC respectively). Conclusions In this international cohort of patients with left-sided MSSA endocarditis treated with antistaphylococcal β-lactams, vancomycin MIC phenotype was not associated with patient demographics, clinical outcome or virulence gene repertoire.
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| 3. |
- Duffy, J. Emmett, et al.
(författare)
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A Pleistocene legacy structures variation in modern seagrass ecosystems
- 2022
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 119:32
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Tidskriftsartikel (refereegranskat)abstract
- Distribution of Earth's biomes is structured by the match between climate and plant traits, which in turn shape associated communities and ecosystem processes and services. However, that climate-trait match can be disrupted by historical events, with lasting ecosystem impacts. As Earth's environment changes faster than at any time in human history, critical questions are whether and how organismal traits and ecosystems can adjust to altered conditions. We quantified the relative importance of current environmental forcing versus evolutionary history in shaping the growth form (stature and biomass) and associated community of eelgrass (Zostera marina), a widespread foundation plant of marine ecosystems along Northern Hemisphere coastlines, which experienced major shifts in distribution and genetic composition during the Pleistocene. We found that eelgrass stature and biomass retain a legacy of the Pleistocene colonization of the Atlantic from the ancestral Pacific range and of more recent within-basin bottlenecks and genetic differentiation. This evolutionary legacy in turn influences the biomass of associated algae and invertebrates that fuel coastal food webs, with effects comparable to or stronger than effects of current environmental forcing. Such historical lags in phenotypic acclimatization may constrain ecosystem adjustments to rapid anthropogenic climate change, thus altering predictions about the future functioning of ecosystems.
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| 4. |
- Joshi, Bhavin A., et al.
(författare)
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Evidence for Shock-heated Gas in the Taffy Galaxies and Bridge from Optical Emission-line IFU Spectroscopy
- 2019
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Ingår i: Astrophysical Journal. - : American Astronomical Society. - 0004-637X .- 1538-4357. ; 878:2
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Tidskriftsartikel (refereegranskat)abstract
- We present optical integral field unit observations of the Taffy system (UGC 12914/15), named for the radio emission that stretches between the two galaxies. Given that these gas-rich galaxies are believed to have recently collided head-on, the pair exhibits a surprisingly normal total (sub-LJRG) IR luminosity (L-FIR similar to 4.5 x 10(10) L-circle dot). Previous observations have demonstrated that a large quantity of molecular and neutral gas has been drawn out of the galaxies into a massive multiphase bridge. We present, for the first time, spatially resolved spectroscopy of the ionized gas in the system. The results show that the ionized gas is highly disturbed kinematically, with gas spread in two main filaments between the two galaxies. The line profiles exhibit widespread double components in both the bridge and parts of the disks of the galaxies. We investigate the spatial distribution of the excitation properties of the ionized gas using emission-line diagnostic diagrams and conclude that a large quantity (up to 40%) of the emission from the entire system is consistent with gas heated in similar to 200 km s(-1) shocks. While the shocked gas is mainly associated with the bridge, there is a significant amount of shocked gas associated with both galaxies. Confirming other multiwavelength indicators, the results suggest that the effects of shocks and turbulence can continue to be felt in a high-speed galaxy collision long after the collision has occurred. The persistence of shocks in the Taffy system may explain the relatively low current star formation rates in the system as a whole.
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| 5. |
- Regnéll, Carl, et al.
(författare)
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Ice-dammed lakes and deglaciation history of the Scandinavian Ice Sheet in central Jämtland, Sweden
- 2023
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Ingår i: Quaternary Science Reviews. - : PERGAMON-ELSEVIER SCIENCE LTD. - 0277-3791 .- 1873-457X. ; 314
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Tidskriftsartikel (refereegranskat)abstract
- Extensive glacial lakes dammed in the Scandinavian Mountains during the retreat of the last Scandinavian Ice Sheet were first hypothesised over a century ago. Here, using high-resolution LiDAR, we report >4500 relict shorelines, deltas and palaeo-channels related to ice-dammed lakes over a -30 000 km2 area of central Jämtland, west-central Sweden. Shorelines occur as flights on the valley sides, a consequence of sequential lowering of palaeo-lake levels during ice margin retreat and lower threshold outlets becoming ice-free. Based on the extent and elevation of shorelines, we identify requisite lake-damming ice-margin positions and lake drainage outlets, and we reconstruct the coupled evolution of ice-dammed lakes and the retreating ice margin. Beginning as a series of smaller ice-dammed lakes along the Swedish-Norwegian border, draining westward across the present-day water divide and into the Atlantic Ocean, the lakes successively coalesced during eastward ice margin retreat to form water bodies covering 1000s of km2 with 10s of km-long calving margins. Ultimately, the lake system coalesced into a single lake: the Central Jämtland Ice Lake, which exceeded 3500 km2 in area and 360 km3 in volume. Eventually, the damming ice-margin split in two, resulting in a large (-200 km2) catastrophic glacial lake outburst flood (GLOF) that reversed the drainage of the entire lake system from the west to an eastern outlet draining to the Baltic basin. We present new radiocarbon ages for one lake drainage event prior to the eastward outburst flood and, together with previously published deglacial ages and local varve records, we suggest that the region was possibly deglaciated within just 350 years, sometime between 10.5 and 9.2 cal ka BP. We tentatively correlate the penultimate drainage of the Central Jämtland Ice Lake to the zero-varve of the Swedish Time Scale, a drainage varve at Döviken, eastern Jämtland, raising the tantalising prospect of using the evolution of the ice-dammed lake system to tie the varve-based Swedish Time Scale to the radiocarbon timescale with a new programme of radiocarbon dating in central Jämtland.
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| 6. |
- Regnéll, Joachim, 1956-, et al.
(författare)
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Ice-dammed lakes of Scandinavia : A key to the pattern and chronology of the final decay of the Scandinavian ice-sheet
- 2021
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Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Here we present the use of ice-dammed lake-related landforms and sediments for reconstructing the final phases of decay of the Scandinavian Ice Sheet.In the late stages of the deglaciation, extensive glacial lakes were dammed between the easterly retreating Scandinavian Ice Sheet and the water divide within the mountains to the west. Using high-resolution airborne LiDAR-data, shorelines and other landforms relating to these ice-dammed lakes have now been discovered over larger areas and in greater numbers than previously known, opening a treasure trove of palaeoglaciological information of vast potential for reconstructing the final decay phase of the Scandinavian Ice Sheet.The geomorphological imprint of the ice-dammed lakes is of particular importance in northern Scandinavia, as geological evidence pertaining unequivocally to the final ice sheet decay is sparse. Its interpretation is complicated since the ice sheet is thought to have mainly been cold-based during final decay, inhibiting sliding at the ice-bed interface and limiting the construction (or destruction) of landforms indicative of the changing shape and flow of the ice sheet. Furthermore, dated sediment sequences marking the onset of ice-free conditions are woefully few in northern Scandinavia. Likewise, available cosmogenic nuclide exposure dates provide high age uncertainty and inadequate geographical cover, leaving the timing and location of final ice sheet decay still elusive.Using examples from northern and central Scandinavia, we show that ice-dammed lakes are an intricate part of the deglacial dynamics and show how mapping and dating them offer a solution to these problems. Even with a frozen ice-bed interface, surface melting and meltwater drainage creates landforms unequivocally associated with ice sheet decay: drainage channels, dammed lake shorelines, and deltas. Meltwater drainage routes and ice-dammed lakes are therefore powerful tools for reconstructing a disintegrating ice sheet; a ponded lake reveals the location of its requisite ice-dam, and drainage pathways reveal ice-free conditions. A dated sequence of ice-dammed lake sediments can therefore constrain both ice and lake coverage at that time for a much larger area than the dated site itself. Furthermore, the extent of different ice-dammed lake stages and their requisite ice-damming positions enables the pattern of ice margin change to be traced, and the relative age of ice-marginal positions determined using cross-cutting relations. The shorelines’ present-day tilts are also used to inform patterns and magnitudes of postglacial isostatic uplift, information otherwise lacking from the continental interior but of particular importance for modelling former ice sheet volumes and understanding the crustal response to ice sheet loading. Reconstructing the extents and timing of ice-dammed lakes and the study of related landforms and deposits can therefore greatly improve our understanding of the final decay of the Scandinavian Ice Sheet and provide potential analogues for the predicted future behaviours of modern ice sheets.
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| 7. |
- Regnéll, Joachim, et al.
(författare)
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Ice-dammed lakes of Scandinavia : A key to the pattern and chronology of the final decay of the Scandinavian ice-sheet
- 2021
-
Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
- Here we present the use of ice-dammed lake-related landforms and sediments for reconstructing the final phases of decay of the Scandinavian Ice Sheet. In the late stages of the deglaciation, extensive glacial lakes were dammed between the easterly retreating Scandinavian Ice Sheet and the water divide within the mountains to the west. Using high-resolution airborne LiDAR-data, shorelines and other landforms relating to these ice-dammed lakes have now been discovered over larger areas and in greater numbers than previously known, opening a treasure trove of palaeoglaciological information of vast potential for reconstructing the final decay phase of the Scandinavian Ice Sheet. The geomorphological imprint of the ice-dammed lakes is of particular importance in northern Scandinavia, as geological evidence pertaining unequivocally to the final ice sheet decay is sparse. Its interpretation is complicated since the ice sheet is thought to have mainly been cold-based during final decay, inhibiting sliding at the ice-bed interface and limiting the construction (or destruction) of landforms indicative of the changing shape and flow of the ice sheet. Furthermore, dated sediment sequences marking the onset of ice-free conditions are woefully few in northern Scandinavia. Likewise, available cosmogenic nuclide exposure dates provide high age uncertainty and inadequate geographical cover, leaving the timing and location of final ice sheet decay still elusive. Using examples from northern and central Scandinavia, we show that ice-dammed lakes are an intricate part of the deglacial dynamics and show how mapping and dating them offer a solution to these problems. Even with a frozen ice-bed interface, surface melting and meltwater drainage creates landforms unequivocally associated with ice sheet decay: drainage channels, dammed lake shorelines, and deltas. Meltwater drainage routes and ice-dammed lakes are therefore powerful tools for reconstructing a disintegrating ice sheet; a ponded lake reveals the location of its requisite ice-dam, and drainage pathways reveal ice-free conditions. A dated sequence of ice-dammed lake sediments can therefore constrain both ice and lake coverage at that time for a much larger area than the dated site itself. Furthermore, the extent of different ice-dammed lake stages and their requisite ice-damming positions enables the pattern of ice margin change to be traced, and the relative age of ice-marginal positions determined using cross-cutting relations. The shorelines’ present-day tilts are also used to inform patterns and magnitudes of postglacial isostatic uplift, information otherwise lacking from the continental interior but of particular importance for modelling former ice sheet volumes and understanding the crustal response to ice sheet loading. Reconstructing the extents and timing of ice-dammed lakes and the study of related landforms and deposits can therefore greatly improve our understanding of the final decay of the Scandinavian Ice Sheet and provide potential analogues for the predictedfuture behaviours of modern ice sheets.
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| 8. |
- Röhr, Maria Emilia, et al.
(författare)
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Blue Carbon Storage Capacity of Temperate Eelgrass (Zostera marina) Meadows
- 2018
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Ingår i: Global Biogeochemical Cycles. - 0886-6236 .- 1944-9224. ; 32:10, s. 1457-1475
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Tidskriftsartikel (refereegranskat)abstract
- Despite the importance of coastal ecosystems for the global carbon budgets, knowledge of their carbon storage capacity and the factors driving variability in storage capacity is still limited. Here we provide an estimate on the magnitude and variability of carbon stocks within a widely distributed marine foundation species throughout its distribution area in temperate Northern Hemisphere. We sampled 54 eelgrass (Zostera marina) meadows, spread across eight ocean margins and 36° of latitude, to determine abiotic and biotic factors influencing organic carbon (Corg) stocks in Zostera marina sediments. The Corg stocks (integrated over 25-cm depth) showed a large variability and ranged from 318 to 26,523gC/m2 with an average of 2,721gC/m2. The projected Corg stocks obtained by extrapolating over the top 1m of sediment ranged between 23.1 and 351.7MgC/ha, which is in line with estimates for other seagrasses and other blue carbon ecosystems. Most of the variation in Corg stocks was explained by five environmental variables (sediment mud content, dry density and degree of sorting, and salinity and water depth), while plant attributes such as biomass and shoot density were less important to Corg stocks. Carbon isotopic signatures indicated that at most sites <50% of the sediment carbon is derived from seagrass, which is lower than reported previously for seagrass meadows. The high spatial carbon storage variability urges caution in extrapolating carbon storage capacity between geographical areas as well as within and between seagrass species.
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| 9. |
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- 2019
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Tidskriftsartikel (refereegranskat)
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